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Procedure: Perfusion
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The Impact of Aging on Vascular Ion Channels: Perspectives and Knowledge Gaps Across Major Organ Systems
Am J Physiol Heart Circ Physiol. 2023 Aug 25. doi: 10.1152/ajpheart.00288.2023. Online ahead of print.ABSTRACTIndividuals aged ≥65 years will comprise approximately 20% of the global population by 2030. Cardiovascular disease remains the leading cause of death in the world with age-related endothelial "dysfunction" as a key risk factor. As an organ in and of itself, vascular endothelium courses throughout the mammalian body to coordinate blood flow to all other organs and tissues (e.g., brain, heart, lung, skeletal muscle, gut, kidney, skin) in accord with metabolic demand. In turn, emerging evidence demonstrates that va...
Source: American Journal of Physiology. Heart and Circulatory Physiology - August 25, 2023 Category: Physiology Authors: Erik J Behringer Source Type: research
Diagnostical accuracy of hyperspectral imaging after free flap surgery
This study aimed to analyze the diagnostic accuracy of hyperspectral imaging (HSI) after free-tissue transfer surgery. From January 2017 to October 2019, 42 consecutive free-flap surgeries were performed, and their outcomes were analyzed via HSI. Clinical examination of free-flap perfusion was initially performed. Clinical examination findings were subsequently compared with those of HSI. Potential venous congestion with subsequent necrosis was defined as a tissue hemoglobin index of ≥53%. Student's t-test was used to compare the results of the analysis. The evaluation of sensitivity and specificity for flap failure dete...
Source: Hand Surgery - August 24, 2023 Category: Surgery Authors: Torsten Schulz Rima Nuwayhida Khosrow Siamak Houschyar Stefan Langer Lukas Kohler Source Type: research
Infrared thermography is a novel tool to assess small intestinal surface temperature in dogs undergoing laparotomy for foreign body obstruction
Am J Vet Res. 2023 Aug 28:1-9. doi: 10.2460/ajvr.23.04.0082. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate local temperature differences directly over and adjacent to small intestinal foreign body obstruction (FBO) using infrared thermography (IRT) in dogs.ANIMALS: 49 client-owned dogs were initially enrolled.METHODS: In a prospective, clinical observational study, IRT was utilized to compare median small intestinal (SI) surface temperature differences at the site of FBO and segments oral and aboral before and after surgical resolution from April 24, 2019, to July 19, 2020. These differences were evaluated for corre...
Source: American Journal of Veterinary Research - August 24, 2023 Category: Veterinary Research Authors: Joanna B Finstad Edward Cooper Soscha C Ten Cate Page Yaxley Jiwoong Her Julien Guillaumin Source Type: research
Diagnostical accuracy of hyperspectral imaging after free flap surgery
This study aimed to analyze the diagnostic accuracy of hyperspectral imaging (HSI) after free-tissue transfer surgery. From January 2017 to October 2019, 42 consecutive free-flap surgeries were performed, and their outcomes were analyzed via HSI. Clinical examination of free-flap perfusion was initially performed. Clinical examination findings were subsequently compared with those of HSI. Potential venous congestion with subsequent necrosis was defined as a tissue hemoglobin index of ≥53%. Student's t-test was used to compare the results of the analysis. The evaluation of sensitivity and specificity for flap failure dete...
Source: Hand Surgery - August 24, 2023 Category: Surgery Authors: Torsten Schulz Rima Nuwayhida Khosrow Siamak Houschyar Stefan Langer Lukas Kohler Source Type: research
Method for comparison of data driven gating algorithms in emission tomography
Phys Med Biol. 2023 Aug 24. doi: 10.1088/1361-6560/acf3ce. Online ahead of print.ABSTRACTMultiple algorithms have been proposed for Data Driven Gating (DDG) in Single Photon Emission Computed Tomography (SPECT) and have successfully been applied to Myocardial Perfusion Imaging (MPI). Application of DDG to acquisition types other than SPECT MPI has not been demonstrated so far, as limitations and pitfalls of current methods are unknown. 

Approach: We create a comprehensive set of phantoms simulating the influence of different motion artifacts, view angles, moving objects, contrast, and count levels in SPECT...
Source: Physics in Medicine and Biology - August 24, 2023 Category: Physics Authors: Maximilian P Reymann A Hans Vija Andreas Maier Source Type: research
Infrared thermography is a novel tool to assess small intestinal surface temperature in dogs undergoing laparotomy for foreign body obstruction
Am J Vet Res. 2023 Aug 28:1-9. doi: 10.2460/ajvr.23.04.0082. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate local temperature differences directly over and adjacent to small intestinal foreign body obstruction (FBO) using infrared thermography (IRT) in dogs.ANIMALS: 49 client-owned dogs were initially enrolled.METHODS: In a prospective, clinical observational study, IRT was utilized to compare median small intestinal (SI) surface temperature differences at the site of FBO and segments oral and aboral before and after surgical resolution from April 24, 2019, to July 19, 2020. These differences were evaluated for corre...
Source: American Journal of Veterinary Research - August 24, 2023 Category: Veterinary Research Authors: Joanna B Finstad Edward Cooper Soscha C Ten Cate Page Yaxley Jiwoong Her Julien Guillaumin Source Type: research
Re-Dosing del Nido cardioplegia in adult cardiac surgery: Perfusion characteristics and outcomes--Is there an optimal redosing strategy?
CONCLUSIONS: In this retrospective study, variations in re-dosing strategy for del Nido cardioplegia do not affect postoperative outcomes and increased CPB time is associated with increased operative mortality, myocardial infarction, need for post-operative CSDs, and reduced postoperative EF, and increased VIS, irrespective of the re-dosing strategy. Further studies are warranted to to identify additional patient and operative characteristics that predispose to complications.PMID:37608700 | DOI:10.1177/02676591231197524
Source: Perfusion - August 23, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Alexander P Kossar Samantha Nemeth Yaagnik D Kosuri Brigitte E Kazzi Emily Honzel Alex D'Angelo Jessica Spellman Koji Takeda Hiroo Takayama Vinayak Bapat Michael Argenziano James Beck Craig R Smith Paul Kurlansky Isaac George Source Type: research
Efficacy of the Hepcon system in reducing hemorrhagic and thrombotic complications in antiphospholipid syndrome patients undergoing cardiac surgery
CONCLUSION: There was no difference in the composite outcome of thrombotic or hemorrhagic complications in patients monitored by Hepcon versus those monitored by ACT.PMID:37608561 | DOI:10.1177/02676591231197990
Source: Perfusion - August 23, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Sheu Michael Molina Garcia Sofia Wei Wei Grady Patrick Apostolakis John Angelini Dana Source Type: research
Saline bolus for negative contrast perfusion imaging in magnetic particle imaging
Phys Med Biol. 2023 Aug 22;68(17). doi: 10.1088/1361-6560/ace309.ABSTRACTObjective.Magnetic particle imaging (MPI) is capable of high temporal resolution measurements of the spatial distribution of magnetic nanoparticles and therefore well suited for perfusion imaging, which is an important tool in medical diagnosis. Perfusion imaging in MPI usually requires a fresh bolus of tracer material to capture the key signal dynamics. Here, we propose a method to decouple the imaging sequence from the injection of additional tracer material, without further increasing the administered iron dose in the body with each image.Approach....
Source: Physics in Medicine and Biology - August 23, 2023 Category: Physics Authors: Fabian Mohn Miriam Exner Patryk Szwargulski Martin M öddel Tobias Knopp Matthias Graeser Source Type: research
Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit
CONCLUSIONS: Taken together, we present transcriptional and functional evidence that the human placenta has an efficient 5-HT clearance system involving (1) removal of 5-HT from the fetal circulation by OCT3, (2) metabolism to 5-HIAA by MAO-A, and (3) selective 5-HIAA excretion to the maternal circulation via the MRP2 transporter. This synchronized mechanism is critical for regulating 5-HT in the fetoplacental unit; however, it can be compromised by external insults such as antidepressant drugs.PMID:37612712 | DOI:10.1186/s12958-023-01128-z
Source: Reproductive Biology - August 23, 2023 Category: Reproduction Medicine Authors: Frantisek Staud Xin Pan Rona Karahoda Xiaojing Dong Petr Kastner Hana Horackova Veronika Vachalova Udo R Markert Cilia Abad Source Type: research
Progress in molecular mechanisms of coronary microvascular dysfunction
Microcirculation. 2023 Aug 22:e12827. doi: 10.1111/micc.12827. Online ahead of print.ABSTRACTCoronary microvascular dysfunction is a high-risk factor for many cardiovascular events. However, because of multiple risk factors and limited understanding about its underlying pathophysiological mechanisms, it was easily misdiagnosed. Therefore, its clinical diagnosis and treatment were greatly restricted. Coronary microcirculation refers to microvessels that play an important role in the physiological regulation of myocardial perfusion and regulating blood flow distribution, fulfilling myocardial metabolic needs and moderating p...
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: Hao Li Yuping Gao Yuanyuan Lin Source Type: research
