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Infant Dies Following 5 Vaccine Doses
Life after losing a loved one to vaccines is very painful. With a heavy heart, we share Sebastian Ryan Morley’s story. He was a healthy boy whose life ended after routine vaccinations. Sebastian’s mother and grandmother have worked many years in both the veterinary and human healthcare fields. What they were taught in school led them to believe vaccines were safe, but now they will never vaccinate again. We thank his family for coming forward and sharing very important information the public isn’t usually made aware of. Sebastian’s grandmother, Valerie Murfin, shared: “On December 11, 2002, when my grandson Sebas...
Source: vactruth.com - September 5, 2015 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Human Top Stories adverse reactions dtap Hepatitis B vaccine Sebastian Ryan Morley truth about vaccines Vaccine Death vaccine injury VAERS Valerie Murfin Source Type: blogs

Chimeric Antigen Receptor T-cells versus Solid Tumors
The future of cancer research is targeting, meaning the ability to destroy cancer cells efficiently and with few to no side-effects on normal tissues. Chimeric antigen receptor (CAR) T-cells are a step forward in this regard, and have proven to be an effective treatment for leukemia in trials. Researchers are now attempting to adapt their use to other types of cancer. In this example, the T-cells are engineered to make them more discriminating when targeted at solid tumors: Many solid cancers have high levels of certain proteins such as ErbB2 and EGFR, which make them suitable targets for anticancer therapies. However, su...
Source: Fight Aging! - September 1, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Why Your Doctor Is Thinking About Getting an MBA
By DAVID SHAYWITZ, MD To understand why so many medical students (and pre-meds) (and doctors) contemplate business training, let’s consider two real-life examples: Dr. Bob Kocher and Dr. Bijan Salehizadeh. Both trained as physicians, both are currently healthcare investors, and both shared their stories with Lisa Suennen and me on our Tech Tonics podcast. (Kocher’s interview can be found here; Salehizadeh’s will available at the end of the month.) (My usual disclosure: I work at a cloud genomics company in Silicon Valley; neither my company nor I have a financial relationship with Kocher, Salehizadeh, or their firms....
Source: The Health Care Blog - August 26, 2015 Category: Consumer Health News Authors: John Irvine Tags: THCB Source Type: blogs

Children with cancer are the real superheroes
Recently I met a boy, a boy with leukemia, a young boy with comic-book worthy superpowers. This boy, this superhero, is one I will never, never forget. When I entered the exam room, I was immediately struck by the sight of a young boy who should have been playing football with his friends at the park or jumping off the high-dive at the pool, but instead was curled up in bed with yet another cancer-related illness. Instead of seeing a seriously ill child, however, I saw a fighter, a Winston Churchill never-give-upper, a battle-beaten-but-war-fighting-combat-warrior, and at his side, his mother-faithful, determined, and ...
Source: Kevin, M.D. - Medical Weblog - August 6, 2015 Category: Journals (General) Authors: Tags: Physician Cancer Pediatrics Source Type: blogs

There are only 3 ways to allocate health care resources
Manny Alvarez is a 23-year-old college student with the misfortune of having not just a devastating cancer — but the wrong devastating cancer. The chemotherapeutic agents shown to be highly active against his specific tumor cells are FDA approved for the treatment of leukemia, but not for the stunningly rare kind of sarcoma with which Manny has been diagnosed. Nothing is FDA approved, or standard care, for the stunningly-rare cancer with which Manny has been diagnosed. That potentially effective drugs have been identified at all is thanks to Manny’s exemplary oncologist, Dr. Breelyn Wilky at the University of M...
Source: Kevin, M.D. - Medical Weblog - July 8, 2015 Category: Journals (General) Authors: Tags: Policy Health reform Source Type: blogs

Debunking Myths About 'Big Pharma'
We recently wrote about the media’s coverage of the 2013 Open Payments data, noting the ease in which a government database emboldens journalists to imply misconduct. Although the Justice Department has not used information from the database to bring forward specific legal action in court, the media has not been as restrained, quickly moving to try their own cases in the “court of public opinion”. These stories create a chilling effect on industry-physician collaboration, as many interactions could subject either party to unwanted—and perhaps more importantly—unjustified attention. These stories nearly universall...
Source: Policy and Medicine - June 10, 2015 Category: American Health Authors: Thomas Sullivan Source Type: blogs

Recent Considerations of Stem Cells and the Aging Process
Investigation of the contribution of stem cells to the process of degenerative aging is a flourishing field of research. As we age our stem cell populations gradually cease their activity, spending more time in periods of quiescence, and becoming more damaged by the wear and tear of continued metabolic activity. The principal role of stem cells is to provide a supply of new cells to keep tissues in working order, and diminished supply results in growing frailty and dysfunction. This is one of the causes of disease and death due to aging. There are reasons for optimism, however. The stem cell research field is collectively...
Source: Fight Aging! - June 4, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Searching for the Steamer retroelement in the ocean metagenome
Location of BLAST (tblastn) hits Mya arenaria GagPol (AIE48224.1) vs GOS contigsLast week, I was listening to episode 337 of the podcast This Week in Virology. It concerned a retrovirus-like sequence element named Steamer, which is associated with a transmissible leukaemia in soft shell clams. At one point the host and guests discussed the idea of searching for Steamer-like sequences in the data from ocean metagenomics projects, such as the Global Ocean Sampling expedition. Sounds like fun. So I made an initial attempt, using R/ggplot2 to visualise the results. To make a long story short: the initial BLAST results are not ...
Source: What You're Doing Is Rather Desperate - May 25, 2015 Category: Bioinformatics Authors: nsaunders Tags: bioinformatics statistics cancer clam GOS metagenomics ocean retroelement steamer twiv virus Source Type: blogs

Prenatal care should start before pregnancy
      Dr. Alisa Hideg via @spokesmanreview Anyone thinking about pregnancy, should also be thinking about prenatal care. This care is important for the mother’s health and the health of the child. Whenever possible, it should begin prior to pregnancy. A visit with your health care provider prior to pregnancy to review your immunizations, start a prenatal vitamin with folic acid (which can prevent certain birth defects if begun prior to pregnancy) and otherwise “check in” is always a good idea. Once you are pregnant, regular prenatal care visits during pregnancy are just as important to your baby’s ...
Source: Cord Blood News - May 15, 2015 Category: Perinatology & Neonatology Authors: joyce at mazelabs.com Tags: babies blood disorder brain development Cord Blood medical research parents pregnancy affordable cord blood banking cerebral palsy cord blood banking fees cord blood treatment for Leukemia cord clamping due dates healthy pregnanc Source Type: blogs

To Spur Medical Innovation, Make Corporate Cheaters Pay
The past decade has seen a relatively constant rate of newly approved drugs every year. The number has even jumped in the past few years. Yet, despite such encouraging trends, we are actually facing a crisis in drug innovation today. That is because many of these new products do not offer substantial improvements over already available alternatives. At the same time, novel and effective treatments for many diseases---both rare and common---remain elusive. For example, there is widespread concern over the lack of development of new antibiotics aimed at multidrug-resistant infections. Therapeutic innovation for central nerv...
Source: Health Affairs Blog - April 30, 2015 Category: Health Management Authors: Aaron Kesselheim Tags: Drugs and Medical Technology Health Policy Lab Medicaid and CHIP Medicare corporations Cost FDA legislation Marketing medical innovation Medical Innovation Act NIH Pharma price Source Type: blogs

More from the Grantmakers In Health Annual Conference: Diane Meier on Palliative Care; a Film on Elder Care
This past week, I gave you a brief glimpse of the 2015 GIH Annual Conference in Austin, Texas. Here are two more vignettes from the conference, held in March. Its theme was Pathways to Health. Diane Meier Director of the Center to Advance Palliative Care at the Icahn School of Medicine at Mount Sinai and a past MacArthur Fellow (2008), Diane Meier was another plenary speaker. She commented to the audience of mostly foundation staffers that her body of work and career in palliative care is due to the support of private-sector philanthropy, including more than twenty foundations. Following are just some of the points she...
Source: Health Affairs Blog - April 23, 2015 Category: Health Management Authors: Lee-Lee Prina Tags: Costs and Spending GrantWatch Health Professionals Hospitals Long-term Services and Supports Quality Aging Health Care Delivery Health Philanthropy Home Health Palliative Care Physicians Workforce Source Type: blogs

A transmissible cancer of soft-shell clams
A leukemia-like cancer is killing soft-shell clams along the east coast of North America. The cancer is transmitted between animals in the ocean, and appears to have originated in a single clam as recently as 40 years ago. Hemic neoplasm is a disease of marine bivalves that is characterized by proliferation of morphologically and functionally aberrant hemocytes, the cells that circulate in the circulatory fluid of mollusks. A newly identified LTR retrotransposon called Steamer correlates with neoplastic disease in clams. LTR retrotransposons are DNA sequences in the genome derived from retroviruses. The normal clam geno...
Source: virology blog - April 10, 2015 Category: Virology Authors: Vincent Racaniello Tags: Uncategorized bivalve cancer clam hemocyte hemolymph leukemia mollusk retrotransposon steamer transmissible neoplasm viral virology virus Source Type: blogs

The trick of hope — and the medical decision
Last night, during the intro show for the PBS documentary, Cancer: The Emperor of All Maladies, a Ken Burns film based on the book by Siddhartha Mukherjee, Katie Couric interviews both Ken Burns and Dr. Mukherjee. The moment occurred about 10 minutes into the video. There is a poignant scene in which two young parents struggle with the decision to enroll Olivia, their 17-month-old baby who has leukemia, into a randomized clinical trial to test one treatment over another. When the doctor tells the parents a computer randomization will determine Olivia’s treatment, you see anguish in their faces. They don’t want ...
Source: Dr John M - March 31, 2015 Category: Cardiology Authors: Dr John Source Type: blogs

FDA Approves Sandoz's Zarxio, The First Biosimilar Approved in the U.S.
Today, the Food and Drug Administration approved Zarxio (filgrastim-sndz), the first biosimilar product approved in the U.S. Sandoz, Inc.’s Zarxio is biosimilar to Amgen Inc.’s Neupogen (filgrastim), which was originally licensed in 1991. The approval comes two months after an FDA advisory committee recommended Zarxio as biosimilar to Neupogen for all five of the intended indications.  A biosimilar product is a biological product that is approved based on a showing that it is highly similar to an already-approved biological product, known as a reference product--in this case Neupogen. The biosimilar a...
Source: Policy and Medicine - March 6, 2015 Category: American Health Authors: Thomas Sullivan Source Type: blogs