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Infectious Disease: Endemics
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Total 16462 results found since Jan 2013.
GMP manufacture of Shigella flexneri 2a Artificial Invaplex (Invaplex < sub > AR < /sub > ) and evaluation in a Phase 1 Open-label, dose escalating study administered intranasally to healthy, adult volunteers
Vaccine. 2023 Sep 2:S0264-410X(23)00995-7. doi: 10.1016/j.vaccine.2023.08.051. Online ahead of print.ABSTRACTShigella species cause severe disease among travelers to, and children living in, endemic countries. Although significant efforts have been made to improve sanitation, increased antibiotic resistance and other factors suggest an effective vaccine is a critical need. Artificial Invaplex (InvaplexAR) is a subunit vaccine approach complexing Shigella LPS with invasion plasmid antigens. In pre-clinical studies, the InvaplexAR vaccine demonstrated increased immunogenicity as compared to the first generation product and w...
Source: Vaccine - September 4, 2023 Category: Allergy & Immunology Authors: Christopher Duplessis Kristen A Clarkson K Ross Turbyfill Ashley N Alcala Ramiro Gutierrez Mark S Riddle Tida Lee Kristopher Paolino Hailey P Weerts Amanda Lynen Edwin V Oaks Chad K Porter Robert Kaminski Source Type: research
Social construction of risk and prevention practices related to Aedes mosquito-borne disease in an endemic municipality in Colombia
CONCLUSION: The findings show a multisituated risk that refers to the inside and outside of homes; and the prevention practices mentioned by different actors, in which a continuity of tensions between lay people, leaders and government officials can be observed.PMID:37666503 | DOI:10.22605/RRH7695
Source: Rural Remote Health - September 4, 2023 Category: Rural Health Authors: Claudia Margarita Cort és García Claudia Milena Hormiga S ánchez Johan Sebasti án Ariza Abril Yaneth Stefania Becerra Fajardo Source Type: research
Roaming behavior of the owned domestic cats (Felis catus) with possible roles in the transmission of Opisthorchis viverrini in the endemic area in Khon Kaen, Thailand
Acta Trop. 2023 Sep 1:107013. doi: 10.1016/j.actatropica.2023.107013. Online ahead of print.ABSTRACTIn the endemic area of the liver fluke (Opisthorchis viverrini) infection, effective control of opisthorchiasis using One Health approaches requires transmission interruption in all hosts in the parasite life cycle. Owned domestic cats (Felis catus) are considered an important species among mammalian reservoirs. Similar to humans, household cats become infected by eating raw, contaminated fish and spread the O. viverrini eggs to the environment by defecation. In rural areas, cat owners usually feed their cats with human food...
Source: Acta Tropica - September 3, 2023 Category: Infectious Diseases Authors: Makoto Sakamoto Songkiad Upontain Pornphutthachat Sota Jeffrey Mariner Prasarn Tangkawattana Sirikachorn Tangkawattana Source Type: research
A multi-resistant bacterium before the era of antibiotics : the agent of melioidosis
C R Biol. 2023 Aug 31. doi: 10.5802/crbiol.109. Online ahead of print.ABSTRACTMelioidosis is an infectious, tropical and emerging disease, due to a bacterium of the hydrotelluric environment, Burkholderia pseudomallei, which is considered as a potential biological weapon because of its exceptional resistance and virulence capacities. Its worldwide spread, outside the original endemic foci of Southeast Asia and Australia, is favoured by global warming and the diabetes mellitus pandemic, which is the main predisposing factor.In humans, melioidosis is an opportunistic infection, following professional (rice farmers, soldiers)...
Source: Comptes Rendus Biologies - September 1, 2023 Category: Biology Authors: Yves Buisson Source Type: research
Genomic epidemiology unveils the dynamics and spatial corridor behind the Yellow Fever virus outbreak in Southern Brazil
This study illustrates that genomics linked with eco-epidemiology can provide new insights into the landscape of YFV transmission, augmenting traditional approaches to infectious disease surveillance and control.PMID:37656782 | DOI:10.1126/sciadv.adg9204
Source: Adv Data - September 1, 2023 Category: Epidemiology Authors: Marta Giovanetti Francesco Pinotti Camila Zanluca Vagner Fonseca Taishi Nakase Andrea C Koishi Marcel Tscha Guilherme Soares Gisiane Gruber Dorl Ant ônio Ernesto M L Marques Renato Sousa Talita Emile Ribeiro Adelino Joilson Xavier Carla de Oliveira Sandr Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
A multi-resistant bacterium before the era of antibiotics : the agent of melioidosis
C R Biol. 2023 Aug 31. doi: 10.5802/crbiol.109. Online ahead of print.ABSTRACTMelioidosis is an infectious, tropical and emerging disease, due to a bacterium of the hydrotelluric environment, Burkholderia pseudomallei, which is considered as a potential biological weapon because of its exceptional resistance and virulence capacities. Its worldwide spread, outside the original endemic foci of Southeast Asia and Australia, is favoured by global warming and the diabetes mellitus pandemic, which is the main predisposing factor.In humans, melioidosis is an opportunistic infection, following professional (rice farmers, soldiers)...
Source: Comptes Rendus Biologies - September 1, 2023 Category: Biology Authors: Yves Buisson Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
Genomic epidemiology unveils the dynamics and spatial corridor behind the Yellow Fever virus outbreak in Southern Brazil
This study illustrates that genomics linked with eco-epidemiology can provide new insights into the landscape of YFV transmission, augmenting traditional approaches to infectious disease surveillance and control.PMID:37656782 | DOI:10.1126/sciadv.adg9204
Source: Adv Data - September 1, 2023 Category: Epidemiology Authors: Marta Giovanetti Francesco Pinotti Camila Zanluca Vagner Fonseca Taishi Nakase Andrea C Koishi Marcel Tscha Guilherme Soares Gisiane Gruber Dorl Ant ônio Ernesto M L Marques Renato Sousa Talita Emile Ribeiro Adelino Joilson Xavier Carla de Oliveira Sandr Source Type: research
A multi-resistant bacterium before the era of antibiotics : the agent of melioidosis
C R Biol. 2023 Aug 31. doi: 10.5802/crbiol.109. Online ahead of print.ABSTRACTMelioidosis is an infectious, tropical and emerging disease, due to a bacterium of the hydrotelluric environment, Burkholderia pseudomallei, which is considered as a potential biological weapon because of its exceptional resistance and virulence capacities. Its worldwide spread, outside the original endemic foci of Southeast Asia and Australia, is favoured by global warming and the diabetes mellitus pandemic, which is the main predisposing factor.In humans, melioidosis is an opportunistic infection, following professional (rice farmers, soldiers)...
Source: Comptes Rendus Biologies - September 1, 2023 Category: Biology Authors: Yves Buisson Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
A multi-resistant bacterium before the era of antibiotics : the agent of melioidosis
C R Biol. 2023 Aug 31. doi: 10.5802/crbiol.109. Online ahead of print.ABSTRACTMelioidosis is an infectious, tropical and emerging disease, due to a bacterium of the hydrotelluric environment, Burkholderia pseudomallei, which is considered as a potential biological weapon because of its exceptional resistance and virulence capacities. Its worldwide spread, outside the original endemic foci of Southeast Asia and Australia, is favoured by global warming and the diabetes mellitus pandemic, which is the main predisposing factor.In humans, melioidosis is an opportunistic infection, following professional (rice farmers, soldiers)...
Source: Comptes Rendus Biologies - September 1, 2023 Category: Biology Authors: Yves Buisson Source Type: research
T helper type 9 cell response and its role in the neurological clinic of patients with Human T-lymphotropic virus 1
This study aimed to evaluate the expression profiles of PU.1, interferon regulatory factor 4 (IRF-4), and cytokine interleukin-9 (IL-9) during the induction of peripheral immune response and their role in the HTLV-1-infected patients' neurological symptoms. This analytical cross-sectional study was carried out at the Laboratory of Clinical and Epidemiology of Endemic Diseases and the Laboratory of Immunopathology, both from the Tropical Medicine Center at the Federal University of Pará. Assessment of neurological parameters was performed (gait, Expanded Kurtzke Disability State Scale (EDSS) score, upper and lower limb ref...
Source: Immunobiology - September 1, 2023 Category: Allergy & Immunology Authors: Roberto de Sena Rodrigues J únior J éssica Antonia Nunes Gomes George Alberto da Silva Dias Satomi Fujihara Gilberto Toshimitsu Yoshikawa Roberta Vilela Lopes Koyama Rita Catarina Medeiros Sousa Juarez Antonio Sim ões Quaresma Hellen Thais Fuzii Source Type: research
