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Monte Carlo-based optimization of glioma capsule design for enhanced brachytherapy
Appl Radiat Isot. 2023 Sep 5;201:111014. doi: 10.1016/j.apradiso.2023.111014. Online ahead of print.ABSTRACTThe use of radiotherapy in tumor treatment has become increasingly prominent and has emerged as one of the main tools for treating malignant tumors. Current radiation therapy for glioma employs 125I seeds for brachytherapy, which cannot be combined with radiotherapy and chemotherapy. To address this limitation, this paper proposes a dual-microcavity capsule structure that integrates radiotherapy and chemotherapy. The Monte Carlo simulation method is used to simulate the structure of the dual-microcavity capsule with ...
Source: Applied Radiation and Isotopes - September 9, 2023 Category: Radiology Authors: Dongjie Li Yu Liang Gang Yao Zhongbao Guan Hongtao Zhao Nan Zhang Jicheng Jiang Weida Gao Source Type: research

Actinium-225 Targeted Agents: Where Are We Now?
α-particle targeted radionuclide therapy has shown promise for optimal cancer management, an exciting new era for brachytherapy. Alpha-emitting nuclides can have significant advantages over gamma- and beta-emitters due to their high linear energy transfer (LET). While their limited path length resu lts in more specific tumor 0kill with less damage to surrounding normal tissues, their high LET can produce substantially more lethal double strand DNA breaks per radiation track than beta particles. Over the last decade, the physical and chemical attributes of Actinium-225 (225Ac) including its hal f-life, decay schemes, path ...
Source: Brachytherapy - September 8, 2023 Category: Cancer & Oncology Authors: Firas Mourtada, Katsumi Tomiyoshi, Jennifer Sims-Mourtada, Yuki Mukai-Sasaki, Takayuki Yagihashi, Yuta Namiki, Taro Murai, David J. Yang, Tomio Inoue Tags: Invited Perspectives and Reviews Source Type: research

Effects of iodine-125 seed brachytherapy on patients with heterochronous pulmonary metastasis from hepatocellular carcinoma: A propensity score matching study
CONCLUSION: ISB improves local control and OS rates of HPM secondary to HCC; thus, it is an effective and feasible option for patients with HPM secondary to HCC.PMID:37675723 | DOI:10.4103/jcrt.jcrt_519_22
Source: Cancer Control - September 7, 2023 Category: Cancer & Oncology Authors: Chongshuang Yang Chuang He Songtao Yu Jing Yuan Yunhua Xiao Xuequan Huang Source Type: research

Reirradiation salvage radiotherapy for recurrent prostate cancer after primary low-dose brachytherapy
CONCLUSIONS: Our data suggest that the treatment of locally recurrent prostate cancer with S-EBRT could provide adequate disease control safely and be used as an additional treatment in the natural history of prostate cancer patients. However, the results are still early and the sample is small; larger studies with longer follow-up would be mandatory.PMID:37672205 | DOI:10.1007/s12094-023-03315-1
Source: Clinical Prostate Cancer - September 6, 2023 Category: Cancer & Oncology Authors: Óscar Muñoz Muñoz El ías Gomis Sellés Blas David Delgado Le ón Juan Carlos Mateos Perez Montserrat Baeza Trujillo Maria Perucha Ortega Jos é Luis López Guerra Patricia Cabrera Rold án Source Type: research

Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
Condition:   Rhabdomyosarcoma Interventions:   Drug: Vincristine;   Drug: Dactinomycin;   Drug: Cyclophosphamide;   Procedure: Surgical Resection;   Procedure: Proton beam radiation or external beam radiation or brachytherapy;   Drug: Liposomal irinotecan;   Drug: Vinorelbine;   Drug: Temozolomide;   Drug: Filgrastim, peg- filgrastim Sponsor:   St. Jude Children's Research Hospital Not yet recruiting
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials

Virtual reality technology: A potential tool to enhance brachytherapy training and delivery
Virtual reality (VR), a virtual environment that is designed to be perceived as reality, has been around for many decades but recent improvements in computer processing power, battery capacity, and cost have made it more accessible and available. Current systems allow for a user to wear a headset that replaces the field of vision in both eyes with stereoscopic screens, generating imagery that the brain interprets in three dimensions and allowing the user to be immersed in an entirely virtual environment.
Source: Brachytherapy - September 5, 2023 Category: Cancer & Oncology Authors: Arpan V. Prabhu, Melissa Peterman, Anam Kesaria, Santanu Samanta, Richard Crownover, Gary D. Lewis Source Type: research