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Total 4460783 results found since Jan 2013.

High-dose-rate interstitial brachytherapy for female peri-urethral cancer.
CONCLUSIONS: Though small sample size, the results of our study have shown that HDR-IBT provides good loco-regional control with acceptable toxicity for female PUC. PMID: 26985196 [PubMed]
Source: Journal of Contemporary Brachytherapy - March 18, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer.
CONCLUSIONS: Brachytherapy boost is associated with a decreased rate of PCSM in some men with high-risk prostate cancer but not among patients with favorable high-risk disease. Our results suggest that the recently-defined "favorable high-risk" category may be used to personalize therapy for men with high-risk disease. PMID: 26985191 [PubMed]
Source: Journal of Contemporary Brachytherapy - March 18, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Impact of heterogeneity-corrected dose calculation using a grid-based Boltzmann solver on breast and cervix cancer brachytherapy.
CONCLUSIONS: Lower doses were reported when calculating with Acuros compared to TG-43. Differences in dose parameters were larger in breast cases. A lower impact on clinical dose parameters was found for the cervix cases. Applicator material causes systematic shielding effects that can be taken into account. PMID: 27257419 [PubMed]
Source: Journal of Contemporary Brachytherapy - June 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image guided radiation therapy boost in combination with high-dose-rate intracavitary brachytherapy for the treatment of cervical cancer.
CONCLUSIONS: B + I can improve dose distribution in cervical cancer treatment; it could be useful for tumors extended beyond the reach of intracavitary/interstitial brachytherapy (IC/ISBT) or for centers that are inexperienced or ill-equipped with IC/ISBT techniques. Additional confirmatory prospective studies with larger numbers of patients and longer follow-up are required to validate the durability. PMID: 27257416 [PubMed]
Source: Journal of Contemporary Brachytherapy - June 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Multi-catheter interstitial brachytherapy for partial breast irradiation: an audit of implant quality based on dosimetric evaluation comparing intra-operative versus post-operative placement.
CONCLUSIONS: Critical evaluation of the dosimetric parameters of MIB-APBI is important for optimal results. While the open and closed techniques have similar dosimetry, our institutional preference is for an open technique which eases the procedure due to direct visualization of the tumor cavity. PMID: 27257415 [PubMed]
Source: Journal of Contemporary Brachytherapy - June 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Prostate-specific antigen nadir after high-dose-rate brachytherapy predicts long-term survival outcomes in high-risk prostate cancer.
CONCLUSIONS: A post-radiotherapy nPSA value of ≤ 0.02 ng/ml was associated with better long-term biochemical tumor control even if patients had pretreatment predictive values for worse control. PMID: 27257412 [PubMed]
Source: Journal of Contemporary Brachytherapy - June 5, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Image-guided high-dose-rate brachytherapy of malignancies in various inner organs - technique, indications, and perspectives.
This article reviews technical properties of image-guided brachytherapy, indications and its current clinical role in multimodal cancer treatment. Furthermore, perspectives of this novel therapy option will be discussed. PMID: 27504135 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Single fraction multimodal image guided focal salvage high-dose-rate brachytherapy for recurrent prostate cancer.
CONCLUSIONS: Single fraction, focal, multimodal image guided salvage HDR brachytherapy for recurrent prostate cancer is a feasible therapy for selected patients with single lesions. This approach has to be evaluated in larger clinical trials. PMID: 27504134 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Potential role of TRAns Cervical Endosonography (TRACE) in brachytherapy of cervical cancer: proof of concept.
CONCLUSIONS: Present proof of concept demonstrates potential role of TRACE-BT for cervical cancer as an attractive high-tech approach with reasonable costs. Prior to investigation of its clinical role, further development of TRACE methodology is needed. This includes reliable transducer-tissue coupling, applicator reconstruction, imaging range, limitations in extensive tumors, US-based contouring concepts, registration with other imaging methods, organ dose-assessment, real-time dosimetry, etc. PMID: 27504131 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Robustness of IPSA optimized high-dose-rate prostate brachytherapy treatment plans to catheter displacements.
CONCLUSIONS: The results indicate that if used in conjunction with a pre-treatment catheter displacement correction protocol and a tolerance of 3 mm, a DTDC value of 0.4 may produce clinically superior plans. However, the effect of the DTDC parameter in plan robustness was not observed to be as strong as initially suspected. PMID: 27504129 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Highly conformal CT based surface mould brachytherapy for non-melanoma skin cancers of earlobe and nose.
CONCLUSIONS: Computed tmography-based surface mould brachytherapy for superficial lesions on irregular surfaces is a highly conformal method with good homogeneity. Brachytherapy is superior to EBRT in those locations in terms of conformity and normal tissue sparing ability in high doses. PMID: 27504128 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Clinical comparison of brachytherapy versus hypofractionated external beam radiation versus standard fractionation external beam radiation for non-melanomatous skin cancers.
CONCLUSIONS: All modalities investigated represent effective treatments for NMSC and have good cosmetic outcomes and acceptable toxicity profiles. The finding of higher grade toxicity and a greater portion of patients experiencing toxicity among standard fractionation therapy is counter to expectations. There was no statistical significance to the finding and it is not likely to be meaningful. PMID: 27504127 [PubMed]
Source: Journal of Contemporary Brachytherapy - August 11, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Metal artefacts in MRI-guided brachytherapy of cervical cancer.
Authors: Soliman AS, Owrangi A, Ravi A, Song WY Abstract The importance of assessing the metal-induced artefacts in magnetic resonance imaging (MRI)-guided brachytherapy is growing along with the increasing interest of integrating MRI into the treatment procedure of cervical cancer. Examples of metal objects in use include intracavitary cervical applicators and interstitial needles. The induced artefacts increase the uncertainties in the clinical workflow and can be a potential obstacle for the accurate delivery of the treatment. Overcoming this problem necessitates a good understanding of its originating sources. ...
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Novel simple templates for reproducible positioning of skin applicators in brachytherapy.
CONCLUSIONS: The template La Fe-ITIC is simple and practical. It improves both the set-up time and reproducibility. It helps to establish the adequate margins, an essential point in the clinical outcome. PMID: 27648089 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy).
CONCLUSIONS: Setting up a consortium is a feasible and practicable tool in the creation of an international and multi-system data sharing system. COBRA C-SS seems to be well accepted by all involved parties, primarily because it does not influence the center's own data storing technologies, procedures, and habits. Furthermore, the method preserves the privacy of all patients. PMID: 27648088 [PubMed]
Source: Journal of Contemporary Brachytherapy - September 22, 2016 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research