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The Magseed Injectable Marker: Interview with Eric Mayes, CEO of Endomag
Endomag, a medical technology company based in Cambridge, UK and Austin, Texas, has developed the Magseed, a magnetic injectable marker that can be implanted by a radiologist during an imaging procedure, such as during ultrasound or X-ray mammographi...
Source: Medgadget - March 9, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Ob/Gyn Pathology Radiology Surgery Source Type: blogs

Senolytic Drugs Fail to Kill Cancerous Cells with Senescent Gene Expression Signatures, but a Gene Therapy Succeeds
Some cancerous cells express signatures normally associated with senescent cells, so why not try senolytic compounds against them? This is something of a full circle, given that most of the current senolytic drug candidates were originally characterized and tested as potential chemotherapeutics. The open access paper here is interesting for two points: firstly, that senolytic drugs didn't kill cancerous cells with a senescent signature, and secondly that a suicide gene therapy targeting that signature does work against both normal senescent cells and cancerous cells with a senescent signature. The gene therapy approach rep...
Source: Fight Aging! - March 7, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, February 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - February 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Nanomachines Create Clots Inside Vessels Feeding Cancer Tumors
Researchers from Arizona State University and National Center for Nanoscience and Technology of the Chinese Academy of Sciences have developed a remarkable new way of killing tumors. They’ve developed robot-like nanoscale devices that cling to ...
Source: Medgadget - February 16, 2018 Category: Medical Devices Authors: Editors Tags: Nanomedicine Oncology Source Type: blogs

DNA Machinery that can Sabotage the Blood Supply of Tumors
Researchers have been building simple molecular machines out of DNA for some years now. This approach to molecular machinery is well suited to applications that involve conditional activation based on the proteins present in the surrounding environment; a lot of the necessary functional parts already exist in DNA and just have to be assembled in the right way. The Oisin Biotechnologies cell-killing technology is a smaller example of the type than the approach here, in which sizable DNA containers are constructed. They carry a cargo that will disrupt local blood flow, and are triggered into opening by cancerous cell surface...
Source: Fight Aging! - February 14, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Precision Medicine and Public Health (from Precision Medicine and the Reinvention of Human Disease)
Excerpted fromPrecision Medicine and the Reinvention of Human DiseaseDespite having the most advanced healthcare technology on the planet, life expectancy in the United States is not particularly high. Citizens from most of the European countries and the highly industrialized Asian countries enjoy longer life expectancies than the United States. According to the World Health Organization, the United States ranks 31st among nations, trailing behind Greece, Chile, and Costa Rica, and barely edging out Cuba [42]. Similar rankings are reported by the US Central Intelligence Agency [43]. These findings lead us to infer that acc...
Source: Specified Life - February 6, 2018 Category: Information Technology Tags: cancer cancer vaccines precision medicine prevention public health Source Type: blogs

An Impressive Performance in Clearing Cancer from Mice via Immunotherapy
Immunotherapy is a cut above chemotherapy and radiotherapy: at its best, it is significantly more effective and significantly less harmful to the patient. It has still required years, a great deal of funding, and many failures for those best approaches to arise. Nonetheless, the report here is a cheering example for the sizable fraction of us expected to suffer cancer at some point in the years ahead if the condition is not soon brought under medical control. This immunotherapy appears highly effective, and just importantly, adaptable to many types of cancer. This potential for broad application is the most important aspec...
Source: Fight Aging! - February 2, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How to Cope with a Scary Medical or Mental Health Diagnosis
Most of us are sanguine about the fact that some things are out of our control. We know, for example, that we can’t avoid death or taxes or do much about how tall we’ll grow. For much of everything else, we figure out a way to deal with what happens in life — until we can’t, for one reason or another. A prime example is the emotional upheaval caused by receiving an unexpected and scary medical or mental health diagnosis. Having gone through this myself recently, here are some ways to help you cope. Get all the facts. After the initial shock, take a few deep breaths and resolve to learn as much as you can about ...
Source: World of Psychology - January 29, 2018 Category: Psychiatry & Psychology Authors: Suzanne Kane Tags: Anxiety and Panic Grief and Loss Health-related Inspiration & Hope Motivation and Inspiration Cancer Chronic Illness Coping Skills health scare Medical Care Mental Illness Resilience Source Type: blogs

Precision Medicine and the Reinvention of Human Disease (Book Index)
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book ' s index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 198, 220geAcq...
Source: Specified Life - January 23, 2018 Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs

An Approach to Starving Cancer Cells that is Applicable to Many Cancers
This study is very exciting because it sheds light on a new uncharacterized way to treat cancer with very limited toxicity." Although cancer cells contain REV-ERB proteins, somehow they remain inactive. The researchers used two REV-ERB activators that had already been developed - SR9009 and SR9011 - in studies on a variety of cancer cells, including those from T cell leukemia, breast cancer, colorectal cancer, melanoma, and glioblastoma. In each cell line, treatment with the REV-ERB activators was enough to kill the cells. The same treatment on healthy cells had no effect. "When we block access to these resources, c...
Source: Fight Aging! - January 12, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Your Brain On Cancer
Once you enter cancerland, your brain takes detours all the time. Where do these detours go? BAD PLACES!" Is that a zit? No, of course not. Its a tumor. Must be skin cancer. "" A headache? No, a brain tumor. Dead in 3 months. "" Is that a swollen lymph node? Quick, leukemia or lymphoma, which one? "As you can easily see you brain with cancer goes down the wrong roads. Usually in the middle of the night. Or when your are stuck in traffic by yourself.You start making little deals with yourself. " I ' ll wait a month and see if its still a problem. No, a month? No three weeks. Wait, two weeks. Maybe ten days. Do I have any bl...
Source: Caroline's Breast Cancer Blog - January 11, 2018 Category: Cancer & Oncology Tags: cancer detection fear of cancer living with cancer stress Source Type: blogs

Doctors, Data, Diagnoses, and Discussions: Achieving Successful and Sustainable Personalized/Precision Medicine
The following is a guest blog post by Drew Furst, M.D., Vice President Clinical Consultants at Elsevier Clinical Solutions. Personalized/precision medicine is a growing field and that trend shows no sign of slowing down. In fact, a 2016 Grand View Research report estimated the global personalized medicine market was worth $1,007.88 billion in 2014, with projected growth to reach $2,452.50 billion by 2022. As these areas of medicine become more commonplace, understanding the interactions between biological factors with a range of personal, environmental and social impacts on health is a vital step towards achieving sustaina...
Source: EMR and HIPAA - January 10, 2018 Category: Information Technology Authors: Guest Blogger Tags: Clinical Decision Support Genomics Healthcare HealthCare IT Personalized Medicine Drew Furst Elsevier Elsevier Clinical Solutions Precision Medicine Source Type: blogs

Viruses and Checkpoint Inhibitors Combine to Form an Effective Cancer Treatment
Researchers here demonstrate a combination therapy that is far more effective in destroying a target cancer than either of its components alone. Effective synergies between therapies are discovered at a fairly low rate by the scientific community, which is in part a reflection of their rarity, but also a reflection of the fact that the regulatory system is not set up to encourage the commercial development of combination therapies. The number of trials for such efforts is small in comparison to single therapy tests. There isn't a good response to this observation beyond the usual calls for more freedom and more funding. ...
Source: Fight Aging! - January 4, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Is there a link between alcohol and skin cancer?
Patients are always elated when you can recommend an enjoyable, health-improving, recreational activity. As a runner, my favorite “prescription” while pregnant was exercise! However, more often than not, pleasurable activities are not what’s best for one’s health. But as a dermatologist who specializes in skin cancer, I am generally the bearer of bad news when I tell patients to never get another tan. This November, alcohol came into the spotlight. The Cancer Prevention Committee of the American Society of Clinical Oncology recommended minimizing drinking alcohol, as it is thought to be a “modifiable risk factor ...
Source: Harvard Health Blog - December 8, 2017 Category: Consumer Health News Authors: Emily S. Ruiz, MD, MPH Tags: Cancer Health Healthy Eating Prevention Source Type: blogs

Sensus Healthcare ’s Technology Uses Low-Energy X-rays Directly on Cancer Cells: Interview with CEO Joe Sardano
Sensus Healthcare is a medical device company that focuses on providing non-invasive and cost-effective treatment of non-melanoma skin cancers and keloids utilizing superficial radiation technology (SRT). Their proprietary, FDA-cleared SRT technology...
Source: Medgadget - November 20, 2017 Category: Medical Devices Authors: Alice Ferng Tags: Dermatology Exclusive Oncology Source Type: blogs