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Cancer: Adenocarcinoma
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Total 24759 results found since Jan 2013.
With Comparable Outcomes, Should Early Stage Lung Cancer Be A Contraindication to Lung Transplant?
CONCLUSIONS: One- and 5-year survival rates were comparable between LTx recipients with incidentally noted pathological Stage I NSCLC and contemporary recipients without cancer. All cancer-related mortality occurred in recipients with incidentally noted advanced NSCLC. These results suggest that patients with pathological Stage I lung cancer at the time of transplant have outcomes comparable to those without cancer findings at the time of transplant.PMID:37704001 | DOI:10.1016/j.athoracsur.2023.09.002
Source: The Annals of Thoracic Surgery - September 13, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Connor S Spies Timothy N Ochoa Arya Pontula Chelsea S Harris Laurie D Snyder Elizabeth N Pavlisko Matthew G Hartwig Source Type: research
Correlation of microsatellite status and EBV infection with clinical characteristics of patients with gastric cancer
This study was designed to investigate the correlation of microsatellite status (MS) and Epstein-Barr virus (EBV) infection with the clinical characteristics of gastric cancer (GC) patients. MS was detected by immunohistochemistry. EBV was detected by in situ hybridization. There were 31.3% cases showed mismatch repair-deficient (dMMR)/ microsatellite instability (MSI) and 68.7% cases showed mismatch repair-proficient (pMMR)/ microsatellite stability (MSS). The dMMR/MSI was more common in the elderly, in patients with cardia GC, smaller tumor diameter or non-poorly differentiated carcinoma. The survival in dMMR/MSI patient...
Source: General Physiology and Biophysics - September 13, 2023 Category: Physiology Authors: Pengfei Lu Kadeliya Yushan Gulimilai Yusufu Hiu Wang Rui Mao Source Type: research
DOCK4 is a novel prognostic biomarker and correlated with immune infiltrates in colon adenocarcinoma
CONCLUSIONS: DOCK4 potentially plays an important role in the regulation of TME in COAD. DOCK4 facilitates the development through the Rap1A pathway, thus becoming a novel prognostic biomarker in COAD.PMID:37702239 | DOI:10.2174/1386207326666230912094101
Source: Combinatorial Chemistry and High Throughput Screening - September 13, 2023 Category: Chemistry Authors: Xingjiang Xie Yi Lu Bo Wang Xiaobin Yin Jianfeng Chen Source Type: research
Correlation of microsatellite status and EBV infection with clinical characteristics of patients with gastric cancer
This study was designed to investigate the correlation of microsatellite status (MS) and Epstein-Barr virus (EBV) infection with the clinical characteristics of gastric cancer (GC) patients. MS was detected by immunohistochemistry. EBV was detected by in situ hybridization. There were 31.3% cases showed mismatch repair-deficient (dMMR)/ microsatellite instability (MSI) and 68.7% cases showed mismatch repair-proficient (pMMR)/ microsatellite stability (MSS). The dMMR/MSI was more common in the elderly, in patients with cardia GC, smaller tumor diameter or non-poorly differentiated carcinoma. The survival in dMMR/MSI patient...
Source: General Physiology and Biophysics - September 13, 2023 Category: Physiology Authors: Pengfei Lu Kadeliya Yushan Gulimilai Yusufu Hiu Wang Rui Mao Source Type: research
Presentation of Gastrointestinal Stromal Tumor, Pancreatic Adenocarcinoma, and Gastric Adenocarcinoma in a Woman With No Identifiable Genetic Abnormalities
This report details the first known case of co-occurrence of gastrointestinal stromal tumor (GIST), pancreatic adenocarcinoma, and gastric adenocarcinoma in an individual with no identifiable genetic abnormalities. The patient is a 57-year-old female who presented with abdominal pain. CT scan demonstrated a pancreatic mass, and endoscopic ultrasound demonstrated an additional gastric mass. Biopsy of both masses demonstrated adenocarcinoma; however, the masses were found to have different origins. The patient underwent neoadjuvant chemotherapy with excellent response. She then underwent surgical intervention, which demonstr...
Source: The American Surgeon - September 12, 2023 Category: Surgery Authors: Catherine Read Marybeth Hughes Omar Itani Source Type: research
Prognostic and immune correlation analysis of mitochondrial autophagy and aging-related genes in lung adenocarcinoma
CONCLUSIONS: Seven MiAg-related genes were identified to be significantly associated with the prognosis of patients diagnosed with LUAD. Moreover, the identified MiAg DEGs might affect the immunotherapy strategy of patients with LUAD.PMID:37698683 | DOI:10.1007/s00432-023-05390-x
Source: Clinical Lung Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Xiangzhi Meng Weijian Song Boxuan Zhou Mei Liang Yushun Gao Source Type: research
The potential role of osteoporosis in unspecific < sup > 18 < /sup > FPSMA-1007 bone uptake
CONCLUSIONS: We observed unspecific bone uptake on [18F]PSMA-1007 PET in more than 1/3 of patients. In this exploratory analysis, we found a significant correlation between blood count parameters and unspecific [18F]PSMA-1007 bone uptake. We may speculate that [18F]PSMA-1007 unspecific bone uptake could be associated with osteoporosis. This hypothesis needs to be further investigated in larger populations and exploring more specific markers of osteoporosis.PMID:37698646 | DOI:10.1007/s00259-023-06424-9
Source: Molecular Medicine - September 12, 2023 Category: Molecular Biology Authors: Gaia Ninatti Cristiano Pini Fabrizia Gelardi Samuele Ghezzo Paola Mapelli Maria Picchio Lidija Antunovic Alberto Briganti Francesco Montorsi Claudio Landoni Martina Sollini Arturo Chiti Source Type: research
A novel cuproptosis-related gene prognostic signature in colon adenocarcinoma
This study plans to establish a survival prognosis model for colon adenocarcinoma (COAD) patients based on cuproptosis-related genes (CRGs). We investigated the genetic alterations of CRGs in COAD based on The Cancer Genome Atlas database and validated in the GSE41328 dataset. Our results showed that LIPT1, PDHA1, GLS, and CDKN2A had significantly higher expression in COAD tissues than in normal tissues, while FDX1, DLD, and MTF1 had significantly lower expression in COAD tissues than in normal tissues (|(log2(fold change))| > 2, p < 0.05). DLD (hazard ratio (HR): 0.658; 95% confidence interval (CI): 0.445, 0.974; p ...
Source: Canadian Journal of Physiology and Pharmacology - September 12, 2023 Category: Drugs & Pharmacology Authors: Yongqin Su Kun Zhang Source Type: research
Prognostic and immune correlation analysis of mitochondrial autophagy and aging-related genes in lung adenocarcinoma
CONCLUSIONS: Seven MiAg-related genes were identified to be significantly associated with the prognosis of patients diagnosed with LUAD. Moreover, the identified MiAg DEGs might affect the immunotherapy strategy of patients with LUAD.PMID:37698683 | DOI:10.1007/s00432-023-05390-x
Source: Clinical Lung Cancer - September 12, 2023 Category: Cancer & Oncology Authors: Xiangzhi Meng Weijian Song Boxuan Zhou Mei Liang Yushun Gao Source Type: research
Clear Cell Adenocarcinoma of Urethra: Clinical and Pathologic Implications and Characterization of Molecular Aberrations
CONCLUSION: Our findings shed light on the molecular background of this extremely rare tumor with poor prognosis and can help improve treatment options.PMID:37697729 | DOI:10.4143/crt.2023.577
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Boram Song Seok Hyun Lee Jeong Hwan Park Kyung Chul Moon Source Type: research
Impact of oophorectomy on survival and improving nutritional status in ovarian metastasis from colorectal adenocarcinoma
CONCLUSIONS: Oophorectomy for ovarian metastasis from colorectal cancers was safely performed. It improved the patients' symptoms and nutritional status and may result in improved prognosis.PMID:37699374 | DOI:10.1159/000533599
Source: Oncology - September 12, 2023 Category: Cancer & Oncology Authors: Yusuke Miyagawa Masato Kitazawa Shigeo Tokumaru Satoshi Nakamura Makoto Koyama Yuta Yamamoto Satoru Miyazaki Nao Hondo Yuji Soejima Source Type: research
