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Fight Aging! Newsletter, July 10th 2023
In conclusion, the examination of the GBA can aid in understanding the etiology and development of NDs, which may benefit the improvement of clinical treatments for these disorders and ND interventions. This review indicates existing knowledge about the involvement of microbiota present in the gut in NDs and potential treatment options. The Aging of the Enteric Nervous System https://www.fightaging.org/archives/2023/07/the-aging-of-the-enteric-nervous-system/ The enteric nervous system is the nervous system of the intestines, and likely an important part of the relationship between the gut microbiome a...
Source: Fight Aging! - July 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Progress Towards Rejuvenation as a Matter of Investment versus a Matter of Time
It is not hard to argue that there is too little investment in progress towards the treatment of aging as a medical condition. Collectively, the underlying mechanisms of degenerative aging are the cause of two-thirds of human mortality, and likely a somewhat greater fraction of loss of function, suffering, and pain. The cost of that mortality is vast, no matter how one likes to model the value of a human life, or a year spent alive in good health. This is much the same argument that can be made for greater investment in medical research in general. Medical research funding as a whole is a very, very tiny fraction of the co...
Source: Fight Aging! - July 4, 2023 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models. The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Against Prioritizing Environmentalism Over Human Health
It is fair to say that the mainstream of environmentalism prioritizes conservation of the environment over human comfort and health. Environmental concerns are high on the list of objections raised against treating aging as a medical condition, because most people believe that this will lead to a larger population, and also believe that population increases cannot occur without degrading the environment. Both of those beliefs are false, the latter evidently so given the improvements in the environment created since the 1950s, over a period of considerable population growth. Models strongly suggest that the future is one in...
Source: Fight Aging! - June 12, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Evidence-based hope in diabetes
In this study, the people with type 2 diabetes who didn’t have any of those extra risk factors, they’re likely to have had their first heart attack was less than people who didn’t have diabetes.So again, it’s only one study. I don’t want to overstate it, but the purpose of this is to say this is what’s possible. With good care, decent care, odds are pretty good, you can do well. And again, live a long and healthy life. So, evidence-based hope. Guys, what do you think?  Scott K. Johnson: I mean, that looks wonderfu...
Source: Scott's Diabetes Blog - June 1, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Clinical Examination of Cardiovascular System For Medical Students
Discussion on blood pressure is not included here as a separate topic is dedicated to it. Though the most commonly examined pulse is the radial, to check some of the characteristics, a more proximal pulse like the brachial or carotid needs to be examined. Following parameters of the pulse are routinely documented: 1. The rate: Normal rate in adult is 60-100 per minute. It is higher in children. Younger the child, higher the pulse rate. Rhythm: Regular and irregular rhythms are possible. Mild variation with respiration is called respiratory sinus arrhythmia, with higher rate in inspiration. Respiratory sinus arrhythmia may...
Source: Cardiophile MD - May 30, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect How to Construct Measures of Biological Age A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome Intestinal Barrier Dysfunction as a Feature of Aging in Many Species NAFLD as an Age-Related Condition Towards Sensory Hair Cell Regeneration in the Inner Ear Raised Levels of PLG...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 15th 2023
In this study, we examined the average telomere length and telomerase activity, as well as the formation of telomere associated foci (TAFs) and the mRNA expression levels of the shelterin components in cultured primary cells of Spalax, a long-lived, hypoxia-tolerant, and cancer-resistant blind mole-rat species. We showed that with cell passages, Spalax fibroblasts demonstrated significant shortening in telomere length, similar to rat cells, and in line with the processes observed earlier in tissues. We also demonstrated that the average telomere length in Spalax fibroblasts was significantly higher than the average ...
Source: Fight Aging! - May 14, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Athletes Exhibit Half the Incidence of Hypertension in the General Population
Cardiovascular aging is greatly influenced by exercise and physical fitness, to the point at which one can point to physically active hunter-gatherer populations that exhibit very few of the common cardiovascular issues present in wealthier first world populations. Researchers here report on a study of cardiovascular aging in competitive athletic individuals, noting that they exhibit less than half of the risk of hypertension observed in the general population. This is one of many examples of the way in which athletes tend to be healthier than the average. Master athlete is a term applied to individuals typically ...
Source: Fight Aging! - May 8, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features – April 30, 2023 – 68% of providers say improving patient collections is a high priority, hospital expenses have increased 2x the Medicare IPPS reimbursement rate since 2019, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies Compared to other industries, healthcare is leading the way in improving networks to support edge computing, according to the latest AT&T Cybersecurity Insights Report. Budgets for edge computing go into fo...
Source: EMR and HIPAA - April 30, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AHA AltaMed AT&T AvaSure Butterfly Network Censinet Clearwater Clinician Nexus Conifer Health Solutions CWH Advisors Cyturus Datavant DrFirst eClinicalWorks eCW Fortified Health Security Healthcare IT Today Source Type: blogs

Nutrition: Major Government Fail?
Chris EdwardsAmericans are getting used to failures by government experts. Government economists have a  dismal forecasting record. Government actions and advice during the pandemic were often misguided. And dozens of former government intelligence experts got the Hunter Biden laptop storywrong.A less recognized but also important failure may be in nutrition. Federal experts appear to have issued faulty advice for decades, even as American obesityexploded from 15 percent in the 1970s to 42 percent today. Federal guidance on nutrition has a  large influence on health practice across society. Some researchers argue that Am...
Source: Cato-at-liberty - April 26, 2023 Category: American Health Authors: Chris Edwards Source Type: blogs

Obesity is crippling the US, but there are solutions
By STEPHANIE TILENIUS Well over a third of Americans are obese — and the percentage keeps growing at a staggering rate. Over the last twenty years, obesity prevalence grew from 30% to 42% of the US population and rates of severe obesity nearly doubled. If we don’t make serious changes to our healthcare system, it’s scary to think where we’re headed in a few short years. The fact is, obesity is far from a cosmetic condition. It can be a devastating disease and was classified as such by the American Medical Association in 2013. Obesity is the leading risk factor for deadly diseases like type 2 diabetes, heart d...
Source: The Health Care Blog - April 13, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy GLP-1 Obesity Stephanie Tilenius vida health Source Type: blogs

Farm Bill 2023 and Obesity
This study found U.S. farm policies “have generally small and mixed effects on farm commodity prices, which in turn have even smaller and still mixed effects on the relative prices of more‐ and less‐​fattening foods.”Farm subsidy/ ​nutrition issues are hotly debated, and I have not done a detailed research review. If Congress withdrew subsidies from corn, wheat, soybeans, and rice, would U.S. farming shift toward healthier fruits and vegetables? Are the subsidized crops and related oils a cause of obesity, and has the go vernment given Americans bad nutrition advice about these products for decades, asNina T...
Source: Cato-at-liberty - April 6, 2023 Category: American Health Authors: Chris Edwards Source Type: blogs