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Total 21938 results found since Jan 2013.
Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
CONCLUSION: This study serves as a comprehensive update of the epidemiology of brain and spinal tumours and could help guide further studies on brain and spinal tumours.PMID:37675681 | DOI:10.4103/singaporemedj.SMJ-2022-069
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Mervyn Jun Rui Lim Yilong Zheng Sean Wai-Onn Eng Celest Wen Ting Seah Shuning Fu Lucas Zheng Long Lam Joel Yat Seng Wong Balamurugan Vellayappan Andrea Li-Ann Wong Kejia Teo Vincent Diong Weng Nga Sein Lwin Tseng Tsai Yeo Source Type: research
Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
CONCLUSION: This study serves as a comprehensive update of the epidemiology of brain and spinal tumours and could help guide further studies on brain and spinal tumours.PMID:37675681 | DOI:10.4103/singaporemedj.SMJ-2022-069
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Mervyn Jun Rui Lim Yilong Zheng Sean Wai-Onn Eng Celest Wen Ting Seah Shuning Fu Lucas Zheng Long Lam Joel Yat Seng Wong Balamurugan Vellayappan Andrea Li-Ann Wong Kejia Teo Vincent Diong Weng Nga Sein Lwin Tseng Tsai Yeo Source Type: research
Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
CONCLUSION: This study serves as a comprehensive update of the epidemiology of brain and spinal tumours and could help guide further studies on brain and spinal tumours.PMID:37675681 | DOI:10.4103/singaporemedj.SMJ-2022-069
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Mervyn Jun Rui Lim Yilong Zheng Sean Wai-Onn Eng Celest Wen Ting Seah Shuning Fu Lucas Zheng Long Lam Joel Yat Seng Wong Balamurugan Vellayappan Andrea Li-Ann Wong Kejia Teo Vincent Diong Weng Nga Sein Lwin Tseng Tsai Yeo Source Type: research
Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
CONCLUSION: This study serves as a comprehensive update of the epidemiology of brain and spinal tumours and could help guide further studies on brain and spinal tumours.PMID:37675681 | DOI:10.4103/singaporemedj.SMJ-2022-069
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Mervyn Jun Rui Lim Yilong Zheng Sean Wai-Onn Eng Celest Wen Ting Seah Shuning Fu Lucas Zheng Long Lam Joel Yat Seng Wong Balamurugan Vellayappan Andrea Li-Ann Wong Kejia Teo Vincent Diong Weng Nga Sein Lwin Tseng Tsai Yeo Source Type: research
Suprasellar masquerader: Chordoid glioma
CONCLUSION: The rare occurrence as well as the radiological and morphological overlaps in chordoid gliomas make them a true masquerader. Combination of GFAP and TTF-1 in the immunohistochemical panel can be useful in differential diagnosis. Mainstay of treatment is complete surgical excision, with adjuvant radiotherapy becoming increasingly important.PMID:37675487 | DOI:10.5414/NP301577
Source: Clinical Neuropathology - September 7, 2023 Category: Pathology Authors: Neha Bhardwaj Pravin Salunke Navneet Singla Chirag Ahuja Chandrashekhar Gendle Kirti Gupta Source Type: research
Presenting characteristics, histological subtypes and outcomes of adult central nervous system tumours: retrospective review of a surgical cohort
CONCLUSION: This study serves as a comprehensive update of the epidemiology of brain and spinal tumours and could help guide further studies on brain and spinal tumours.PMID:37675681 | DOI:10.4103/singaporemedj.SMJ-2022-069
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Mervyn Jun Rui Lim Yilong Zheng Sean Wai-Onn Eng Celest Wen Ting Seah Shuning Fu Lucas Zheng Long Lam Joel Yat Seng Wong Balamurugan Vellayappan Andrea Li-Ann Wong Kejia Teo Vincent Diong Weng Nga Sein Lwin Tseng Tsai Yeo Source Type: research
Cancers, Vol. 15, Pages 4453: Non-Invasive Assessment of Isocitrate Dehydrogenase-Mutant Gliomas Using Optimized Proton Magnetic Resonance Spectroscopy on a Routine Clinical 3-Tesla MRI
Conclusions: Noninvasive optimized 1H-MRS may be useful in predicting IDH mutational status and 2HG may serve as a valuable diagnostic and prognostic biomarker in patients with gliomas
Source: Cancers - September 7, 2023 Category: Cancer & Oncology Authors: Laiz Laura de Godoy Kheng Choon Lim Archith Rajan Gaurav Verma Mauro Hanaoka Donald M. O ’Rourke John Y. K. Lee Arati Desai Sanjeev Chawla Suyash Mohan Tags: Article Source Type: research
Immunotherapy: a promising approach for glioma treatment
Gliomas are the most prevalent primary malignant brain tumors worldwide, with glioblastoma (GBM) being the most common and aggressive type. Despite two decades of relentless pursuit in exploring novel therapeutic approaches for GBM, there is limited progress in improving patients’ survival outcomes. Numerous obstacles impede the effective treatment of GBM, including the immunosuppressive tumor microenvironment (TME), the blood-brain barrier, and extensive heterogeneity. Despite these challenges, immunotherapies are emerging as a promising avenue that may offer new hope for the treatment of gliomas. There are four main ty...
Source: Frontiers in Immunology - September 7, 2023 Category: Allergy & Immunology Source Type: research
Clinical characterization and immunosuppressive regulation role of EFHD2 (swiprosin-1) in Glioma-associated macrophages
In conclusion, EFHD2 promises to be a key target for TME-related immunotherapy.PMID:37673235 | DOI:10.1016/j.ygeno.2023.110702
Source: Genomics - September 6, 2023 Category: Genetics & Stem Cells Authors: Wen-Zhao Zhang Lin-Lin Chen Shuo Yang Yu-Ting Zhong Xin Lu Yan Wang Zhi-Bin Wang Ye Tu Source Type: research
