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Total 4460783 results found since Jan 2013.
Risk factors for fistula formation after interstitial brachytherapy for locally advanced gynecological cancers involving vagina.
Conclusions: We identified factors that predict fistula formation in patients with advanced gynecologic tumors treated with ISBT. These factors can be used to stratify patients into a high-risk group, with potential for modification of brachytherapy planning to reduce their risk of fistula formation.
PMID: 30662473 [PubMed]
Source: Journal of Contemporary Brachytherapy - January 23, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Cost in perspective: direct assessment of American market acceptability of Co-60 in gynecologic high-dose-rate brachytherapy and contrast with experience abroad.
Conclusions: By comparing the cost of additional shielding for a sample institution's HDR suite with radiation oncologists' WTP, this multi-institutional collaboration noted < 20% of clinicians would accept additional shielding. Despite low acceptability in the US, Co-60 demonstrates cost-favorability in Peru and may similarly in other locations.
PMID: 30662472 [PubMed]
Source: Journal of Contemporary Brachytherapy - January 23, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Monte Carlo dosimetry for a new 32P brachytherapy source using FLUKA code.
Conclusions: This work fully characterizes dosimetric parameters of the sheathed and unsheathed new 32P brachytherapy sources in water and different tissue phantoms by using FLUKA code. The results demonstrate that the dose distribution in water differed from the calculated ones in tissue phantoms due to the densities and atomic composition for tissues that are not taken account by the TG-60 formalism.
PMID: 30911314 [PubMed]
Source: Journal of Contemporary Brachytherapy - March 27, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Subdermal injection of hyaluronic acid to decrease skin toxicity from radiation delivered with low-dose-rate brachytherapy for cancer patients.
Conclusions: Our study results showed that an additional 1.0 cm distance between the radioactive source and skin could be induced by HA injection in patients with subdermal tumor, and this distance could significantly decrease the skin dose in LDR brachytherapy. In addition, no obvious toxicity and side effects were produced by HA injection. Therefore, hyaluronic acid injection is a safe and effective technique.
PMID: 30911305 [PubMed]
Source: Journal of Contemporary Brachytherapy - March 27, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Impact of different dose prescription schedules on EQD2 in high-dose-rate intracavitary brachytherapy of carcinoma cervix.
Conclusions: EQD2 of bladder, rectum, sigmoid, D90 CTVHR, and point A were similar with 5.5 Gy × 5 fractions, 6.5 Gy × 4 fractions, and 7 Gy × 4 fractions, whereas EQD2 of 9 Gy × 2 fractions was significantly unfavorable compared to other schedules. Further clinical studies are recommended to observe clinical outcomes.
PMID: 31139229 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
First report on extended distance between tumor lesion and adjacent organs at risk using interventionally applied balloon catheters: a simple procedure to optimize clinical target volume covering effective isodose in interstitial high-dose-rate brachytherapy of liver malignomas.
Conclusions: The distancing of the adjacent OARs allows a higher D100 value of CTV, therefore allowing for more efficient local control.
PMID: 31139224 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Assessment of the anatomical position of point B and the relationship between point B dose and the dose delivered to pelvic lymph nodes in CT-based high-dose-rate brachytherapy for uterine cervical cancer.
Conclusions: We investigated the anatomical location of point B in patients with cervical cancer who underwent brachytherapy, and the DVH analysis revealed that the point B dose was a poor surrogate for the dose delivered to the pelvic lymph nodes.
PMID: 31139222 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
The impact of inter-fraction changes for perineal template-based interstitial gynecologic brachytherapy implants.
Conclusions: The implementation of perineal template-based ISBT treatment without inter-fraction adaptive planning can be delivered to comply with the ABS normal tissue dose guidelines and EMBRACE II limits for prescribed dose.
PMID: 31139220 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Adjuvant interstitial three-dimensional pulse-dose-rate-brachytherapy for lip squamous cell carcinoma after surgical resection.
Conclusions: PDR-BT in the adjuvant treatment of the lip cancer yields high local control with low toxicity. Even patients with close margins after surgery (< 5 mm) should be considered as candidates for PDR-BT.
PMID: 31139219 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Second breast-conserving therapy with interstitial brachytherapy (APBI) as a salvage treatment in ipsilateral breast tumor recurrence: a retrospective study of 40 patients.
Conclusions: Second BCT with APBI as a salvage treatment in ipsilateral breast recurrence achieves good local disease control, with a satisfactory toxicity profile compared to mastectomy. This approach seems to be safe and effective, although more data from randomized trials are needed.
PMID: 31139217 [PubMed]
Source: Journal of Contemporary Brachytherapy - May 31, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Hybrid optimization based on non-coplanar needles for brachytherapy dose planning.
Conclusions: The hybrid inverse optimization method achieved high conformity in the clinical practice. The non-coplanar needle can help to achieve a better dose distribution than the coplanar needle.
PMID: 31435434 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 24, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Influence of dwell time homogeneity error weight parameter on treatment plan quality in inverse optimized high-dose-rate cervix brachytherapy using SagiPlan.
Conclusions: Assuming a static geometry, statistically significant degradation of plan quality can result from restricting the dwell time homogeneity in min/max-based optimization of cervix HDR brachytherapy plans using SagiPlan. Therefore, setting DTHEW to zero is indicated for the type of patient plans considered in this study.
PMID: 31435433 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 24, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Fibre-optic endoscope-guided three-dimensional high-dose-rate interstitial brachytherapy for residual nasopharyngeal carcinoma after conventional external beam radiotherapy.
Conclusions: Fibre-optic endoscope-guided 3D HDR ISBT boost could be an additional treatment strategy for locoregional residual NPC after radical EBRT, especially for deep invasive lesion.
PMID: 31435431 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 24, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Complications and adverse events of plaque brachytherapy for ocular melanoma.
This article reviews complications and adverse events of plaque brachytherapy, including scleral necrosis, strabismus, cataract, glaucoma, and retinopathies as well as management of these conditions. For practicing oncologists and ophthalmologists, these complications are important to understand, identify, and treat. Additionally, an understanding of common complications of brachytherapy should influence the decision of pursuing it as a treatment option.
PMID: 31523242 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 17, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Experience in multicatheter interstitial high-dose-rate breast brachytherapy: dose-volume histogram analysis of the first results.
Conclusions: This study is the first stage of the dosimetric evaluation of a new method. The analysis allows treating complex localizations of the breast cancer, for example, in a close position to the skin or ribs. In order to minimize the toxic effects, it is necessary to consider patient selection, catheter administration, and dose optimization.
PMID: 31523236 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 17, 2019 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
