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A network meta-analysis of different acupuncture modalities in the treatment of bronchial asthma
Glucocorticoids and Beta-2 receptor agonists are commonly used for the treatment of asthma in clinical practice, while these agents are accompanied by adverse reactions of different kinds. Studies have shown t...
Source: BMC Pulmonary Medicine - September 22, 2023 Category: Respiratory Medicine Authors: Xingyi Wang, Shuyun Zeng, Zhuying Li, Yue Li and Hongtao Jia Tags: Research Source Type: research

Secular trend of mortality and incidence of rheumatoid arthritis in global ,1990 –2019: an age period cohort analysis and joinpoint analysis
Rheumatoid arthritis (RA) is a major public health problem. Unfortunately, there is a scarcity of comprehensive and up-to-date information regarding the burden of RA and its dynamic trends in subsequent years....
Source: BMC Pulmonary Medicine - September 22, 2023 Category: Respiratory Medicine Authors: Fangyuan Yu, Hongwei Chen, Qi Li, Mengjun Tao, Ziyi Jin, Linyu Geng and Lingyun Sun Tags: Research Source Type: research

Prevalence, Clinical Profiles, and Prognosis of Stiff-Person Syndrome in a Japanese Nationwide Survey
This study provides the current epidemiologic and clinical status of SPS in Japan. The symptom onset to the diagnosis of SPS was longer in patients with high-titer GAD65 antibodies than in those with low-titer GAD65 antibodies. The outcome of patients with SPS was generally favorable, but more aggressive immunotherapies are necessary for GAD65-positive patients with SPS.
Source: Neurology Neuroimmunology and Neuroinflammation - September 22, 2023 Category: Neurology Authors: Matsui, N., Tanaka, K., Ishida, M., Yamamoto, Y., Matsubara, Y., Saika, R., Iizuka, T., Nakamura, K., Kuriyama, N., Matsui, M., Arisawa, K., Nakamura, Y., Kaji, R., Kuwabara, S., Izumi, Y., for the Japanese SPS Study Tags: Autoimmune diseases, Clinical neurology examination, Cohort studies, Prevalence studies Research Article Source Type: research

Overhead squat assessment reflects treadmill running kinematics
ConclusionsOHSA was associated with some important and dysfunction-related hip, knee and ankle kinematics. Running coaches, may use OHSA as an assessment tool before the corrective training plan to detect injury-related compensation patterns to reduce the risk of injury and improve running technique.
Source: BMC Sports Science, Medicine and Rehabilitation - September 22, 2023 Category: Sports Medicine Source Type: research

Effect of robotic-assisted gait training on gait and motor function in spinal cord injury: a protocol of a systematic review with meta-analysis
Introduction Robotic-assisted gait training (RAGT) has been reported to be effective in rehabilitating patients with spinal cord injury (SCI). However, studies on RAGT showed different results due to a varied number of samples. Thus, summarising studies based on robotic-related factors is critical for the accurate estimation of the effects of RAGT on SCI. This work aims to search for strong evidence showing that using RAGT is effective in treating SCI and analyse the deficiencies of current studies. Methods and analysis The following publication databases were electronically searched in December 2022 without restrictions ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Wang, L., Peng, J.-l., Chen, A.-l. Tags: Open access, Rehabilitation medicine Source Type: research

Daytime sleepiness in Chinese professional, semi professional and students soccer players in the Shanghai lockdown
ConclusionsThis study shows the first data on sleepiness in Chinese soccer players of different level of qualification immediately post lockdown condition. Professional male ’s players sleepiness was lower, than females, SS and SP after the exceptional lockdown measures. The reasons can reside in the more ordered lifestyle of PP in comparison to SS and SP, which mitigated the effects of the lockdown. Our results suggest that measures to improve sleep in females’ soc cer player should be adopted if these exceptional conditions will happen again.
Source: BMC Sports Science, Medicine and Rehabilitation - September 22, 2023 Category: Sports Medicine Source Type: research

Dietary supplements to reduce symptom severity and duration in people with SARS-CoV-2: a double-blind randomised controlled trial
Background COVID-19 has caused morbidity, hospitalisation and mortality worldwide. Despite effective vaccines, there is still a need for effective treatments, especially for people in the community. Dietary supplements have long been used to treat respiratory infections, and preliminary evidence indicates some may be effective in people with COVID-19. We sought to evaluate whether a combination of vitamin C, vitamin D3, vitamin K2 and zinc could improve overall health and decrease symptom burden in outpatients diagnosed with COVID-19. Methods Participants were randomised to receive either vitamin C (6 g), vitamin D3 (1000...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Seely, D., Legacy, M., Conte, E., Keates, C., Psihogios, A., Ramsay, T., Fergusson, D. A., Kanji, S., Simmons, J.-G., Wilson, K. Tags: Open access, Complementary medicine, COVID-19 Source Type: research

Association between using a prehospital assessment unit and hospital admission and mortality: a matched cohort study
Conclusion The recently introduced PAU aims for patient-centred emergency care. The PAU-assessed patients had reduced admissions within 48 hours and 7 days after the initial call. Study findings indicate that the PAU is safe since we identified no significant differences in 30-day mortality. Trial registration number NCT05654909.
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Wolthers, S. A., Blomberg, S. N. F., Breindahl, N., Anjum, S., Hägi-Pedersen, D., Ersboll, A., Andersen, L. B., Christensen, H. C. Tags: Open access, Emergency medicine Source Type: research

Parking behaviour under the influence of alcohol
In this study, 29 test persons (13 m, 16 f) completed three test drives with real cars, each made up of three different parking situations. While four test persons remained sober, the majority drank a previously calculated amount of alcohol before the second drive; the aim was to reach a blood alcohol concentration (BAC) of 1.1 g/kg. The third drive took place about 2 h later without any further ingestion of alcohol. The impact of BAC on the number of accidents, time needed to finish the drive, the amount of correction moves and quality of the final parking position (in the centre of the parking space) were analysed. Furth...
Source: International Journal of Legal Medicine - September 22, 2023 Category: Medical Law Source Type: research

Validation of the Efficacy of Ultrasound Speckle Tracking in Measuring Tendon Gliding After Finger Flexor Tendon Repair
Restricted tendon gliding is commonly observed in patients after finger flexor tendon (FFT) repair. The study described here was aimed at quantifying the amount of FFT gliding to evaluate the recovery of post-operative tendons using a 2-D radiofrequency (RF)-based ultrasound speckle tracking algorithm (UST).
Source: Ultrasound in Medicine and Biology - September 22, 2023 Category: Radiology Authors: Ming-Wei Wang, Wei-Ning Lee, Chih-Chien Hung, Jung-Hsien Hsieh, Yueh-Hsia Chen, Tiffany Ting-Fang Shih, Jyh-Horng Wang, Nai-Hao Yin, Hsing-Kuo Wang Tags: Original Contribution Source Type: research

Paradigm Lost: Towards an Evidence-based Ontology in Psychedelic Medicine?
AbstractRecent research into so-called psychedelic substances, such as psilocybin, ketamine, and mescaline analogues, has been hailed as a “renaissance” heralding a “paradigm shift” in psychiatry. There is hope that psychedelic-assisted therapy will be made more available to address mental and substance use health problems through existing systems of medicalization and legalization. There are important relational and epistemic concerns that must be addressed, however, before we might begin stewarding this class of substances into the medical landscape in a responsible, evidence-based manner. In this paper, we draw ...
Source: International Journal of Mental Health and Addiction - September 22, 2023 Category: Addiction Source Type: research

Psychological Safety for Mental Health in Elite Sport: A Theoretically Informed Model
AbstractElite sports contexts are highly pressurised and frequently enforce a win-at-all-costs approach. This narrow focus on performance outcomes can potentially contribute in negative ways to the mental health of those within these environments. In thisCurrent Opinion paper, we propose a model that outlines how key elements contributing to psychologically safe or unsafe environments may contribute to better or worse mental health outcomes, respectively. In an environment in which individuals feel safe to show their authentic selves rather than ‘wear a mask’, different experiences of mental health are likely to be nor...
Source: Sports Medicine - September 22, 2023 Category: Sports Medicine Source Type: research

The Additional Effect of Training Above the Maximal Metabolic Steady State on VO2peak, Wpeak and Time-Trial Performance in Endurance-Trained Athletes: A Systematic Review, Meta-analysis, and Reality Check
ConclusionA single training meso-cycle that includes training above MMSS can improveVO2peak in endurance-trained athletes more than training only below MMSS. However, we do not have sufficient evidence to conclude that concurrent adaptation occurs forWpeak or TT performance.
Source: Sports Medicine - September 22, 2023 Category: Sports Medicine Source Type: research

Does patient behaviour drive physicians to practice defensive medicine? Evidence from a video experiment
ConclusionsOur results show that patients ’ critical attitude drives physicians’ perceived liability risk and consequent defensive behaviour among obstetricians/gynaecologists and orthopaedists.
Source: Health Economics Review - September 22, 2023 Category: International Medicine & Public Health Source Type: research

Recommendations on data sharing in HIV drug resistance research
by Seth C. Inzaule, Mark J. Siedner, Susan J. Little, Santiago Avila-Rios, Alisen Ayitewala, Ronald J. Bosch, Vincent Calvez, Francesca Ceccherini-Silberstein, Charlotte Charpentier, Diane Descamps, Susan H. Eshleman, Joseph Fokam, Lisa M. Frenkel, Ravindra K. Gupta, John P.A. Ioannidis, Pontiano Kaleebu, Rami Kantor, Seble G. Kassaye, Sergei L. Kosakovsky Pond, Vinie Kouamou, Roger D. Kouyos, Daniel R. Kuritzkes, Richard Lessells, Anne-Genevieve Marcelin, Lawrence Mbuagbaw, Brian Minalga, Nicaise Ndembi, Richard A. Neher, Roger Paredes, Deenan Pillay, Elliot G. Raizes, Soo-Yon Rhee, Douglas D. Richman, Kiat Ruxrungtham, P...
Source: PLoS Medicine - September 22, 2023 Category: Internal Medicine Authors: Seth C. Inzaule Source Type: research