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Total 4460783 results found since Jan 2013.
Efficacy and safety of image-guided interstitial single fraction high-dose-rate brachytherapy in the management of metastatic malignant melanoma.
CONCLUSIONS: Image-guided HDR brachytherapy is a safe and effective treatment procedure in metastatic malignant melanoma.
PMID: 26034497 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Is there a subset of patients with recurrent cancer in the vagina who are not candidates for interstitial brachytherapy that can be treated with multichannel vaginal brachytherapy using graphic optimization?
CONCLUSIONS: MVC-based VBT using graphic optimization is safe and yields favorable results if used judiciously.
PMID: 26034494 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Modern head and neck brachytherapy: from radium towards intensity modulated interventional brachytherapy.
Authors: Kovács G
Abstract
Intensity modulated brachytherapy (IMBT) is a modern development of classical interventional radiation therapy (brachytherapy), which allows the application of a high radiation dose sparing severe adverse events, thereby further improving the treatment outcome. Classical indications in head and neck (H&N) cancers are the face, the oral cavity, the naso- and oropharynx, the paranasal sinuses including base of skull, incomplete resections on important structures, and palliation. The application type can be curative, adjuvant or perioperative, as a boost to external beam radiation as we...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Single versus multichannel applicator in high-dose-rate vaginal brachytherapy optimized by inverse treatment planning.
CONCLUSIONS: Vaginal HDR brachytherapy using a multichannel vaginal applicator and inverse planning provides dosimetric advantages over single channel cylinder, by reducing the dose to organs at risk without compromising the target volume coverage, but at the expense of an increased vaginal mucosa dose. Due to large inter-fraction dose variations, we recommend individual fraction treatment plan optimization.
PMID: 25834580 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
University Cooperation Platform (UCP) between Christian-Albrechts-University Kiel (Germany) and Chiang Mai University (Thailand): implementation of image-guided gynecological brachytherapy.
In conclusion, analyses revealed excellent results for the high-dose-rate IGBT in patients with advanced gynecological cancer both by using CT and MRI, and/or the combination with WP-IMRT. They also define MRI as gold standard for soft tissue assessment and to determine more accurately HR-CTV. The use of TAUS-guidance adds quality aspects to the "classical" conventional X-ray based planning, especially in terms of real-time measures and adequate soft tissue information, and may lower significantly the dose in OARs. The review of all UCP-results reconfirms the importance of the established program that will continue to oper...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Uterine perforation and its dosimetric implications in cervical cancer high-dose-rate brachytherapy.
CONCLUSIONS: We report a low incidence of uterine perforation and sub-serosal insertion of uterine tandem in intracavitary HDR brachytherapy for cervical cancer. However, the effects on treatment plan dosimetry can be considerably detrimental. Therefore, we recommend image-guided insertion, at least for the challenging cases.
PMID: 25829936 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
High-dose-rate brachytherapy delivered in two fractions as monotherapy for low-risk prostate cancer.
CONCLUSIONS: High-dose-rate brachytherapy administered as monotherapy for prostate cancer proved to be a safe alternative treatment for patients with low-risk prostate cancer. Urinary toxicity was associated with the dose administered to 1 cc and 0.1 cc of the urethra and was remarkably inferior to the reported toxicity in similar studies.
PMID: 25829931 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Brachytherapy in India - a long road ahead.
Authors: Banerjee S, Mahantshetty U, Shrivastava S
Abstract
Brachytherapy can play a very important role in the definitive cure by radiation therapy in India. However, except for in a handful of centres, the majority of hospitals use it only for intracavitary treatment. The most probable reasons for such are the lack of logistical resources in terms of trained personal and supporting staff, rather than lack of radiotherapy machines and equipment. In this article, the authors look into the various aspects of brachytherapy in India: from its beginning to present days. The authors point out the resources available, sh...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Mapping of dose distribution from IMRT onto MRI-guided high dose rate brachytherapy using deformable image registration for cervical cancer treatments: preliminary study with commercially available software.
CONCLUSIONS: This study reveals that deformed EBRT dose distribution to HR-CTV and OARs in MR images for brachytherapy is technically feasible, and achieves differences compared to a uniform dose distribution. Therefore, the assumption that EBRT contributes the same dose value may need to be carefully investigated further based on deformable image registration.
PMID: 25097559 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Effect of tissue composition on dose distribution in brachytherapy with various photon emitting sources.
CONCLUSIONS: The ignorance of soft tissue characteristics (density, composition, etc.) by treatment planning systems incorporates a significant error in dose delivery to the patient in brachytherapy with photon sources. The error depends on the type of soft tissue, brachytherapy source, as well as the distance from the source.
PMID: 24790623 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Iodine-125 prostate seed brachytherapy in renal transplant recipients: an analysis of oncological outcomes and toxicity profile.
CONCLUSIONS: (125)I prostate seed brachytherapy is associated with high rates of biochemical control and minimal toxicity to the renal graft in RTRs. This treatment should be considered as an alternative to surgery in managing RTRs with localized prostate cancer.
PMID: 24790617 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Prostate-specific antigen bounce predicts for a favorable prognosis following brachytherapy: a meta-analysis.
CONCLUSIONS: Our meta-analysis determined that PSA bounce predicts for improved biochemical control following brachytherapy. To our knowledge, this is the first study describing this effect.
PMID: 24474969 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Superficial ocular malignancies treated with strontium-90 brachytherapy: long term outcomes.
CONCLUSIONS: Strontium-90 brachytherapy used in early invasive conjunctival malignancies as an adjunct to surgery in primary and recurrent settings, results in optimal disease control and ocular functional outcomes.
PMID: 26622243 [PubMed - as supplied by publisher]
Source: Journal of Contemporary Brachytherapy - December 5, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
MITHRA - multiparametric MR/CT image adapted brachytherapy (MR/CT-IABT) in anal canal cancer: a feasibility study.
CONCLUSIONS: Brachytherapy is a possible option in anal cancer radiotherapy to perform the boost to complete external beam radiotherapy (EBRT). Magnetic resonance can also have biological advantages compared to the US. Our results suggest that the multiparametric MR/CT-IABT for anal cancer is feasible and safe. This new approach paves the way to prospective comparison studies between MRI and ultrasound-guided brachytherapy (USBT) in anal canal cancer.
PMID: 26622238 [PubMed - as supplied by publisher]
Source: Journal of Contemporary Brachytherapy - December 5, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Brachytherapy for malignancies of the vagina in the 3D era.
Authors: Glaser SM, Beriwal S
Abstract
Vaginal cancer is an uncommon malignancy and can be either recurrent or primary. In both cases, brachytherapy places a central role in the overall treatment course. Recent technological advances have led to more advanced brachytherapy techniques, which in turn have translated to improved outcomes for patients with malignancies of the vagina. The aim of this manuscript is to outline the incorporation of modern brachytherapy into the treatment of patients with vaginal cancer including patient selection along with the role of brachytherapy in conjunction with other treatment moda...
Source: Journal of Contemporary Brachytherapy - December 5, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
