• Filter By:

Risk Factors for Breast Cancer-Related Lymphedema: An Umbrella Review
CONCLUSIONS: The currently identified risk factors for BCRL all are innate personal trait-related factors. Future well-designed studies and robust meta-analyses are needed to explore potential associations between behavioral-, interpersonal-, and environmental-related factors and BCRL, as well as the role of genetic variations and pathophysiologic factors.PMID:37725224 | DOI:10.1245/s10434-023-14277-7
Source: Ann Oncol - September 19, 2023 Category: Cancer & Oncology Authors: Aomei Shen Wanmin Qiang Liyuan Zhang Jingru Bian Fei Zhu Zijuan Zhang Qian Lu Source Type: research

Proteomic landscape of primary and metastatic brain tumors for heterogeneity discovery
CONCLUSIONS AND CLINICAL RELEVANCE: We characterized an extensive proteomic landscape of BrMs and gliomas. These findings have promising implications for the development of targeted therapies for BrMs and gliomas.PMID:37726528 | DOI:10.1002/prca.202300010
Source: Clinical Genitourinary Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Shuang Yang Chengbin Zhou Lei Zhang Yueting Xiong Yongtao Zheng Liuguan Bian Xiaohui Liu Source Type: research

Systematic Minigene-Based Splicing Analysis and Tentative Clinical Classification of 52 CHEK2 Splice-Site Variants
CONCLUSIONS: Incorporation of minigene read-outs into an ACMG/AMP (American College of Medical Genetics and Genomics/Association for Molecular Pathology)-based classification scheme allowed us to classify 32 CHEK2 variants (27 pathogenic/likely pathogenic and 5 likely benign). However, 20 variants (38%) remained of uncertain significance, reflecting in part the complex splicing patterns of this gene.PMID:37725924 | DOI:10.1093/clinchem/hvad125
Source: Clinical Genitourinary Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Lara Sanoguera-Miralles Alberto Valenzuela-Palomo Elena Bueno-Mart ínez Ada Esteban-S ánchez V íctor Lorca In és Llinares-Burguet Alicia Garc ía-Álvarez Pedro P érez-Segura Mar Infante Douglas F Easton Peter Devilee Maaike P G Vreeswijk Miguel de l Source Type: research

Secondary Breast Angiosarcoma After a Primary Diagnosis of Breast Cancer: A Retrospective Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
CONCLUSIONS: We demonstrate an increasing incidence of SBA over the study period. These data can help inform shared decision-making for optimal management of locoregional breast cancer and raise awareness of secondary angiosarcoma.PMID:37725702 | DOI:10.1097/COC.0000000000001045
Source: Clinical Genitourinary Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Bonny Chau Elizabeth T Loggers Lee D Cranmer Harveshp Mogal Jeremy M Sharib Edward Y Kim Stephanie K Schaub Kelly G Paulson Hannah M Linden Jennifer M Specht Janice N Kim Sara H Javid Michael J Wagner Source Type: research

RANK expression as an independent predictor for response to neoadjuvant chemotherapy in luminal-like breast cancer - a translational insight from the GeparX trial
CONCLUSIONS: We report RANK expression to be an independent predictive biomarker for response to NACT in luminal-like breast cancer patients.PMID:37725572 | DOI:10.1158/1078-0432.CCR-23-1801
Source: Clinical Genitourinary Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Theresa Link Jens-Uwe Blohmer Wolfgang D Schmitt Jan Dominik Kuhlmann Marianne Just Michael Untch Oliver Stotzer Peter A Fasching Marc Thill Mattea Reinisch Andreas Schneeweiss Pauline Wimberger Sabine Seiler Jens Huober Christian Jackisch Kerstin Rhiem C Source Type: research

Twenty-Year Follow-Up of a Phase II Trial of Taxotere/Carboplatin/Herceptin in Patients With Metastatic HER2-Positive Breast Cancer
CONCLUSION: A subset of patients (10%) receiving trastuzumab in the metastatic setting have achieved long-term survival beyond 20 years.PMID:37725049 | DOI:10.1093/oncolo/oyad258
Source: The Oncologist - September 19, 2023 Category: Cancer & Oncology Authors: Juan Luis Gomez Marti Azadeh Nasrazadani Ying Ding Daniel Normolle Adam M Brufsky Source Type: research

Experimental study of HIFU incomplete ablation on the damage effect and prognosis of rabbit VX2 breast cancer model
CONCLUSIONS: HIFU incomplete ablation, with an 80% tumor ablation rate, induces substantial tumor damage, augments tumor cell apoptosis, and triggers an anti-tumor immune response, curtailing metastasis. These insights may underpin further investigations into the therapeutic implications of HIFU incomplete ablation.PMID:37726101 | DOI:10.1080/02656736.2023.2255760
Source: International Journal of Hyperthermia - September 19, 2023 Category: Internal Medicine Authors: Xiaoling Feng Min Yang Jianhu Li Hongjian Liao Zhifei Zhang Qi Wang Yonghong Du Source Type: research

Design and Synthesis of New bis-oxindole and Spiro(triazole-oxindole) as CDK4 Inhibitors with Potent Anti-breast Cancer Activity
CONCLUSION: According to all of the findings, bis-oxindole 3c shows promise as a cancer treatment targeting CDK4.PMID:37723960 | DOI:10.2174/1573406419666230810124855
Source: Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Thoraya A Farghaly Rami Adel Pashameah Abrar Bayazeed Amerah M Al-Soliemy Amani M R Alsaedi Marwa F Harras Source Type: research

Proteomic landscape of primary and metastatic brain tumors for heterogeneity discovery
CONCLUSIONS AND CLINICAL RELEVANCE: We characterized an extensive proteomic landscape of BrMs and gliomas. These findings have promising implications for the development of targeted therapies for BrMs and gliomas.PMID:37726528 | DOI:10.1002/prca.202300010
Source: Clinical Colorectal Cancer - September 19, 2023 Category: Cancer & Oncology Authors: Shuang Yang Chengbin Zhou Lei Zhang Yueting Xiong Yongtao Zheng Liuguan Bian Xiaohui Liu Source Type: research

Accessory breast cancer: A case report and literature review of ultrasonographic findings
Australas J Dermatol. 2023 Sep 18. doi: 10.1111/ajd.14160. Online ahead of print.NO ABSTRACTPMID:37723873 | DOI:10.1111/ajd.14160
Source: The Australasian Journal of Dermatology - September 19, 2023 Category: Dermatology Authors: Kazuki Ichihashi Akimasa Adachi Yasuyuki Sawada Source Type: research

The quality and clinical translation of radiomics studies based on MRI for predicting Ki-67 levels in patients with breast cancer
CONCLUSION: Ki-67 index is a common tumor biomarker with high clinical value. Radiomics is an ever-growing quantitative data-mining method helping predict tumor biomarkers from medical images. However, the quality of the reviewed studies evaluated by the RQS was not so satisfactory and there are ample opportunities for improvement. Open science and data, external validation, phantom study, publicly open radiomics database and standardization in the radiomics practice are what researchers should pay more attention to in the future.ADVANCES IN KNOWLEDGE: The RQS tool considered the radiomics used to predict the Ki-67 level w...
Source: The British Journal of Radiology - September 19, 2023 Category: Radiology Authors: Min Wang Ting Mei Youling Gong Source Type: research

Accessory breast cancer: A case report and literature review of ultrasonographic findings
Australas J Dermatol. 2023 Sep 18. doi: 10.1111/ajd.14160. Online ahead of print.NO ABSTRACTPMID:37723873 | DOI:10.1111/ajd.14160
Source: The Australasian Journal of Dermatology - September 19, 2023 Category: Dermatology Authors: Kazuki Ichihashi Akimasa Adachi Yasuyuki Sawada Source Type: research

Anti ‐aquaporin‐4 immunoglobulin G/anti‐myelin oligodendrocyte glycoprotein immunoglobulin G double‐positive paraneoplastic neurological syndrome in a patient with triple‐negative breast cancer
We report a rare case of paraneoplastic neurological syndrome with dual seropositivity of anti-aquaporin-4 and myelin oligodendrocyte glycoprotein antibodies in a 40  year-old woman with metastatic triple-negative breast cancer. She received multiple lines of anti-neoplastic treatment, including immunotherapy with pembrolizumab, as well as cytotoxic chemotherapy. Paraneoplastic meningoencephalomyelitis developed 2 years after diagnosis of breast cancer and 1  year after discontinuation of immunotherapy with pembrolizumab. She first developed longitudinally extending transverse myelitis followed by left optic neuritis...
Source: Clinical and Experimental Neuroimmunology - September 19, 2023 Category: Neurology Authors: Amna Siddiqui, Dylan Ross, Ronak H. Jani, Vikram C. Prabhu, Shelly Lo, Derek A. Wainwright, Stasia Rouse, Tamer Refaat, Yirong Zhu, Jigisha P. Thakkar Tags: CASE REPORT Source Type: research

The Relationship between Metformin Consumption and Cancer Risk: An Updated Umbrella Review of Systematic Reviews and Meta ‑Analyses
Conclusions: Treatment with metformin can significantly decrease the chance of all cancers with larger preventive effect on hepatocellular carcinoma and smaller preventive effect on lung and breast cancers.
Source: International Journal of Preventive Medicine - September 19, 2023 Category: International Medicine & Public Health Source Type: research

Clinical and pathological factors and outcome of central nervous system metastasis in breast cancer
This study aimed to identify prognostic factors for overall survival (OS) in a cohort of Swiss patients with BMBC. This study evaluated the prognosis on older BMBC, which has not been completely addressed in the literature.MethodsWe performed a retrospective chart review analysis with the primary endpoint of OS after a diagnosis of BMBC. The study population was divided into 2 groups based on an OS cut-off value of 12 months after diagnosis. Univariate and multivariate analyses of several risk factors, including age, were performed. To evaluate differences in OS according to age, we performed a secondary analysis to examin...
Source: Frontiers in Oncology - September 19, 2023 Category: Cancer & Oncology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20