Filtered By:
Cancer: Adenocarcinoma
This page shows you your search results in order of date. This is page number 6.
Order by Relevance | Date
Total 24759 results found since Jan 2013.
Cancer cell-intrinsic PD-1: Its role in malignant progression and immunotherapy
Biomed Pharmacother. 2023 Sep 14;167:115514. doi: 10.1016/j.biopha.2023.115514. Online ahead of print.ABSTRACTProgrammed cell death protein-1 (PD-1), also called CD279, is coded by the PDCD1 gene and is constitutively expressed on the surface of immune cells. As a receptor and immune checkpoint, PD-1 can bind to programmed death ligand-1/programmed death ligand-2 (PD-L1/PD-L2) in tumor cells, leading to tumor immune evasion. Anti-PD-1 and anti-PD-L1 are important components in tumor immune therapy. PD-1 is also expressed as an intrinsic variant (iPD-1) in cancer cells where it plays important roles in malignant progression...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 16, 2023 Category: Drugs & Pharmacology Authors: Muhua Chen Lei Bie Jieer Ying Source Type: research
Molecular subtypes and prognostic models for predicting prognosis of lung adenocarcinoma based on miRNA-related genes
CONCLUSION: Such miRNA-associated target gene characterization could be useful for prognostic prediction and contribute to therapeutic decision-making in LUAD.PMID:37711127 | DOI:10.2174/0929867331666230914151943
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Yuxi Wei Wei Zhong Yalan Bi Xiaoyan Liu Qing Zhou Jia Liu Mengzhao Wang Hong Zhang Minjiang Chen Source Type: research
Screening of immune-related lncRNAs in lung adenocarcinoma and establishing a survival prognostic risk prediction model
CONCLUSION: We have established a promising LUAD patient survival prediction model based on six immune-related lncRNAs. For LUAD patients, this prognostic model could guide personalized treatment.PMID:37711103 | DOI:10.2174/1386207326666230913120523
Source: Combinatorial Chemistry and High Throughput Screening - September 15, 2023 Category: Chemistry Authors: Wenxia Jiang Xuyou Zhu Jiaqi Bo Jun Ma Source Type: research
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma
Cancer Biol Ther. 2023 Dec 31;24(1):2253586. doi: 10.1080/15384047.2023.2253586.ABSTRACTLung adenocarcinoma is one of the leading causes of cancer-related mortality globally. Various treatment approaches and drugs had little influence on overall survival; thus, new drugs and treatment strategies are needed. Drug repositioning (repurposing) seems a favorable approach considering that developing new drugs needs much more time and costs. We performed a meta-analysis on 6 microarray datasets to obtain the main genes with significantly altered expression in lung adenocarcinoma. Following that, we found major gene clusters and h...
Source: Cancer Biology and Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Liora Yesharim Shahram Teimourian Source Type: research
Socioeconomic status and cecal adenocarcinoma mortality risk: an American population-based analysis
CONCLUSION: Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.PMID:37712280 | DOI:10.12122/j.issn.1673-4254.2023.08.20
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Shao J Lyu Source Type: research
Screening of immune-related lncRNAs in lung adenocarcinoma and establishing a survival prognostic risk prediction model
CONCLUSION: We have established a promising LUAD patient survival prediction model based on six immune-related lncRNAs. For LUAD patients, this prognostic model could guide personalized treatment.PMID:37711103 | DOI:10.2174/1386207326666230913120523
Source: Combinatorial Chemistry and High Throughput Screening - September 15, 2023 Category: Chemistry Authors: Wenxia Jiang Xuyou Zhu Jiaqi Bo Jun Ma Source Type: research
Socioeconomic status and cecal adenocarcinoma mortality risk: an American population-based analysis
CONCLUSION: Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.PMID:37712280 | PMC:PMC10505572 | DOI:10.12122/j.issn.1673-4254.2023.08.20
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Shao J Lyu Source Type: research
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma
Cancer Biol Ther. 2023 Dec 31;24(1):2253586. doi: 10.1080/15384047.2023.2253586.ABSTRACTLung adenocarcinoma is one of the leading causes of cancer-related mortality globally. Various treatment approaches and drugs had little influence on overall survival; thus, new drugs and treatment strategies are needed. Drug repositioning (repurposing) seems a favorable approach considering that developing new drugs needs much more time and costs. We performed a meta-analysis on 6 microarray datasets to obtain the main genes with significantly altered expression in lung adenocarcinoma. Following that, we found major gene clusters and h...
Source: Cancer Biology and Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Liora Yesharim Shahram Teimourian Source Type: research
Socioeconomic status and cecal adenocarcinoma mortality risk: an American population-based analysis
CONCLUSION: Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.PMID:37712280 | PMC:PMC10505572 | DOI:10.12122/j.issn.1673-4254.2023.08.20
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Shao J Lyu Source Type: research
Drug repurposing based on differentially expressed genes suggests drug combinations with possible synergistic effects in treatment of lung adenocarcinoma
Cancer Biol Ther. 2023 Dec 31;24(1):2253586. doi: 10.1080/15384047.2023.2253586.ABSTRACTLung adenocarcinoma is one of the leading causes of cancer-related mortality globally. Various treatment approaches and drugs had little influence on overall survival; thus, new drugs and treatment strategies are needed. Drug repositioning (repurposing) seems a favorable approach considering that developing new drugs needs much more time and costs. We performed a meta-analysis on 6 microarray datasets to obtain the main genes with significantly altered expression in lung adenocarcinoma. Following that, we found major gene clusters and h...
Source: Cancer Biology and Therapy - September 15, 2023 Category: Cancer & Oncology Authors: Liora Yesharim Shahram Teimourian Source Type: research
Screening of immune-related lncRNAs in lung adenocarcinoma and establishing a survival prognostic risk prediction model
CONCLUSION: We have established a promising LUAD patient survival prediction model based on six immune-related lncRNAs. For LUAD patients, this prognostic model could guide personalized treatment.PMID:37711103 | DOI:10.2174/1386207326666230913120523
Source: Combinatorial Chemistry and High Throughput Screening - September 15, 2023 Category: Chemistry Authors: Wenxia Jiang Xuyou Zhu Jiaqi Bo Jun Ma Source Type: research
Molecular subtypes and prognostic models for predicting prognosis of lung adenocarcinoma based on miRNA-related genes
CONCLUSION: Such miRNA-associated target gene characterization could be useful for prognostic prediction and contribute to therapeutic decision-making in LUAD.PMID:37711127 | DOI:10.2174/0929867331666230914151943
Source: Current Medicinal Chemistry - September 15, 2023 Category: Chemistry Authors: Yuxi Wei Wei Zhong Yalan Bi Xiaoyan Liu Qing Zhou Jia Liu Mengzhao Wang Hong Zhang Minjiang Chen Source Type: research
