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Fight Aging! Newsletter, July 27th 2020
In this study, we applied a well studied prediction model developed on data from five CpG sites, to increase the practicability of these tests. We have determined the biological age of the heart, specifically of the right atrium (RA) and left atrium (LA), and of peripheral blood leucocytes, by measuring the mitotic telomere length (TL) and the non-mitotic epigenetic age (DNAmAge). We found that DNAmAge, of both atrial tissues (RA and LA), was younger in respect to the chronological age (-12 years). Furthermore, no significant difference existed between RA and LA, suggesting that, although anatomically diverse and ex...
Source: Fight Aging! - July 26, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Does air pollution cause Alzheimer ’s disease?
Have you ever spent the day in a city with such bad air pollution that when you blew your nose the mucus had a black tinge? Have you ever coughed as you breathed in diesel fumes from a passing bus and thought to yourself, “Well, that’s a year gone from my life”? Could it actually be true — that air pollution leads to an early death? The answer, in fact, is an unqualified yes. Air pollution causes heart disease, lung disease, and early death It has been known for some time that air pollution causes lung cancer, chronic obstructive pulmonary disease, emphysema, asthma, heart disease, and stroke. One recent study in C...
Source: Harvard Health Blog - July 23, 2020 Category: Consumer Health News Authors: Andrew E. Budson, MD Tags: Alzheimer's Disease Environmental health Healthy Aging Memory Neurological conditions Source Type: blogs

Fight Aging! Newsletter, July 13th 2020
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
Source: Fight Aging! - July 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lifestyle Medicine Could Be The Key For Digital Health Adoption
I’ve been wearing my Fitbit for a couple of years and only remove it when I shower. I use it to track my sleep and its smart alarm wakes me up at the optimal time every morning. With the pocketable Kardia, I regularly check my ECG at home to detect any anomalies. For an in-depth analysis of what my genetic makeup predisposes me to, I had my whole genome sequenced. And I bring relevant data to my general practitioner during my checkups so that we can decide on preventive measures. In short, I’m trying to live like the patient of the future. However, posing as such a patient is not feasible for many among us. Firs...
Source: The Medical Futurist - June 23, 2020 Category: Information Technology Authors: Prans Tags: Lifestyle medicine E-Patients Health Sensors & Trackers Healthcare Design Medical Education Personalized Medicine sleep stress food scanner sleep apnea Apple Watch Dr. Vernes Baylor ACLM Source Type: blogs

Fight Aging! Newsletter, June 15th 2020
In this study, we used markers to monitor the formation of SGs in Caenorhabditis elegans. We found that, in addition to acute heat stress, SG formation could also be triggered by dietary changes, such as starvation and dietary restriction (DR). We found that HSF-1 is required for the SG formation in response to acute heat shock and starvation but not DR, whereas the AMPK-eEF2K signaling is required for starvation and DR-induced SG formation but not heat shock. Moreover, our data suggest that this AMPK-eEF2K pathway-mediated SG formation is required for lifespan extension by DR, but dispensable for the longevity by reduced ...
Source: Fight Aging! - June 14, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 1st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 31, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What ’s a diagnosis about? COVID-19 and beyond
By MICHEL ACCAD Last month marked the 400th anniversary of the birth of John Graunt, commonly regarded as the father of epidemiology.  His major published work, Natural and Political Observations Made upon the Bills of Mortality, called attention to the death statistics published weekly in London beginning in the late 16th century.  Graunt was skeptical of how causes of death were ascribed, especially in times of plagues.  Evidently, 400 years of scientific advances have done little to lessen his doubts!  A few days ago, Fox News reported that Colorado governor Jared Polis had “pushed back against recen...
Source: The Health Care Blog - May 28, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Physicians Diagnosis MICHEL ACCAD Source Type: blogs

AI-Powered Teleradiology FDA Cleared for Triage in Departments Swamped by COVID-19: Interview with David Stavens, CEO of Nines
Nines, a teleradiology company based in Palo Alto, CA, recently received FDA clearance for their NinesAI medical device, which supports the automated radiological review of CT Head images for the possible presence of two time-critical, life-threateni...
Source: Medgadget - May 21, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Radiology Telemedicine Source Type: blogs

Network Medicine in the Fight Against COVID-19
COVID-19 forced stakeholders in the healthcare landscape to adopt a new perspective in this sphere. Telemedicine rose to fame as a ready-made solution; artificial intelligence’s contribution became more apparent from early outbreak predictions to resource management; and digital health technologies lent a helping hand early on. Another promising area joining the fight is network medicine, a branch of network science. The latter field studies the interaction between actors within a network. Such analyses are applicable to virtually any sector, from the world wide web through social networks to how molecules interact wi...
Source: The Medical Futurist - May 21, 2020 Category: Information Technology Authors: Prans Tags: Network medicine Artificial Intelligence Biotechnology Telemedicine & Smartphones AI MIT coronavirus covid covid19 vaccine research pandemic network science Albert-László Barabási Source Type: blogs

Some healthcare can safely wait (and some can ’t)
Among the many remarkable things that have happened since the COVID-19 pandemic began is that a lot of our usual medical care has simply stopped. According to a recent study, routine testing for cervical cancer, cholesterol, and blood sugar is down nearly 70% across the country. Elective surgeries, routine physical examinations, and other screening tests have been canceled or rescheduled so that people can stay at home, avoid being around others who might be sick, and avoid unknowingly spreading the virus. Many clinics, hospitals, and doctors’ offices have been closed for weeks except for emergencies. Even if these facil...
Source: Harvard Health Blog - May 20, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Health care Healthy Aging Men's Health Women's Health Source Type: blogs

Fight Aging! Newsletter, May 18th 2020
This study provides direct evidence for the contribution of gut microbiota to the cognitive decline during normal aging and suggests that restoring microbiota homeostasis in the elderly may improve cognitive function. On Nutraceutical Senolytics https://www.fightaging.org/archives/2020/05/on-nutraceutical-senolytics/ Nutraceuticals are compounds derived from foods, usually plants. In principle one can find useful therapies in the natural world, taking the approach of identifying interesting molecules and refining them to a greater potency than naturally occurs in order to produce a usefully large therape...
Source: Fight Aging! - May 17, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

And now for some good news on health
When it comes to health concerns, the COVID-19 pandemic is top of mind for most people right now. And that’s for good reason. But there is some very good non-COVID health news that may not be getting the attention it deserves. According to the CDC, the rates of six of the top 10 causes of death in this country, which account for about three-quarters of all deaths, have been declining. That’s remarkable. And these improvements are occurring despite an aging population and an obesity epidemic that affects several health conditions. Six positive health trends Let’s look at the trends in these conditions and their rank ...
Source: Harvard Health Blog - May 15, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Cancer Health Health trends Heart Health Source Type: blogs

Physical Activity Slows the Consequences of Aging
We live in a world in which most people do not undertake anywhere near the level of physical activity that is optimal. Thus adding greater physical activity as a lifestyle choice appears very beneficial. There is a great deficiency, one that has serious consequences to health, and fixing that deficiency is touted as a successful intervention. But in reality, the situation is one in which most people harm their long term health through a form of self-neglect. This era of cheap calories and comfort is a time of vast benefits for humanity - but it has a few downsides, and this is one of them. This meta-analysis showe...
Source: Fight Aging! - May 12, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Our Suffering Parents' Deaths Can Bring Both Sorrow and Relief
Photo credit Neonbrand Dear Carol: Both of my parents were ill for years. Mom, who died two years ago, fought several types of cancer and then developed dementia. Dad, who died three months ago, had a massive stroke right after Mom’s death and his last years were full of physical and emotional pain. My brother and I grieve our parents, but we saw them wear out from health struggles and feel that they are now together in a better place, so there’s quite of bit of relief, as well. Knowing our parents are no longer suffering is part of the relief, but I’m also relieved that I can now spend more time with my husband and ...
Source: Minding Our Elders - April 30, 2020 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Weight loss can help head off lasting damage caused by fatty liver
Non-alcoholic fatty liver disease is the most common cause of liver disease in the United States, and is estimated to affect up to a quarter of adults in the world. It is defined by excess fat accumulating in the liver and usually occurs in people with obesity, high blood sugars (diabetes), abnormal cholesterol or triglyceride levels, or high blood pressure. These disorders often run together and as a group are called metabolic syndrome. The “non-alcoholic” part of “non-alcoholic fatty liver disease” is important to distinguish it from alcohol-related liver disease, which can also cause excess liver fat. How fat ca...
Source: Harvard Health Blog - April 30, 2020 Category: Consumer Health News Authors: Irun Bhan, MD Tags: Diet and Weight Loss Digestive Disorders Source Type: blogs