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Procedure: Perfusion

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Total 15257 results found since Jan 2013.

Hydrogen Peroxide Affects the Electroretinogram of Isolated Perfused Rat Retina
CONCLUSIONS: H2O2 affects retinal function as shown by ERGs in isolated rat retina. The response differs with the dose of H2O2, suggesting that mechanisms underlying the action at low doses might be different from those at high doses. Our results also suggest an effect of H2O2 on ionic currents and/or neurotransmitter releases involved in the generation of the ERG and indicate a more pronounced effect on photoreceptors than on postsynaptic cells.PMID:37706511 | DOI:10.1080/02713683.2023.2256029
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Nathalie Jacquemot Eric Wersinger Philippe Brabet David Cia Source Type: research

Ambulatory extracorporeal membrane oxygenation simulator: The next frontier in clinical training
CONCLUSIONS: This paper will focus on presenting an overall ambulatory ECMO simulator, detailing the various sub-systems and emphasizing the modular casing of the physical components and the simulated patient monitor.PMID:37707960 | DOI:10.1177/02676591231201527
Source: Perfusion - September 14, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Aya N Sayed Mohammad Noorizadeh Yahya Alhomsi Faycal Bensaali Nader Meskin Ali Ait Hssain Source Type: research

Improving liver transplant outcomes with transplant-omics and network biology
Curr Opin Organ Transplant. 2023 Sep 13. doi: 10.1097/MOT.0000000000001100. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Molecular omics data is increasingly ubiquitous throughout medicine. In organ transplantation, recent large-scale research efforts are generating the 'transplant-ome' - the entire set of molecular omics data, including the genome, transcriptome, proteome, and metabolome. Importantly, early studies in anesthesiology have demonstrated how perioperative interventions alter molecular profiles in various patient populations. The next step for anesthesiologists and intensivists will be to tailor perioperat...
Source: Current Opinion in Organ Transplantation - September 14, 2023 Category: Transplant Surgery Authors: Joseph Scarpa Source Type: research

Ambulatory extracorporeal membrane oxygenation simulator: The next frontier in clinical training
CONCLUSIONS: This paper will focus on presenting an overall ambulatory ECMO simulator, detailing the various sub-systems and emphasizing the modular casing of the physical components and the simulated patient monitor.PMID:37707960 | DOI:10.1177/02676591231201527
Source: Perfusion - September 14, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Aya N Sayed Mohammad Noorizadeh Yahya Alhomsi Faycal Bensaali Nader Meskin Ali Ait Hssain Source Type: research

Improving liver transplant outcomes with transplant-omics and network biology
Curr Opin Organ Transplant. 2023 Sep 13. doi: 10.1097/MOT.0000000000001100. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Molecular omics data is increasingly ubiquitous throughout medicine. In organ transplantation, recent large-scale research efforts are generating the 'transplant-ome' - the entire set of molecular omics data, including the genome, transcriptome, proteome, and metabolome. Importantly, early studies in anesthesiology have demonstrated how perioperative interventions alter molecular profiles in various patient populations. The next step for anesthesiologists and intensivists will be to tailor perioperat...
Source: Current Opinion in Organ Transplantation - September 14, 2023 Category: Transplant Surgery Authors: Joseph Scarpa Source Type: research

Use of extracorporeal membrane oxygenation and cerebral oximetry in a stage 1 norwood repair for hypoplastic left heart syndrome
We report a case where the use of ECMO was beneficial after stage I Norwood palliation with severe ventricular dysfunction. The systemic-to-pulmonary artery shunt was kept open to balance the systemic and pulmonary circulations. Cerebral oximetry can be useful as an additional monitoring modality to guide management, monitor cerebral perfusion, and help detect cerebral steal.PMID:37706390 | PMC:PMC10284473 | DOI:10.4103/0971-9784.320955
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Anam A Kazi Kamlesh B Tailor M C Manoj Smruti Ranjan Mohanty Source Type: research

Hydrogen Peroxide Affects the Electroretinogram of Isolated Perfused Rat Retina
CONCLUSIONS: H2O2 affects retinal function as shown by ERGs in isolated rat retina. The response differs with the dose of H2O2, suggesting that mechanisms underlying the action at low doses might be different from those at high doses. Our results also suggest an effect of H2O2 on ionic currents and/or neurotransmitter releases involved in the generation of the ERG and indicate a more pronounced effect on photoreceptors than on postsynaptic cells.PMID:37706511 | DOI:10.1080/02713683.2023.2256029
Source: Current Eye Research - September 14, 2023 Category: Opthalmology Authors: Nathalie Jacquemot Eric Wersinger Philippe Brabet David Cia Source Type: research

Involvement of mitochondrial dynamics and mitophagy in diabetic endothelial dysfunction and cardiac microvascular injury
Arch Toxicol. 2023 Sep 14. doi: 10.1007/s00204-023-03599-w. Online ahead of print.ABSTRACTEndothelial cells (ECs), found in the innermost layer of blood vessels, are crucial for maintaining the structure and function of coronary microcirculation. Dysregulated coronary microcirculation poses a fundamental challenge in diabetes-related myocardial microvascular injury, impacting myocardial blood perfusion, thrombogenesis, and inflammation. Extensive research aims to understand the mechanistic connection and functional relationship between cardiac EC dysfunction and the development, diagnosis, and treatment of diabetes-related...
Source: Archives of Toxicology - September 14, 2023 Category: Toxicology Authors: Xiao Zhang Hao Zhou Xing Chang Source Type: research

Use of extracorporeal membrane oxygenation and cerebral oximetry in a stage 1 norwood repair for hypoplastic left heart syndrome
We report a case where the use of ECMO was beneficial after stage I Norwood palliation with severe ventricular dysfunction. The systemic-to-pulmonary artery shunt was kept open to balance the systemic and pulmonary circulations. Cerebral oximetry can be useful as an additional monitoring modality to guide management, monitor cerebral perfusion, and help detect cerebral steal.PMID:37706390 | PMC:PMC10284473 | DOI:10.4103/0971-9784.320955
Source: Annals of Cardiac Anaesthesia - September 14, 2023 Category: Anesthesiology Authors: Anam A Kazi Kamlesh B Tailor M C Manoj Smruti Ranjan Mohanty Source Type: research

Higher Body Mass Index is associated with increased arterial stiffness prior to target organ damage: a cross-sectional cohort study
CONCLUSION: Increased BMI is independently associated with augmented central arterial stiffness and reduced subendocardial perfusion but not with coronary artery disease, kidney function, or ABI.PMID:37710152 | DOI:10.1186/s12872-023-03503-5
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Nejc Piko Sebastjan Bevc Radovan Hojs Tadej Petreski Robert Ekart Source Type: research