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Total 467 results found since Jan 2013.
Microneedle Skin Patch Measures Cancer Biomarkers
Researchers at the Harvard Wyss Institute have developed a technique that lets clinicians to characterize and monitor melanoma. The system involves using a microneedle patch that can draw deep interstitial fluid into itself through a series of penetr...
Source: Medgadget - September 14, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Diagnostics Medicine Oncology harvard wyssinstitute Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem ce...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Transferring the Naked Mole Rat Hyaluronan Synthase 2 Gene Into Mice Reduces Cancer Incidence, Extends Life
Naked mole rats live far longer than similarly sized mammals, and are near immune to cancer. One of the mechanisms of cancer resistance involves the production of a different form of high molecular weight hyaluronan, and much more of it, improving the anti-cancer mechanism of contact inhibition. In addition, other mechanisms derived from changes in hyaluronan may affect life span through improved cellular function, but this is less well explored. Researchers here take the naked mole-rat version of the gene for high molecular weight hyoluronan, hyaluronan synthase 2, and put it into mice. The result is less cancer, improved...
Source: Fight Aging! - August 31, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Biomaterial Injection Combines T Cell and Cancer Vaccine Treatments
Researchers at the Harvard Wyss Institute have developed an anti-cancer biomaterial treatment that combines adoptive T cell therapy and cancer vaccine technology to treat solid tumors. The researchers have called their technique SIVET, which is short...
Source: Medgadget - August 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Oncology harvard wyssinstitute Source Type: blogs
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Concept of Immune Resilience and Its Relevance to Degenerative Aging
The aging of the immune system is widely considered a progressive loss of functional capacity, such as the ability to effectively destroy pathogens and errant cells (known as immunosenescence), coupled to rising levels of unresolved, chronic inflammation (known as inflammaging). In today's open access paper, the authors are more interested in how well the immune system brings itself back to an equilibrium state following the disruptions of an inflammatory response. They call this capacity for restoration "immune resilience". In this framework, aging brings a loss of the ability to restore normality to the immune system fol...
Source: Fight Aging! - June 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Attacking Cancer by Disabling Macrophage Recognition of CD47 " Don ' t Eat Me " Marker
CD47 is a "don't eat me" decoration found on the surface of cells. This is a necessary mechanism for the prevention of autoimmunity, but it is also subverted by cancer in order to prevent the innate immune system from attacking tumor cells. The cancer research community has investigated a range of approaches to prevent CD47 from holding back the immune response to cancerous cells. One possibility, demonstrated here, is to engineer the innate immune cells known as macrophages in order to block the CD47 interaction and thus ensure an aggressive response to cancerous cells.
Cancer remains one of the leading causes of...
Source: Fight Aging! - June 20, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species.
We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Measures of Biological Age Largely Correlate with Cancer Risk
Cancer is an age-related condition. With age, there is a greater background of mutational damage that spreads throughout tissues. Greater inflammatory, pro-growth signaling by lingering senescent cells makes the environment more hospitable for cancerous growth once it is underway. The aging immune system becomes ever less able to destroy precancerous and cancerous cells rapidly enough to stop a cancer in its earliest stages.
Thus we should expect people who show an accelerated biological age to exhibit a greater risk of cancer, and this is largely the case. Most measures of biological age have quirks, however, as th...
Source: Fight Aging! - May 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Let Them Stay
Paul MatzkoDr. Muhil Ravichandran has a PharmD from Rutgers University and works in cancer research. She has lived legally in America for almost her entire life and is a model immigrant. Yet because of America’s broken immigration system, she’s going to beforced to leave her home and take her much ‐needed talents elsewhere.Ravichandran legally moved to the USA with her family when she was two years old, but when she became an adult she was no longer covered by her family ’s legal status. While in college she qualified for a student visa, but upon graduation she was forced to fall back on the vagaries of the ...
Source: Cato-at-liberty - May 2, 2023 Category: American Health Authors: Paul Matzko Source Type: blogs
The 2023 Skin-Checking Apps Landscape: Infographic
The most useful skin-checking applications allow users to take pictures of their suspicious skin lesions, upload these pictures to a server, the images are first evaluated by an AI algorithm and the results will be later validated by a dermatologist. We introduced several already, check here or here.
Earlier we called these apps an emerging trend, and still stand by this statement. If you are looking for a signature digital health solution, these are great examples, as they:
address an existing demand
rely on already existing infrastructure from the patients’ side (e.g.: their mobile phones)
provide ea...
Source: The Medical Futurist - March 20, 2023 Category: Information Technology Authors: Andrea Koncz Tags: Artificial Intelligence in Medicine Telemedicine & Smartphones future Healthcare technology skin checking digital health Source Type: blogs
Letting AI Physicians Into the Guild
BY KIM BELLARD
Let’s be honest: we’re going to have AI physicians.
Now, that prediction comes with a few caveats. It’s not going to be this year, and maybe not even in this decade. We may not call them “physicians,” but, rather, may think of them as a new category entirely. AI will almost certainly first follow its current path of become assistive technology, for human clinicians and even patients. We’re going to continue to struggle to fit them into existing regulatory boxes, like clinical decision support software or medical devices, until those boxes prove to be the wrong shape and size for ho...
Source: The Health Care Blog - March 14, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech AI physicians Kim Bellard Medical Education Prediction Source Type: blogs
Alpha TAU Killing Tumors With Highly Targeted Alpha Radiation
Radiation is commonly employed in hospitals around the world to treat tumors, typically using gamma ray beams of high energy photons, with a relatively long range, that penetrate all the tissues on the way to and from the tumor. This leads to substan...
Source: Medgadget - March 2, 2023 Category: Medical Devices Authors: Medgadget Editors Tags: Exclusive Oncology Radiation Oncology TelAvivUni Source Type: blogs
Terahertz Spectroscopy to Assess Severity of Skin Burns
Scientists at Stony Brook University in New York have developed a hand-held scanner that uses terahertz time-domain spectroscopy and neural network data analysis to non-invasively assess the severity of skin burns. At present, it is difficult to visu...
Source: Medgadget - February 9, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Dermatology Medicine Radiology Surgery stonybrooku Source Type: blogs
With access to my records, I took my business elsewhere
By EPATIENT DAVE DEBRONKART
Not our usual headshot but it is Dave!
I had a skin cancer diagnosed in November. It’s my third, and I researched the last one heavily, so I knew what I wanted (Mohs on the nose). But the hospital that did the diagnosis insisted I wait and have a consult visit in January, and *then* they’d let me schedule the procedure, probably in March.
I said I know what treatment I want – can’t I schedule the surgery now? They said, “That’s not how we do it.”
So I went home and called around. Beth Israel Deaconess Medical Center said if I could get th...
Source: The Health Care Blog - February 4, 2023 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care BIDMC ePatient Dave patient records TEFCA Source Type: blogs
