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Total 4460783 results found since Jan 2013.

Evaluation of the dosimetric impact of loss and displacement of seeds in prostate low-dose-rate brachytherapy.
CONCLUSIONS: Seed loss and displacement have been observed to be frequent. No correlation between seed loss and displacement and post-plan dosimetry has been reported. PMID: 26207108 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A novel perineal shield for low-dose-rate prostate brachytherapy.
CONCLUSIONS: Our novel shield took seconds to install and was non-restrictive during the procedure, and provided at least a four-fold reduction in radiation exposure to the brachytherapist. PMID: 26207107 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Commissioning and periodic tests of the Esteya(®) electronic brachytherapy system.
Authors: Candela-Juan C, Niatsetski Y, Ouhib Z, Ballester F, Vijande J, Perez-Calatayud J Abstract A new electronic brachytherapy unit from Elekta, called Esteya(®), has recently been introduced to the market. As a part of the standards in radiation oncology, an acceptance testing and commissioning must be performed prior to treatment of the first patient. In addition, a quality assurance program should be implemented. A complete commissioning and periodic testing of the Esteya(®) device using the American Association of Physicists in Medicine (AAPM), Groupe Européen de Curiethérapie and the European Society fo...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate pre-operative endorectal brachytherapy for patients with rectal cancer.
We describe technical aspects of the HDREBT and we discuss the ongoing institutional review board approved studies exploring the clinical applications of this treatment modality for patients with rectal cancer: 1) as a neoadjuvant treatment for patients with operable rectal tumor; 2) as a option to improve local control in patients with newly diagnosed rectal cancer but with previous pelvic radiation. PMID: 26034500 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evaluation of (101)Rh as a brachytherapy source.
CONCLUSIONS: (101)Rh is proposed as an alternative to the existing HDR sources for use in brachytherapy. This source provides medium energy photons, relatively long half-life, higher dose rate constant and radial dose function, and similar 2D anisotropy function to the Flexisource (192)Ir HDR source design. The longer half-life of the source reduces the frequency of the source exchange for the clinical environment. PMID: 26034499 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Tandem-ring dwell time ratio in Nigeria: dose comparisons of two loading patterns in standard high-dose-rate brachytherapy planning for cervical cancer.
CONCLUSION: Tandem-ring dwell time ratio has significant influence on dosimetric parameters. This study has indicated the need to modify the existing planning approach at UCH. PMID: 26034498 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dosimetric analysis and clinical outcomes in CT-based mould brachytherapy in early oral cancers in patients unfit for surgery.
CONCLUSIONS: Mould therapy is an effective treatment method for selected early and superficial squamous cell carcinomas of the oral cavity, although indications are limited. PMID: 26034496 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A study of high-dose-rate intracavitary brachytherapy boost for curative treatment of uterine cervical cancer.
CONCLUSIONS: The method to perform dose escalation should be examined depending on the treatment response. PMID: 26034493 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Recurrent Bowen's disease of scalp treated with high dose rate surface mold brachytherapy: a case report and review of the literature.
Authors: Gandhi AK, Laviraj MA, Kashyap L, Purkait S, Sharma DN, Julka PK, Rath GK Abstract Our case is a 46-year-old female presenting to us with Bowen's disease of scalp since 5 years. Patient had failed topical therapy with 5% 5-florouracil, 0.1% tacrolimus and was intolerant to topical imiquimod. At presentation, she had 15 cm × 10 cm erythematous, hyperpigmented, crusted plaque with irregular border in the superior and lateral aspect of left side of scalp with extension in to forehead. Patient was treated with computed tomography based customized surface mold high dose rate brachytherapy with Iridium-192 to a...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Multi-axis dose accumulation of noninvasive image-guided breast brachytherapy through biomechanical modeling of tissue deformation using the finite element method.
CONCLUSIONS: The model exhibited skin dose trends that matched MC-generated benchmarking results within 2% and clinical observations over a similar range of breast thicknesses and target sizes. The model provided quantitative insight on dosimetric treatment variables over a range of clinical circumstances. These findings highlight the need for careful target localization and accurate identification of compression thickness and target offset. PMID: 25829938 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate vaginal brachytherapy with chemotherapy for surgically staged localized uterine serous carcinoma.
CONCLUSIONS: Excellent vaginal/pelvic control rates were observed. Further study of HDR brachytherapy dose and fractionation in combination with chemotherapy is worthwhile. PMID: 25829935 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy - a literature review.
Authors: Pellizzon AC Abstract The treatment strategies for adult soft tissue sarcomas of the extremities place an emphasis on local control, maintenance of limb function, and quality of life. Surgery is the mainstay of treatment for soft tissue sarcomas. Radiotherapy and chemotherapy are also both important treatments used in these patients to optimize the outcomes of limb sparing surgery. Compared to external beam radiation therapy, brachytherapy has the advantage of delivering a concentrated dose to the tumor, whilst sparing the normal tissues. Consequently, early and late complications such as bone fractures an...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

A simple technique for the generation of institution-specific nomograms for permanent prostate cancer brachytherapy.
CONCLUSIONS: It is appropriate for each institution to develop nomograms specific to their prostate brachytherapy technique and constraints. Nomograms can estimate the number and strength of seeds to be ordered, and may partially compensate for the effects of implant-induced swelling. PMID: 25337132 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The impact of activating source dwell positions outside the CTV on the dose to treated normal tissue volumes in TRUS guided 3D conformal interstitial HDR brachytherapy of prostate cancer.
CONCLUSIONS: It is possible to reduce the V100, normal tissue by decreasing the source dwell positions outside the CTV from 5 to 3 mm, while maintaining dose constraints. In combination with the estimated geometrical uncertainties, however, the source dwell positions need to be 5 mm from the surface in order to maintain a robust implant. PMID: 25337130 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Metformin is not associated with improved biochemical free survival or cause-specific survival in men with prostate cancer treated with permanent interstitial brachytherapy.
CONCLUSIONS: Metformin use was not associated with improved biochemical survival or cancer specific survival in this cohort of men treated with prostate brachytherapy. PMID: 25337126 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research