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Total 4460783 results found since Jan 2013.

Distinguishing prostate-specific antigen bounces from biochemical failure after low-dose-rate prostate brachytherapy.
CONCLUSIONS: Although there is substantial overlap between the features of benign PSA bounces and failure, physicians may find it useful to evaluate the timing, absolute PSA level, initial response to treatment, and rate of rise when contemplating management for a PSA rise after low-dose-rate brachytherapy. PMID: 25337125 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Breast conservation therapy without capsular contracture in young augmented women using interstitial brachytherapy.
CONCLUSIONS: A technique of reliable and reproducible accelerated partial breast irradiation is described that minimizes the risk of capsular contracture by avoiding circumferential dose to the foreign body in the breast. PMID: 25097566 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Potential role of ultrasound imaging in interstitial image based cervical cancer brachytherapy.
Authors: Kamrava M Abstract In 2012, more than 500,000 cases of cervical cancer were diagnosed worldwide. Over three quarters of these cases occur in less developed countries [1]. Advancements in image-guided brachytherapy are resulting in improved outcomes and reduced morbidity for women with this disease, but its worldwide adoption is hampered by lack of accessibility to advanced imaging techniques. Ultrasound is emerging as a potential option for tumor visualization, brachytherapy catheter placement, and treatment planning. While additional work is needed, ultrasound can potentially serve as the sole imaging mod...
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dose estimation for different skin models in interstitial breast brachytherapy.
CONCLUSIONS: Monitoring of doses received by skin is necessary to avoid complications and obtain a satisfactory cosmetic effect. It is difficult to assess the compatibility of treatment plans with recommendations, while there is no unambiguous way of skin contouring. Especially, if a mean difference of doses between two models of skin contouring is 18% for the most exposed 0.1 cc and can reach almost 28% in some cases. Differences of this magnitude can result in skin complications during BCT. PMID: 25097562 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Bladder preservation with brachytherapy compared to cystectomy for T1-T3 muscle-invasive bladder cancer: a systematic review.
CONCLUSIONS: Robustness of the analysis is hampered by the retrospective character of the study and differences in patient characteristics. For selected cases, bladder sparing by brachytherapy leads to at least similar overall survival compared to radical cystectomy for muscle invasive bladder cancer. PMID: 25097561 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Catheter displacement prior to the delivery of high-dose-rate brachytherapy in the treatment of prostate cancer patients.
CONCLUSIONS: Our results indicate that catheter positions must be confirmed and if required, adjusted, prior to every treatment fraction for the precise treatment delivery of HDR brachytherapy, and to potentially reduce over-dosage to the bulbo-membranous urethra. PMID: 25097556 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Impact of intraoperative MRI/TRUS fusion on dosimetric parameters in cT3a prostate cancer patients treated with high-dose-rate real-time brachytherapy.
CONCLUSIONS: TRUS/MRI fusion provides important information for prostate brachytherapy, allowing for better coverage and higher doses to extracapsular disease in patients with clinical stage T3a. PMID: 25097555 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

High-dose-rate brachytherapy as monotherapy for prostate cancer: technique, rationale and perspective.
Authors: Yoshioka Y, Suzuki O, Otani Y, Yoshida K, Nose T, Ogawa K Abstract High-dose-rate (HDR) brachytherapy as monotherapy is a comparatively new brachytherapy procedure for prostate cancer. Although clinical results are not yet mature enough, it is a highly promising approach in terms of potential benefits for both radiation physics and radiobiology. In this article, we describe our technique for monotherapeutic HDR prostate brachytherapy, as well as the rationale and theoretical background, with educational intent. PMID: 24790627 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Day to day treatment variations of accelerated partial breast brachytherapy using a multi-lumen balloon.
CONCLUSIONS: Overall, APBI treatments with MLB based brachytherapy are precise from day to day. However, minor variation due to daily treatment uncertainties can still degrade tumor bed coverage to an unacceptable coverage when V95 of the original plan is close to 90%. PMID: 24790624 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Dummy source digitization algorithm for reconstruction of flexible brachytherapy catheters with biplane images.
CONCLUSIONS: THE DUMMY SOURCE COORDINATES ON THE BIPLANE IMAGES WERE DIGITIZED IN A PROPER SEQUENCE: from the catheters' tip towards the end of the catheters. After the three-dimensional reconstruction of the catheters from the digitized coordinates, the geometry file was imported by the brachytherapy planning system for dose calculation. The method has the advantage to eliminate manual digitization of the dummy sources. PMID: 24790621 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Optimal single 3T MR imaging sequence for HDR brachytherapy of cervical cancer.
CONCLUSIONS: There was little difference between 2D and 3D-based scanning sequences; however the increased scanning time of 3D sequences have potential to introduce greater patient motion artifacts. A contiguous 2D sequence based on an axial T2-weighted turbo-spin-echo (TSE) sequence orientated in all planes of the treatment applicator provided consistent tumour delineation whilst allowing applicator reconstruction and treatment planning. PMID: 24790615 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Bilateral episcleral brachytherapy in simultaneous choroidal melanoma and circumscribed hemangioma.
CONCLUSIONS: Bilateral episcleral brachytherapy successfully treated both tumors, preserving the eyes and useful visual function. PMID: 24474976 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

New (125)I brachytherapy source IsoSeed I25.S17plus: Monte Carlo dosimetry simulation and comparison to sources of similar design.
CONCLUSIONS: Results are presented in the form of the quantities defined in the update of the Task Group 43 report, as well as a relative dose rate table in Cartesian coordinates. The dose rate distribution of the new source is comparable to that of sources of similar design (IsoSeed I25.S17, Oncoseed 6711, SelectSeed 130.002, Advantage IAI-125A, I-Seed AgX100, Thinseed 9011). Noticeable differences were observed only for the IsoSeed I25.S06 and Best 2301 sources. PMID: 24474975 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Head and neck (192)Ir HDR-brachytherapy dosimetry using a grid-based Boltzmann solver.
CONCLUSIONS: Dose differences between results of a grid-based Boltzmann solver and TG-43 formalism for high-dose-rate head and neck brachytherapy patients to the target volume were found. Distinctions in D90 of CTV were low (2.63 Gy for grid-based Boltzmann solver vs. 2.71 Gy TG-43 in mean). In our clinical practice, prescription doses remain unchanged for high-dose-rate head and neck brachytherapy for the time being. PMID: 24474973 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

Three-dimensional dosimetric considerations from different point A definitions in cervical cancer low-dose-rate brachytherapy.
CONCLUSIONS: Different point A definitions lead to significant dose differences. Careful consideration should be given when changing practice from one point A definition to another, to ensure dosimetric and clinical equivalency from the previous clinical experiences. PMID: 24474971 [PubMed]
Source: Journal of Contemporary Brachytherapy - November 18, 2015 Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research