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Total 341 results found since Jan 2013.
An Impressive Performance in Clearing Cancer from Mice via Immunotherapy
Immunotherapy is a cut above chemotherapy and radiotherapy: at its best, it is significantly more effective and significantly less harmful to the patient. It has still required years, a great deal of funding, and many failures for those best approaches to arise. Nonetheless, the report here is a cheering example for the sizable fraction of us expected to suffer cancer at some point in the years ahead if the condition is not soon brought under medical control. This immunotherapy appears highly effective, and just importantly, adaptable to many types of cancer. This potential for broad application is the most important aspec...
Source: Fight Aging! - February 2, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
EBV and myeloma stem cells. Chapter 3
This study tells us there are two ways in which a virus, nothing more than a “parasite,” can infect its host cell: 1. actively, by causing “a lytic infection characterized by the release of new progeny virus particles, often upon the lysis of the host cell,” (lysis refers to the destruction of a cell, the host cell in this case), or 2. inactively, which occurs when the virus just sleeps, without reproducing itself.
“Reactivation” occurs when a sleeping virus wakes up and reproduces, stimulated by internal or external factors…but that gets into too much detail, so let’s skip that part.
Here’s anot...
Source: Margaret's Corner - January 23, 2018 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll EBV Epstein-Barr myeloma Source Type: blogs
Precision Medicine and the Reinvention of Human Disease (Book Index)
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book ' s index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 198, 220geAcq...
Source: Specified Life - January 23, 2018 Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs
Fight Aging! Newsletter, January 15th 2018
This study is the longest, prospective randomized controlled trial that has documented the physiological effects of supervised, structured exercise training in a group of sedentary but healthy middle-aged adults. The key finding is that 2 years of exercise training performed for at least 30 minutes, 4 to 5 days per week, and including at least 1 high-intensity interval session per week results in a significant reduction in LV chamber and myocardial stiffness. The use of high-resolution, invasively measured LV pressure-volume curves and comparison with an attention control group enhances the confidence in this conclusion. T...
Source: Fight Aging! - January 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Chemotherapeutic Senolytic Drug Candidates
The objective here is a set of tests that anyone can run without the need to involve a physician, as that always adds significant time and expense. Since we are really only interested in the identification of large and reliable effects as the result of an intervention, we can plausibly expect a collection of cheaper and easier measures known to correlate with age to be useful. Once that hill has been climbed, then decide whether or not to go further - don't bite off more than is easy to chew for a first outing.
From an earlier exploration of likely tests, I picked the following items on the basis of a likely connect...
Source: Fight Aging! - January 12, 2018 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
An Approach to Starving Cancer Cells that is Applicable to Many Cancers
This study is very exciting because it sheds light on a new uncharacterized way to treat cancer with very limited toxicity."
Although cancer cells contain REV-ERB proteins, somehow they remain inactive. The researchers used two REV-ERB activators that had already been developed - SR9009 and SR9011 - in studies on a variety of cancer cells, including those from T cell leukemia, breast cancer, colorectal cancer, melanoma, and glioblastoma. In each cell line, treatment with the REV-ERB activators was enough to kill the cells. The same treatment on healthy cells had no effect. "When we block access to these resources, c...
Source: Fight Aging! - January 12, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Your Brain On Cancer
Once you enter cancerland, your brain takes detours all the time. Where do these detours go? BAD PLACES!" Is that a zit? No, of course not. Its a tumor. Must be skin cancer. "" A headache? No, a brain tumor. Dead in 3 months. "" Is that a swollen lymph node? Quick, leukemia or lymphoma, which one? "As you can easily see you brain with cancer goes down the wrong roads. Usually in the middle of the night. Or when your are stuck in traffic by yourself.You start making little deals with yourself. " I ' ll wait a month and see if its still a problem. No, a month? No three weeks. Wait, two weeks. Maybe ten days. Do I have any bl...
Source: Caroline's Breast Cancer Blog - January 11, 2018 Category: Cancer & Oncology Tags: cancer detection fear of cancer living with cancer stress Source Type: blogs
The Price of Progress
By ANISH KOKA, MD
No one knows who Bennie Solis is anymore.
He had the misfortune of being born in the early 1960s marked for death. He had a rare peculiar condition called biliary atresia – a disease defined by the absence of a conduit for bile to travel from his liver to his intestinal tract. Bile acid produced in the liver normally travels to the intestines much like water from a spring travels via ever larger channels to eventually empty into the ocean. Bile produced in the liver with no where to go dams up in the liver and starts to destroy it.
That the liver is a hardy organ was a fact known to the ancient Gree...
Source: The Health Care Blog - January 4, 2018 Category: Consumer Health News Authors: anish_koka Tags: Uncategorized Source Type: blogs
Viruses and Checkpoint Inhibitors Combine to Form an Effective Cancer Treatment
Researchers here demonstrate a combination therapy that is far more effective in destroying a target cancer than either of its components alone. Effective synergies between therapies are discovered at a fairly low rate by the scientific community, which is in part a reflection of their rarity, but also a reflection of the fact that the regulatory system is not set up to encourage the commercial development of combination therapies. The number of trials for such efforts is small in comparison to single therapy tests. There isn't a good response to this observation beyond the usual calls for more freedom and more funding.
...
Source: Fight Aging! - January 4, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Second Constitutional Challenge to Texas Advance Directives Act
Chris Dunn's constitutional challenge to the Texas Advance Directives Act is on appeal to the Texas First District Court of Appeals. An opening brief has not yet been filed.
Meanwhile, in the U.S. Court of Appeals for the Fifth Circuit another case raising similar issues has now been fully briefed. (Emily-Jean Aguocha-Ohakweh v. Harris County Hospital Dist.)
Aphaeus Ohakweh was admitted to Ben Taub Hospital on March 4, 2015, in need of treatment for AML – acute myeloid leukemia – a potentially fatal cancer that interferes with the production of normal red blood cells.
On March 6, 2015, while b...
Source: blog.bioethics.net - December 12, 2017 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs
Hey Watson, Can I Sue You?
By JAYSON CHUNG & AMANDA ZINK
Currently, three South Korean medical institutions – Gachon University Gil Medical Center, Pusan National University Hospital and Konyang University Hospital – have implemented IBM’s Watson for Oncology artificial intelligence (AI) system. As IBM touts the Watson for Oncology AI’s to “[i]dentify, evaluate and compare treatment options” by understanding the longitudinal medical record and applying its training to each unique patient, questions regarding the status and liability of these AI machines have arisen.
Given its ability to interpret data and present treatment op...
Source: The Health Care Blog - December 10, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs
How Long Does Shingles Last In The Elderly?
View Original Article Here: How Long Does Shingles Last In The Elderly?
Shingles is a viral infection that follows a varicella-zoster infection, although it can take decades for symptoms of the secondary disease to emerge. The condition presents as a painful and blistering rash, but it is not life-threatening.
According to the Center for Disease Control, there are nearly one million cases in the United States each year, and almost half of those cases are in older adults over age 60. Some people only see one instance of the illness, while others have recurring symptoms, but 30 percent of Americans will develop shingles at s...
Source: Shield My Senior - December 8, 2017 Category: Geriatrics Authors: Vin Tags: Senior Safety Source Type: blogs
Dendritic cells, miR-29b, and multiple myeloma
Life is very complicated these days. This morning, after consulting with the vet, I discovered that our giardia-ridden kittens will have to undergo a second cycle of treatment, which will begin next week. This means that they will have to spend another month holed up in their luxurious quarantine, poor dears! I am spending almost all of my free time with them…playing with them, feeding them, holding them, cleaning up, sterilizing, and being SUPER CAREFUL whenever I handle anything at all in the quarantine room.
Mind you, it may sound like it, but I’m not complaining. Not at all!!! I mean, just look at that fa...
Source: Margaret's Corner - November 30, 2017 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll curcumin dendritic cells miR-29b myeloma Source Type: blogs
