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History of cardiology : A soulful story of “ Dr.Thomas ” and his BT shunt
History is rarely kind to the original heroes in the scientific world.The classical Blalock-Taussig shunt,(BT shunt) the term we heard for the first time in the early clinical years of MBBS .We know, it as a dramatic cure (Palliative  though)  for the commonest congenital cyanotic heart disease -Tetralogy of Fallot. Now, half a century later, came to know, there is a gripping  story of an oppressed black hero behind this famous cardiac surgery. This post is  all about the  fascinating life of  Vivien Thomas,  a humble carpenter’s son from Nashville. While he dreamed to become a doctor, circumstances and fate h...
Source: Dr.S.Venkatesan MD - September 17, 2020 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized baltimore john hopkins BT shunt dr blalock dr helen b taussig history of cardiology modified bt shunt something lord made vivien thomas Source Type: blogs

Benefits On How 24 Hour Fasts Will Improve Your
Conclusion I showed you the benefits of fasting as it can improve your heart, protect your brain health, and reduce your body fat composition. I showed you how to safely start and make 24-hour fasts part of your lifestyle, and I also showed you the safest way to break a 24 hour fast. Let me know in the comments below which tip you found most useful! Anthony Nebel is a freelance writer who is obsessed with self-development. Anthony loves trying out new things that may improve his life. Anthony enjoys writing about how to improve the quality of your life and your online presence on his blog. The post Benefits ...
Source: PickTheBrain | Motivation and Self Improvement - September 14, 2020 Category: Consumer Health News Authors: Anthony Nebel Tags: featured health and fitness motivation fasting Source Type: blogs

Fight Aging! Newsletter, September 14th 2020
This study is the first to provide a direct link between this inflammation and plaque development - by way of IFITM3. Scientists know that the production of IFITM3 starts in response to activation of the immune system by invading viruses and bacteria. These observations, combined with the new findings that IFITM3 directly contributes to plaque formation, suggest that viral and bacterial infections could increase the risk of Alzheimer's disease development. Indeed, researchers found that the level of IFITM3 in human brain samples correlated with levels of certain viral infections as well as with gamma-secretase activ...
Source: Fight Aging! - September 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Meta-Analysis of the Ability of Exercise to Reduce Age-Related Mortality
The objective of this study was to conduct a systematic review and dose-response meta-analysis of physical activity and mortality in people with selected non-communicable diseases (NCDs). We aimed to define the dose-response relationship between post-diagnosis physical activity and mortality rates for nine NCDs with a high global burden of disease, including low back pain, type 2 diabetes (T2D), osteoarthritis, depressive disorder, chronic obstructive pulmonary disease (COPD), breast cancer, lung cancer, stroke, and ischemic heart disease (IHD). In total, 28 studies were included in the meta-analysis: 12 for breast ...
Source: Fight Aging! - September 10, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 7th 2020
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 6, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Federal Aid Creates Central ‐​Planning Power
This study argues that Congress should repeal all federal aid-to-state programs for many reasons, including that aid comes with costly strings attached that destroy local democracy.Richard Epstein and Mario Loyolanoted about aid programs: “When Americans vote in state and local elections, they think they are voting on state and local policies. But often they are just deciding which local officials get to implement the dictates of distant and insulated federal bureaucrats, whom even Congress can’t control.”I came across a table (p. 82) in New Jersey ’s budget that lists the $15 billion the state received in 2020 fro...
Source: Cato-at-liberty - September 4, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs

Assessing the Utility of Six of the Better Known Epigenetic Clocks in a Large Study Population
In conclusion, using a large cohort with rich health and DNA methylation data, we provide the first comparison of six major epigenetic measures of biological ageing with respect to their associations with leading causes of mortality and disease burden. DNAm GrimAge outperformed the other measures in its associations with disease data and associated clinical traits. This may suggest that predicting mortality, rather than age or homeostatic characteristics, may be more informative for common disease prediction. Thus, proteomic-based methods (as utilised by DNAm GrimAge) using large, physiologically diverse protein sets for p...
Source: Fight Aging! - September 4, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Why Primary Care Should Run the Healthcare System
By KEN TERRY (This is the fourth in a series of excerpts from Terry’s new book, Physician-Led Healthcare Reform: a New Approach to Medicare for All, published by the American Association for Physician Leadership.) Many other countries’ healthcare systems outperform ours for one simple reason: They place a much greater emphasis on primary care, which occupies the central place in their systems. “The evidence is that where you have more primary care physicians, where you coordinate care, and where you pay to keep people healthy, you get better outcomes at lower cost,” says David Nash, MD, founding dean of t...
Source: The Health Care Blog - September 4, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Primary Care Healthcare healthcare reform Ken Terry Source Type: blogs

How the Pandemic Is Taking Its Toll on Our Mental Health
The year 2020 will go down in history as one of the most devastating in history. Hundreds of thousands have died and millions have been hospitalized due to the novel coronavirus pandemic. COVID-19 has changed the lives of so many. No matter where you live, dealing with the effects of economic and physical lockdowns in a community leads to multiple mental health challenges. After months of living with the coronavirus, many people are getting tired, burned out, and more and more frustrated. In America, we face a particular challenge. Our federal government has chosen to take a backseat during the pandemic. Instead of leadin...
Source: World of Psychology - August 17, 2020 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: General Mental Health and Wellness Psychology Research coronavirus COVID-19 pandemic Source Type: blogs

Fight Aging! Newsletter, August 17th 2020
In this study, we sought to elucidate the role of VRK-1 in regulation of adult life span in C. elegans. We found that overexpression of VRK-1::GFP (green fluorescent protein), which was detected in the nuclei of cells in multiple somatic tissues, including the intestine, increased life span. Conversely, genetic inhibition of vrk-1 decreased life span. We further showed that vrk-1 was essential for the increased life span of mitochondrial respiratory mutants. We demonstrated that VRK-1 was responsible for increasing the level of active and phosphorylated form of AMPK, thus promoting longevity. A Fisetin Variant, C...
Source: Fight Aging! - August 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing Associations Between Physical Activity and Loss of Average Telomere Length with Age
Telomeres are repeated DNA sequences at the ends of chromosomes. With each cell division a little telomere length is lost, and this is an important part of the countdown mechanism that limits replication of somatic cells. Somatic cells with short telomeres become senescent or self-destruct. Stem cells, on the other hand, use telomerase to lengthen their telomeres, and thus produce daughter somatic cells with long telomeres throughout a lifetime. This two-tier system of privileged stem cells and limited somatic cells, present in near all animals, keeps the risk of cancer low enough for evolutionary success, while still allo...
Source: Fight Aging! - August 13, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

2 Supplements That Prevent Heart Disease And Cancer
The most recent trial confirms that two nutrients can reduce deaths from heart attacks and cancer. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - August 1, 2020 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Heart Disease Source Type: blogs

Podcast: Your Gut Instinct is Bad For Your Relationships
While caring for his wife as she struggled with a severe nervous breakdown, Dr. Gleb Tsipursky put the cognitive strategies he’d long been teaching others to work on his strained relationship. After seeing the incredible impact it had on his marriage as a whole, he decided to write a book to share these relationship-changing communication strategies. Join us as Dr. Tsipursky explains why going with your “gut” can actually backfire and shares 12 practical mental habits you can begin using today for excellent communication. We want to hear from you — Please fill out our listener survey by clicking the graphic a...
Source: World of Psychology - July 30, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Communication General Habits Interview LifeHelper Marriage and Divorce Podcast Relationships The Psych Central Show Source Type: blogs

Tackling obesity: empowering adults and children to live healthier lives
Department of Health and Social Care - It has been known for decades that living with obesity reduces life expectancy and increases the chance of serious diseases such as cancer, heart disease and type 2 diabetes. In the last few months it has been seen that excess weight puts individuals at risk of worse outcomes from coronavirus (Covid-19). This policy paper outlines actions the government will take to tackle obesity and help adults and children to live healthier lives.Policy paperPress release 
Source: Health Management Specialist Library - July 26, 2020 Category: UK Health Authors: The King ' s Fund Library Tags: Local authorities, public health and health inequalities Source Type: blogs

Fight Aging! Newsletter, July 27th 2020
In this study, we applied a well studied prediction model developed on data from five CpG sites, to increase the practicability of these tests. We have determined the biological age of the heart, specifically of the right atrium (RA) and left atrium (LA), and of peripheral blood leucocytes, by measuring the mitotic telomere length (TL) and the non-mitotic epigenetic age (DNAmAge). We found that DNAmAge, of both atrial tissues (RA and LA), was younger in respect to the chronological age (-12 years). Furthermore, no significant difference existed between RA and LA, suggesting that, although anatomically diverse and ex...
Source: Fight Aging! - July 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs