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Brachytherapy in the treatment of bile duct cancer - a tough challenge.
The objective of this treatment is to deliver a high local dose of radiation to the tumor while sparing surrounding healthy tissues. The treatment can be safely adapted for right and left hepatic duct, and for common bile duct lesions. Brachytherapy plays a limited but specific role in definitive treatment with curative intent in selected cases of early disease, as well as in the postoperative treatment of small residual disease. Depending on the location of the lesion, in some cases, brachytherapy is a treatment of choice. Clinical indications, different techniques, results, and complications are discussed in this work.
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Source: Journal of Contemporary Brachytherapy - May 25, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Computed tomography-guided implantation of (125)I seeds brachytherapy for recurrent multiple pulmonary oligometastases: initial experience and results.
CONCLUSIONS: CT-guided (125)I brachytherapy is a safe and effective treatment for multiple pulmonary metastatic tumors, and can achieve good short-term local control, so long as the radiation dose is sufficient.
PMID: 28533801 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - May 25, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
High-dose-rate interstitial brachytherapy in head and neck cancer: do we need a look back into a forgotten art - a single institute experience.
CONCLUSIONS: The overall outcome was good with implementation of HDR-BRT used alone or as boost, and shows DFS as better when the dose received is more than the median BED and median EQD2. The role of HDR-BRT in HNC is a proven, effective, and safe treatment method with excellent long term outcome as seen in this study, which reflects the need for reviving the forgotten art and science of interstitial brachytherapy in HNC.
PMID: 28533800 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - May 25, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Optimal bladder filling during high-dose-rate intracavitary brachytherapy for cervical cancer: a dosimetric study.
CONCLUSIONS: Bladder filling protocol with 50 ml and 100 ml was well tolerated and achieved a reasonably reproducible bladder volume during cervical brachytherapy. In our analysis so far, there is no significant impact of bladder filling on DVH parameters, although larger bladders tend to have higher doses. Small bowel doses are lesser with higher bladder volumes. Further evaluation and validation are necessary.
PMID: 28533798 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - May 25, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
High-dose-rate interstitial brachytherapy for accelerated partial breast irradiation - trial results of Azerbaijan National Center of Oncology.
CONCLUSIONS: Accelerated partial breast irradiation using multicatheter brachytherapy with 32 Gy/8 fractions and 35 Gy/7 fractions for early breast cancer seems to be similar in terms of late side effects. According to our findings, APBI was also feasible for intermediate-risk of early breast cancer patients.
PMID: 28533797 [PubMed - in process]
Source: Journal of Contemporary Brachytherapy - May 25, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
INTERACTS (INTErventional Radiotherapy ACtive Teaching School) guidelines for quality assurance in choroidal melanoma interventional radiotherapy (brachytherapy) procedures.
Authors: Tagliaferri L, Pagliara MM, Boldrini L, Caputo CG, Azario L, Campitelli M, Gambacorta MA, Smaniotto D, Frascino V, Deodato F, Morganti AG, Kovács G, Valentini V, Blasi MA
Abstract
Eye plaque brachytherapy represents a safe and effective therapeutic approach for choroidal melanoma, combining clinical outcomes with an eye and visual preservation. As it represents a complex procedure, a specific quality assurance program is strongly suggested to improve patients and operators safety, and to reduce possible complications linked to surgical procedure and radiation exposure. The aim of this paper is to describe...
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Computed tomography-based treatment planning for high-dose-rate brachytherapy using the tandem and ring applicator: influence of applicator choice on organ dose and inter-fraction adaptive planning.
Authors: Dumane VA, Yuan Y, Sheu RD, Gupta V
Abstract
Three dimensional planning for high-dose-rate (HDR) brachytherapy in cervical cancer has been highly recommended by consensus guidelines such as the American Brachytherapy Society (ABS) and the Groupe Européen de Curiethérapie - European Society for Radiotherapy and Oncology (GEC-ESTRO). In this document, we describe our experience with computed tomography (CT)-based planning using the tandem/ring applicator. We discuss the influence of applicator geometry on doses to organs at risk (OARs), namely the bladder, rectum, and sigmoid. Through example cases with do...
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Two years results of electronic brachytherapy for basal cell carcinoma.
CONCLUSIONS: This work is special, since the equipment's treatment voltage was 69.5 kV, and this is the first prospective study with long term follow-up with Esteya(®). These preliminary report show excellent results with less toxicity and excellent cosmesis. While surgery has been the treatment of choice, certain patients might benefit from eBT treatment. These are elderly patients with comorbidities or undergoing anticoagulant treatment as well as those who simply refuse surgery or might have other contraindications.
PMID: 28725249 [PubMed]
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Effects of vaginal cylinder position on dose distribution in patients with endometrial carcinoma in treatment of vaginal cuff brachytherapy.
CONCLUSIONS: Vaginal cuff brachytherapy in the P and A positions is significantly superior to that in the N position in terms of rectum dosimetry. The bladder dose in the N position is considerably lower than that in the other positions.
PMID: 28725246 [PubMed]
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
The usefulness of fleet rectal enemas on high-dose-rate intracavitary cervical cancer brachytherapy. A prospective trial.
CONCLUSIONS: Our rectal enemas protocol prior to HDR-BT was ineffective in significantly modifying rectal DVH parameters. No differences were observed according to the type of applicator used.
PMID: 28725245 [PubMed]
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Optimal perioperative anesthesia management for gynecologic interstitial brachytherapy.
CONCLUSIONS: Interstitial gynecologic brachytherapy requires a multidisciplinary effort for optimal perioperative management. Our study outlines the appropriate preoperative, intraoperative, and postoperative anesthesia clinical care pathway. Decreased narcotic use during hospitalization and utilization of a patient-directed infusion may decrease side effects and allow for a more efficient hospital discharge.
PMID: 28725244 [PubMed]
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Focal application of low-dose-rate brachytherapy for prostate cancer: a pilot study.
CONCLUSIONS: Low-dose-rate brachytherapy is a favorable ablation option for focal treatment of prostate cancer, requiring minimal modification to the standard (whole gland) LDR-PB treatment, and appears to have a more favorable side effect profile. Further investigation, in the form of a larger study, is needed to assess the methods used and the long-term outcomes of focal LDR-PB.
PMID: 28725242 [PubMed]
Source: Journal of Contemporary Brachytherapy - July 21, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Magnetic resonance imaging-based salvage brachytherapy: Moving toward a focal paradigm
This article aims to review the current literature on whole gland salvage brachytherapy for radiorecurrent prostate cancer as well as the methodology and progress towards a focal approach to salvage brachytherapy. Particular emphasis is placed on the potential role of multiparametric MRI in achieving optimal outcomes with focal salvage brachytherapy.
Source: Brachytherapy - May 4, 2017 Category: Cancer & Oncology Authors: Marisa A. Kollmeier, Michael Zelefsky, Sean McBride Tags: Magnetic Resonance Imaging-Based Brachytherapy Source Type: research
Robot-assisted brachytherapy of the bladder with long distance support using video conferencing.
CONCLUSIONS: The previously reported good rates of tumor control and survival, and the excellent tolerance and low morbidity support RALB as a promising approach for selected groups of patients with localized MIBC. This case illustrates the ability to expand efficiently this technique, particularly among inexperienced medical teams.
PMID: 28951758 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 29, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Inflatable multichannel rectal applicator for adaptive image-guided endoluminal high-dose-rate rectal brachytherapy: design, dosimetric characteristics, and first clinical experiences.
CONCLUSION: The use of the applicator was clinically feasible, and resulted in a stable and reproducible dose distribution. First clinical results are promising.
PMID: 28951756 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 29, 2017 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
