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Infectious Disease: Endemics
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Total 16462 results found since Jan 2013.
microRNA silencing in a whole worm cestode model provides insight into miR-71 function
This study provides new knowledge on gene expression regulation in cestodes and suggests that miRNAs could be evaluated as new selective therapeutic targets for treating Neglected Tropical Diseases prioritised by the World Health Organization.PMID:37699506 | DOI:10.1016/j.ijpara.2023.08.002
Source: International Journal for Parasitology - September 12, 2023 Category: Parasitology Authors: Andr és Grecco Natalia Macchiaroli Mat ías Pérez Adriano Casulli Marcela Cucher Mara Cecilia Rosenzvit Source Type: research
Biting rhythms and infection rates of anthropophilic sand fly species (Diptera: Phlebotominae) in sites with different land use in southern Mexico
Acta Trop. 2023 Sep 9:107014. doi: 10.1016/j.actatropica.2023.107014. Online ahead of print.ABSTRACTCould tropical forest conversion shape sand fly (Diptera: Phlebotominae) biting rhythms and Leishmania infection rates? Using a Shannon trap, we estimated the bite rate and infection prevalence among anthropophilic sand flies at sites with different land use in southern Mexico. We estimated the expected monthly infection rate of the Leishmania parasite along the gradient and generated information on the biting rhythm of sand flies in a poorly characterized cutaneous leishmaniasis endemic region. We used generalized mixed lin...
Source: Acta Tropica - September 11, 2023 Category: Infectious Diseases Authors: A C Montes de Oca-Aguilar M I Pav ón-Mendez K B L ópez-Ávila E I Sosa-Bibiano E A Rebollar-T éllez J A Palacio-Vargas E A Fern ández-Figueroa E N Lor ía-Cervera Source Type: research
Improving mycetoma case detection through the training of community health workers in Northern Uganda: protocol for a stepped-wedge cluster-randomized trial
Ther Adv Infect Dis. 2023 Sep 8;10:20499361231198332. doi: 10.1177/20499361231198332. eCollection 2023 Jan-Dec.ABSTRACTINTRODUCTION: The World Health Organization acknowledges the need for countries to incorporate neglected tropical disease care into their routine health care system. However, low detection rates and late presentation of mycetoma to health facilities have been observed in endemic countries, including Uganda.OBJECTIVE: To empower community health workers (CHWs) in Northern Uganda to recognize and refer suspects of mycetoma to health facilities.DESIGN: This will be a stepped-wedge cluster-randomized trial bas...
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Winnie Kibone Andrew Weil Semulimi Richard Kwizera Felix Bongomin Source Type: research
Case Report: Nocardia amamiensis Infection Leading to Worsening of Chronic Obstructive Pulmonary Disease Symptoms in an Elderly Man
Am J Trop Med Hyg. 2023 Sep 11:tpmd230284. doi: 10.4269/ajtmh.23-0284. Online ahead of print.ABSTRACTNocardiosis is a rare opportunistic infection mostly affecting the lungs, brain, or skin of immunocompromised individuals. Most pulmonary nocardiosis patients present with nonspecific clinical features such as productive cough, exertional dyspnea, and fever. The disease is uncommonly suspected, especially in tuberculosis-endemic regions, and clinical diagnosis is often delayed, resulting in high mortality. Pulmonary nocardiosis in apparently immunocompetent individuals is uncommon. Here, we present the case of an elderly ge...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Ahalya Kanakan Amit Kumar Upinder Kaur Prity Narwade Zinnu Rain Nidhi Yadav Ishan Kumar Deepak Kumar Sankha Shubhra Chakrabarti Source Type: research
Integrated Prevalence Assessment of Wuchereria bancrofti and Onchocerca volvulus in Three Co-Endemic Districts of Gambella Region, Ethiopia
Am J Trop Med Hyg. 2023 Sep 11:tpmd220392. doi: 10.4269/ajtmh.22-0392. Online ahead of print.ABSTRACTLymphatic filariasis (LF) and onchocerciasis (OV) are among the neglected tropical diseases (NTD) targeted for elimination in Ethiopia. We used a transmission assessment survey (TAS-1) to evaluate the serological status of OV in three co-endemic districts in Gambella simultaneously. During May and June 2019, blood samples were collected from 6- to 7-year-old children who were randomly selected through standard community-based TAS methodology. Children were tested for both circulating filarial antigen (CFA) for LF via filari...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Mohammed Hassen Aderajew Mohammed Tekola Endeshaw Tewodros Seid Fikresilasie Samuel Tadese Asmare Henok Birhanu Firdaweke Bekele Adane Yayeh Fikre Seife Mossie Tamiru Kadu Meribo Zerihun Tadesse Emily Griswold Moses Katabarwa Frank Richards Gregory S Nola Source Type: research
Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis
Am J Trop Med Hyg. 2023 Sep 11:tpmd230361. doi: 10.4269/ajtmh.23-0361. Online ahead of print.ABSTRACTChagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms. This was a U.S.-based, multicenter, population-based, retrospective cohort study. We queried TriNetX, a global research network, to identify patients with dual-positive IgG serology for Trypanosoma cruzi. We captured outcomes of interest for up to 5 years. We found 429 patients with evidence of dual-positive T. cr...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Andr és F Henao-Martínez Christian Olivo-Freites Nelson I Agudelo Higuita Carolina Ferraz Carlos Franco-Paredes Jose Tuells Laila Woc-Colburn Salvador Villalpando-Carri ón Daniel B Chastain Anis Rassi Source Type: research
Case Report: Nocardia amamiensis Infection Leading to Worsening of Chronic Obstructive Pulmonary Disease Symptoms in an Elderly Man
Am J Trop Med Hyg. 2023 Sep 11:tpmd230284. doi: 10.4269/ajtmh.23-0284. Online ahead of print.ABSTRACTNocardiosis is a rare opportunistic infection mostly affecting the lungs, brain, or skin of immunocompromised individuals. Most pulmonary nocardiosis patients present with nonspecific clinical features such as productive cough, exertional dyspnea, and fever. The disease is uncommonly suspected, especially in tuberculosis-endemic regions, and clinical diagnosis is often delayed, resulting in high mortality. Pulmonary nocardiosis in apparently immunocompetent individuals is uncommon. Here, we present the case of an elderly ge...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Ahalya Kanakan Amit Kumar Upinder Kaur Prity Narwade Zinnu Rain Nidhi Yadav Ishan Kumar Deepak Kumar Sankha Shubhra Chakrabarti Source Type: research
Integrated Prevalence Assessment of Wuchereria bancrofti and Onchocerca volvulus in Three Co-Endemic Districts of Gambella Region, Ethiopia
Am J Trop Med Hyg. 2023 Sep 11:tpmd220392. doi: 10.4269/ajtmh.22-0392. Online ahead of print.ABSTRACTLymphatic filariasis (LF) and onchocerciasis (OV) are among the neglected tropical diseases (NTD) targeted for elimination in Ethiopia. We used a transmission assessment survey (TAS-1) to evaluate the serological status of OV in three co-endemic districts in Gambella simultaneously. During May and June 2019, blood samples were collected from 6- to 7-year-old children who were randomly selected through standard community-based TAS methodology. Children were tested for both circulating filarial antigen (CFA) for LF via filari...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Mohammed Hassen Aderajew Mohammed Tekola Endeshaw Tewodros Seid Fikresilasie Samuel Tadese Asmare Henok Birhanu Firdaweke Bekele Adane Yayeh Fikre Seife Mossie Tamiru Kadu Meribo Zerihun Tadesse Emily Griswold Moses Katabarwa Frank Richards Gregory S Nola Source Type: research
Case Report: Nocardia amamiensis Infection Leading to Worsening of Chronic Obstructive Pulmonary Disease Symptoms in an Elderly Man
Am J Trop Med Hyg. 2023 Sep 11:tpmd230284. doi: 10.4269/ajtmh.23-0284. Online ahead of print.ABSTRACTNocardiosis is a rare opportunistic infection mostly affecting the lungs, brain, or skin of immunocompromised individuals. Most pulmonary nocardiosis patients present with nonspecific clinical features such as productive cough, exertional dyspnea, and fever. The disease is uncommonly suspected, especially in tuberculosis-endemic regions, and clinical diagnosis is often delayed, resulting in high mortality. Pulmonary nocardiosis in apparently immunocompetent individuals is uncommon. Here, we present the case of an elderly ge...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Ahalya Kanakan Amit Kumar Upinder Kaur Prity Narwade Zinnu Rain Nidhi Yadav Ishan Kumar Deepak Kumar Sankha Shubhra Chakrabarti Source Type: research
Integrated Prevalence Assessment of Wuchereria bancrofti and Onchocerca volvulus in Three Co-Endemic Districts of Gambella Region, Ethiopia
Am J Trop Med Hyg. 2023 Sep 11:tpmd220392. doi: 10.4269/ajtmh.22-0392. Online ahead of print.ABSTRACTLymphatic filariasis (LF) and onchocerciasis (OV) are among the neglected tropical diseases (NTD) targeted for elimination in Ethiopia. We used a transmission assessment survey (TAS-1) to evaluate the serological status of OV in three co-endemic districts in Gambella simultaneously. During May and June 2019, blood samples were collected from 6- to 7-year-old children who were randomly selected through standard community-based TAS methodology. Children were tested for both circulating filarial antigen (CFA) for LF via filari...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Mohammed Hassen Aderajew Mohammed Tekola Endeshaw Tewodros Seid Fikresilasie Samuel Tadese Asmare Henok Birhanu Firdaweke Bekele Adane Yayeh Fikre Seife Mossie Tamiru Kadu Meribo Zerihun Tadesse Emily Griswold Moses Katabarwa Frank Richards Gregory S Nola Source Type: research
Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis
Am J Trop Med Hyg. 2023 Sep 11:tpmd230361. doi: 10.4269/ajtmh.23-0361. Online ahead of print.ABSTRACTChagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms. This was a U.S.-based, multicenter, population-based, retrospective cohort study. We queried TriNetX, a global research network, to identify patients with dual-positive IgG serology for Trypanosoma cruzi. We captured outcomes of interest for up to 5 years. We found 429 patients with evidence of dual-positive T. cr...
Source: The American Journal of Tropical Medicine and Hygiene - September 11, 2023 Category: Tropical Medicine Authors: Andr és F Henao-Martínez Christian Olivo-Freites Nelson I Agudelo Higuita Carolina Ferraz Carlos Franco-Paredes Jose Tuells Laila Woc-Colburn Salvador Villalpando-Carri ón Daniel B Chastain Anis Rassi Source Type: research
Improving mycetoma case detection through the training of community health workers in Northern Uganda: protocol for a stepped-wedge cluster-randomized trial
Ther Adv Infect Dis. 2023 Sep 8;10:20499361231198332. doi: 10.1177/20499361231198332. eCollection 2023 Jan-Dec.ABSTRACTINTRODUCTION: The World Health Organization acknowledges the need for countries to incorporate neglected tropical disease care into their routine health care system. However, low detection rates and late presentation of mycetoma to health facilities have been observed in endemic countries, including Uganda.OBJECTIVE: To empower community health workers (CHWs) in Northern Uganda to recognize and refer suspects of mycetoma to health facilities.DESIGN: This will be a stepped-wedge cluster-randomized trial bas...
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Winnie Kibone Andrew Weil Semulimi Richard Kwizera Felix Bongomin Source Type: research
