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Announcing GuideWell ’s Caring for Caregivers Challenge
SPONSORED POST By CATALYST @ HEALTH 2.0 Caregivers who care for aging, ill and disabled adult family members face a broad array of challenges within their daily lives. These challenges include stress, burnout, financial burdens, career sacrifices, sleep deprivation, depression, isolation, and lack of privacy. GuideWell believes it “takes a village” to sustainably support family caregivers, and that single point solutions are typically not broad enough to provide comprehensive relief to family caregivers. GuideWell, in collaboration with Catalyst @ Health 2.0, is excited to announce the Caring for Caregive...
Source: The Health Care Blog - September 23, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Catalyst @ Health 2.0 Health Tech Health Technology Start-Ups Caring for Caregivers GuideWell home based care Source Type: blogs

Fight Aging! Newsletter, September 23rd 2019
Discussion of Developmental Effects on Aging Microtubule Function and Longevity in Nematodes Quantifying the Correlation Between Poverty and Faster Pace of Aging Matthew O'Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019 https://www.fightaging.org/archives/2019/09/matthew-oconnor-presenting-on-underdog-pharmaceuticals-at-undoing-aging-2019/ Here Matthew O'Connor of the SENS Research Foundation talks about the research that led to founding of Underdog Pharmaceuticals, a biotech startup incubated by the foundation to commercialize a means of targeting 7-ketocholesterol in atheroscleros...
Source: Fight Aging! - September 22, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Harvard Health Ad Watch: What you should know about direct-to-consumer ads
If you’re like most people, you’ve seen a ton of direct-to-consumer (DTC) drug ads in recent years. They’re all over television, in magazines, online, on billboards, and slapped on the sides of buses, promoting treatments for arthritis, cancer, heartburn, psoriasis, flagging memory — and more. The deluge of drug ads can be overwhelming. Worse, the information is often incomplete, biased, or confusing. That’s why we’re launching the Harvard Health Ad Watch series to highlight some benefits and problems with health product advertisements. We’ll focus on the evidence behind the ads and show you how — a...
Source: Harvard Health Blog - September 20, 2019 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Children's Health Drugs and Supplements Men's Health Women's Health Source Type: blogs

Fight Aging! Newsletter, September 16th 2019
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - September 15, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 9th 2019
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - September 8, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Narcissistic Parents Pose Special Challenge to Adult Children
Photo credit Mosoianu Bogdan Dear Carol: I grew up with a mentally ill, completely self-absorbed mother and absent father. With the help of therapists over the years, I’ve survived and even done well, but childhood pain never leaves us. Now, my mother, who has been diagnosed as narcissistic, is reaching the age where her physical health and her ability to make decisions are both declining. She’s had a number of mini-strokes and extremely high blood pressure. I’ve done all of the recommended things I can do to convince her to get Powers of Attorney assigned, if not to me, her only child then to an attorney, but she wo...
Source: Minding Our Elders - September 7, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

TAME Trial for the Effects of Metformin in Humans to Proceed this Year
Researchers and advocates have been trying for some years to launch the TAME trial to assess the effects of metformin on aging in humans. This is not with the hope of producing meaningful effects on the progression of aging. Metformin has a small effect size, being one of the less effective interventions that upregulates cellular stress responses, a strategy that in and of itself is weak in long-lived species such as our own. The goal is to push the FDA into accepting clinical trials that target mechanisms of aging rather than a specific named age-related condition. Metformin was chosen because its safety profile, widespre...
Source: Fight Aging! - September 6, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, September 2nd 2019
In conclusion, in the absence of obesity, visceral adipose tissue possesses a pronounced anti-inflammatory phenotype during aging which is further enhanced by exercise. Methods of Inducing Cellular Damage are Rarely Relevant to Aging, and the Details Matter https://www.fightaging.org/archives/2019/08/methods-of-inducing-cellular-damage-are-rarely-relevant-to-aging-and-the-details-matter/ One of the major challenges in aging research is determining whether or not models of cellular or organismal damage and its consequences are in any way relevant to the natural processes of aging. One can hit a brick with...
Source: Fight Aging! - September 1, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 26th 2019
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - August 25, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 19th 2019
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - August 18, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Everyone Is Having the Wrong Healthcare Debate
By STEVEN MERAHN, MD In 1807, in an effort to spite the British and French for shipping interference (and forced recruitment of American citizens into military service), the United States Congress passed an Embargo Act, effectively shutting down trade with these two countries. Britain and France quickly found other trading partners; the US, then limited in our capacity to sell products outside our borders, was left with a devastated economy and a gaping hole in our face. It took only weeks before Congress passed a loophole; they repealed the act within 15 months of its passing. It was a great lesson in unintended co...
Source: The Health Care Blog - August 16, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Politics Uncategorized Health care debate Health Care Reform Steven Merahn universal healthcare Source Type: blogs

Fight Aging! Newsletter, August 12th 2019
We examined 9293 individuals from the Copenhagen General Population Study using nuclear magnetic resonance spectroscopy measurements of total cholesterol, free- and esterified cholesterol, triglycerides, phospholipids, and particle concentration. Fourteen subclasses of decreasing size and their lipid constituents were analysed: six subclasses were very low-density lipoprotein (VLDL), one intermediate-density lipoprotein (IDL), three low-density lipoprotein (LDL), and four subclasses were high-density lipoprotein (HDL). Remnant lipoproteins were VLDL and IDL combined. Mean nonfasting cholesterol concentration was 72...
Source: Fight Aging! - August 11, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Do You Tell Someone With Dementia When a Loved One Has Died?
Photo credit Christian Newman ...My friend can be forgiven for dragging her feet. Her mother has been told often that the brother was ill. It was new information to the mother each time. There was no reason for the daughter to think that the telling of her uncle's death was not going to shock her mother all over again. She seriously thought of not mentioning it. It's not as if a visit was expected. She asked me what I thought. Read the full article on HealthCentral to learn more about how (or if) to tell someone that their spouse or other loved one has died: Carol Bradley Bursack is the Candid Caregiver MedicareFAQ – Med...
Source: Minding Our Elders - August 7, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

How We Approach Caring for Aging Parents Who Didn ’t Care for You
Photo credit Richard Jaimes ...As we talked, Nancy described the inner turmoil she was facing as her parents got older. She grew up with a physically and emotionally abusive mother, and her father was gone much of the time, doing what most men of that generation did: making a living to support his family. Therefore, he wasn’t around to “interfere” with the raising of the children. Nancy had spent years in therapy learning to cope with her childhood issues.  Read the full article on Agingcare to learn more about how to approach caring for parents who never cared for you: Carol Bradley Bursack is the Candid Careg...
Source: Minding Our Elders - August 6, 2019 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

A Proposal to Improve Healthcare and Make It More Affordable
By STEVE ZECOLA Americans spend about $3 trillion per year on healthcare, or about $10,000 per person per year. Despite these expenditures, Americans are worse off than their international counterparts with respect to infant mortality, life expectancy and the prevalence of chronic conditions. In policy debates, Republicans mostly prefer to let the marketplace devise the appropriate outcomes, but this approach ignores the market failures that plague the industry. On the other hand, Democrats propose a variety of solutions such as “Medicare for All” which nationalizes all healthcare insurance or, as a variant, ...
Source: The Health Care Blog - August 6, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Medicare For All Source Type: blogs