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Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA.
CONCLUSIONS: Gamma analysis showed good agreement between dose distributions calculated using TPS and measured by Gafchromic films, thus showing the viability of using film dosimetry in brachytherapy. PMID: 27648087 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Modelling the radiobiological effect of intraoperative X-ray brachytherapy for breast cancer using an air-filled spherical applicator.
CONCLUSIONS: The 'shell of isoeffect' can serve as a useful metric with which to compare the radiobiological effectiveness of low kV eBT with various regimes of conventional EBRT. PMID: 27648085 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Neither high-dose nor low-dose brachytherapy increases flap morbidity in salvage treatment of recurrent head and neck cancer.
CONCLUSIONS: In patients who undergo flap reconstruction and immediate postoperative radiotherapy following salvage procedures for RH&NC, flap coverage of defects in combination with brachytherapy remains a safe and effective means of providing stable soft tissue coverage. PMID: 27648084 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Trans-hepatic technique and intraluminal Pulsed Dose Rate (PDR-BT) brachytherapy in treatment of locally advanced bile duct and pancreas cancer.
CONCLUSIONS: 1. It has been established, that the use of PDR-BT was feasible and had a low early complication rate. A new percutaneous trans-hepatic technique allowed the treatment (insertion of catheter, PDR brachytherapy) to be performed in one day. 2. In most cases a satisfied palliative effect was achieved, however it was more apparent in bile duct cancer patients then in pancreas cancer patients. PMID: 27795719 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 2, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

PSA bouncing after brachytherapy HDR and external beam radiation therapy: a study of 121 patients with minimum 5-years follow-up.
CONCLUSIONS: PSA bouncing occurs in approximately a one third (1/3) of patients treated with 3D-CRT and brachytherapy HDR. Bouncing is associated with age, higher pretreatment PSA level and increased V200 factor. PMID: 27795718 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 2, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Interstitial brachytherapy guided intensity modulated radiation therapy (IBGIMRT) in cervical cancer: a dosimetric study.
CONCLUSIONS: Our novel technique, IBGIMRT, has shown its dosimetric superiority and therefore needs to be studied in clinical set up. PMID: 27795717 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 2, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Cosmetic effect in patients with early breast cancer treated with breast conserving therapy (BCT) and with HDR brachytherapy (HDR-BT) "boost".
CONCLUSIONS: HDR-BT tolerance was good in most of the cases. Excellent and very good cosmetic effect was observed in 79 patients (85%). Statistically important correlations between following examined prognostic factors and cosmetics outcome were observed: clinical and mammographic tumor estimation, method of breast conserving surgery, type of skin incision, number of interstitial applicators, irradiated reference volume (PTV) and type of optimization method. No correlations with cosmetics effect were found in factors such as: age of patients, location of tumor or additional therapy. PMID: 27795716 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 2, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Feasibility of functional imaging for brachytherapy.
Authors: Polo A Abstract This review summarizes the current understanding of the feasibility of functional imaging for brachytherapy. In following subsections the role of ultrasound, power doppler imaging, positron emission tomography, magnetic resonance imaging, dynamic dose calculation and targeted brachytherapy is analyzed. The combination of functional imaging with the new tools for intraoperative dose calculation and optimization opens new and exciting times in brachytherapy. New optimized protocols are needed and should be tested in controlled trials, to demonstrate an advantage of such a new paradigm. PM...
Source: Journal of Contemporary Brachytherapy - November 4, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Tolerance and efficacy of preoperative intracavitary HDR brachytherapy in IB and IIA cervical cancer.
CONCLUSIONS: 1. Preoperative HDR-BT in patients with IB and IIA cervical cancer is an effective and well tolerated therapy with acceptable rate of side effects. 2. Preoperative HDR-BT followed by surgery in a group without risk factors is a sufficient treatment option with no additional adjuvant therapy requirement. PMID: 27799952 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 4, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

HDR brachytherapy (HDR-BT) combined with stent placement in palliative treatment of esophageal cancer.
CONCLUSIONS: 1. Endoscopic implantation of stents to the lumen of the esophagus provides access to esophagus and, in many cases, allows application of HDR-BT. 2. HDR-BT for advanced esophageal cancer brought relief from dysphagia in most of patients. 3. The combination of the two methods of treatment represents an effective choice for palliative care of this group of patients, with a complication rate similar to observed one in the instance of brachytherapy alone. PMID: 27799950 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 4, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Boost in radiotherapy: external beam sunset, brachytherapy sunrise.
Authors: Maciejewski B Abstract Radiobiological limitations for dose escalation in external radiotherapy are presented. Biological and clinical concept of brachytherapy boost to increase treatment efficacy is discussed, and different methods are compared. Oncentra Prostate 3D conformal real-time ultrasound-guided brachytherapy is presented as a solution for boost or sole therapy. PMID: 27799947 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 4, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

HDR and PDR (192)Ir source activity control procedures, as the part of the quality assurance system at Brachytherapy Department of Greater Poland Cancer Centre.
CONCLUSIONS: Checking of source parameters is one of the most important parts of quality control system in brachytherapy facilities. Well chamber and thimble chamber based dosimetry systems are fast and reliable tools for (192)Ir source parameters checking in working brachytherapy department conditions. PMID: 27807459 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

The consistency of Fletcher-Suit applicator geometry and of the rectal probe's position in high dose rate brachytherapy treatment fraction of cervix carcinoma.
Authors: Pálvölgyi J Abstract PURPOSE: The dose values computed with the treatment planning system and the in vivo dose measurements with semiconductor detectors in rectum during the high dose rate brachytherapy treatment fraction of the cervix carcinoma are occasionally significantly different. We've investigated the consistency of the Fletcher-Suit applicator geometry and the in vivo rectal probe's position stability during the high dose rate brachytherapy treatment fraction. MATERIAL AND METHODS: The patient lied in a lithotomic position during a biplane reconstruction images, throughout the treatment plan...
Source: Journal of Contemporary Brachytherapy - November 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Reexcision and perioperative high-dose-rate brachytherapy in the treatment of local relapse after breast conservation: an alternative to salvage mastectomy.
CONCLUSIONS: Second breast-conserving surgery followed by partial breast reirradiation is a safe and effective option for the management of selected patients developing local recurrence after previous breast-conserving therapy. Perioperative high-dose-rate brachytherapy with adequate fractionation may decrease the risk of second local relapse with acceptable cosmetic results and low rate of late side effects. PMID: 27807454 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - November 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy in paediatric malignancies - review of indications.
Authors: Fijuth J Abstract Paediatric malignancies are relatively rare, with an annual frequency of 13-14 in 100 000 children up to 15 years, and account for less than 1% of all cancer in developed countries. Paediatric tumours are generally managed with a multi-modality treatment programme that includes surgery, chemotherapy, and external beam radiation therapy (EBRT). Treatment strategies directed towards the reduction of late side effects have significantly increased interest in brachytherapy, in particular of soft tissue sarcoma and clear cell adenocarcinoma, as in these malignancies often only a limited target...
Source: Journal of Contemporary Brachytherapy - November 14, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research