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Procedure: Liver Transplant
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Total 13525 results found since Jan 2013.
Emerging therapeutic options for non-alcoholic fatty liver disease: A systematic review
CONCLUSION: The data analyzed in this review showed clinically significant improvement in individual histological features of NAFLD in both animal and human trials for all four classes, as well as good safety profiles (P < 0.05). We believe this compilation of information will have positive clinical implications in obtaining an FDA-approved therapy for NAFLD.PMID:37701920 | PMC:PMC10494562 | DOI:10.4254/wjh.v15.i8.1001
Source: World Journal of Hepatology - September 13, 2023 Category: Gastroenterology Authors: Jasmine Tidwell Natalie Balassiano Anjiya Shaikh Mahmoud Nassar Source Type: research
Auxiliary Partial Orthotopic Liver Transplant as a Rescue Procedure for Acute Liver Failure with Extra-Small-for-Size Grafts: A Report of 2 Cases
We present 2 cases of acute liver failure treated with auxiliary partial orthotopic liver transplant using an extra-small-for-size graft. The first case was a 12-year-old female patient who presented with druginduced acute liver failure and required an auxiliary partial orthotopic liver transplant with an extra-small left lobe graft (graft-to-recipient weight ratio of 0.45). The second case was a 23-year-old male patient with acute liver failure of unknown etiology who underwent an auxiliary partial orthotopic liver transplant with a small right lobe graft (graft-torecipient weight ratio of 0.5). In both cases, computed to...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Amith Kumar Pakkala Gaurav Chaubal Aditya Nanavati Hunaid Hatimi Rajeev Sinha Ameet Mandot Uday Sanglodkar Alisha Chaubal Harshit Chaksota Samir Shah Source Type: research
Living Donor Liver Transplantation in Patients with Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibodies Using Preoperative Desensitization Therapy According to Intensity of Donor-Specific Antibodies: A Single-Center Study
CONCLUSIONS Satisfactory LDLT results were achieved in DSA- and CREG-alone-positive cases following desensitization therapy.PMID:37697637 | DOI:10.12659/AOT.941346
Source: Annals of Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Kohei Ogawa Kei Tamura Katsunori Sakamoto Naotake Funamizu Masahiko Honjo Mikiya Shine Yusuke Nishi Tomoyuki Nagaoka Chihiro Ito Miku Iwata Mio Uraoka Yasutsugu Takada Source Type: research
Stimulator of interferon genes (STING): Key therapeutic targets in ischemia/reperfusion injury
Biomed Pharmacother. 2023 Sep 10;167:115458. doi: 10.1016/j.biopha.2023.115458. Online ahead of print.ABSTRACTThe Stimulator of Interferon Genes (STING) is predominantly expressed in immune cells, including macrophages, natural killer cells, dendritic cells, and T cells, functioning as a pattern recognition receptor. STING activation upon detecting cytosolic DNA released from damaged cells initiates downstream pathways, leading to the production of inflammatory cytokines such as IFNs, IL-6, and TNF-α. Dysregulated STING activation has been implicated in inflammatory and metabolic diseases. Ischemia/reperfusion injury (I/R...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 12, 2023 Category: Drugs & Pharmacology Authors: Juan Lv Xuanxuan Zhu Chunlei Xing Yuhong Chen Huihui Bian Heng Yin Xiaofeng Gu Li Su Source Type: research
Machine perfusion in liver transplantation
CONCLUSIONS: In situations where the decision has been made to transplant a liver donated after circulatory death or donated following brain death, end-ischaemic HOPE will provide superior clinically relevant outcomes compared with SCS alone. Specifically, graft survival is improved (high-certainty evidence), serious adverse events are reduced (moderate-certainty evidence), and in donors after circulatory death, clinically relevant ischaemic biliary complications are reduced (high-certainty evidence). There is no good evidence that NMP has the same benefits over SCS in terms of these clinically relevant outcomes. NMP does ...
Source: Cochrane Database of Systematic Reviews - September 12, 2023 Category: General Medicine Authors: Samuel J Tingle Joseph J Dobbins Emily R Thompson Rodrigo S Figueiredo Balaji Mahendran Sanjay Pandanaboyana Colin Wilson Source Type: research
Auxiliary Partial Orthotopic Liver Transplant as a Rescue Procedure for Acute Liver Failure with Extra-Small-for-Size Grafts: A Report of 2 Cases
We present 2 cases of acute liver failure treated with auxiliary partial orthotopic liver transplant using an extra-small-for-size graft. The first case was a 12-year-old female patient who presented with druginduced acute liver failure and required an auxiliary partial orthotopic liver transplant with an extra-small left lobe graft (graft-to-recipient weight ratio of 0.45). The second case was a 23-year-old male patient with acute liver failure of unknown etiology who underwent an auxiliary partial orthotopic liver transplant with a small right lobe graft (graft-torecipient weight ratio of 0.5). In both cases, computed to...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Amith Kumar Pakkala Gaurav Chaubal Aditya Nanavati Hunaid Hatimi Rajeev Sinha Ameet Mandot Uday Sanglodkar Alisha Chaubal Harshit Chaksota Samir Shah Source Type: research
Comparative Analysis of Donor Liver Allograft Outcomes in Hepatocellular Carcinoma Patients Who Underwent Liver Transplant
CONCLUSIONS: Similar outcomes can be achieved for hepatocellular carcinoma patients who undergo liver transplant with donations after brain death, donations after cardiac death, or donations after brain and cardiac death allografts, especially when strict donor selection criteria are applied.PMID:37698401 | DOI:10.6002/ect.2023.0119
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Abdulahad Abdulrab Mohammed Al-Ameri Zhisheng Zhou Shusen Zheng Source Type: research
Auxiliary Partial Orthotopic Liver Transplant as a Rescue Procedure for Acute Liver Failure with Extra-Small-for-Size Grafts: A Report of 2 Cases
We present 2 cases of acute liver failure treated with auxiliary partial orthotopic liver transplant using an extra-small-for-size graft. The first case was a 12-year-old female patient who presented with druginduced acute liver failure and required an auxiliary partial orthotopic liver transplant with an extra-small left lobe graft (graft-to-recipient weight ratio of 0.45). The second case was a 23-year-old male patient with acute liver failure of unknown etiology who underwent an auxiliary partial orthotopic liver transplant with a small right lobe graft (graft-torecipient weight ratio of 0.5). In both cases, computed to...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Amith Kumar Pakkala Gaurav Chaubal Aditya Nanavati Hunaid Hatimi Rajeev Sinha Ameet Mandot Uday Sanglodkar Alisha Chaubal Harshit Chaksota Samir Shah Source Type: research
Comparative Analysis of Donor Liver Allograft Outcomes in Hepatocellular Carcinoma Patients Who Underwent Liver Transplant
CONCLUSIONS: Similar outcomes can be achieved for hepatocellular carcinoma patients who undergo liver transplant with donations after brain death, donations after cardiac death, or donations after brain and cardiac death allografts, especially when strict donor selection criteria are applied.PMID:37698401 | DOI:10.6002/ect.2023.0119
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Abdulahad Abdulrab Mohammed Al-Ameri Zhisheng Zhou Shusen Zheng Source Type: research
Living Donor Liver Transplantation in Patients with Preformed Donor-Specific Anti-Human Leukocyte Antigen Antibodies Using Preoperative Desensitization Therapy According to Intensity of Donor-Specific Antibodies: A Single-Center Study
CONCLUSIONS Satisfactory LDLT results were achieved in DSA- and CREG-alone-positive cases following desensitization therapy.PMID:37697637 | DOI:10.12659/AOT.941346
Source: Annals of Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Kohei Ogawa Kei Tamura Katsunori Sakamoto Naotake Funamizu Masahiko Honjo Mikiya Shine Yusuke Nishi Tomoyuki Nagaoka Chihiro Ito Miku Iwata Mio Uraoka Yasutsugu Takada Source Type: research
Stimulator of interferon genes (STING): Key therapeutic targets in ischemia/reperfusion injury
Biomed Pharmacother. 2023 Sep 10;167:115458. doi: 10.1016/j.biopha.2023.115458. Online ahead of print.ABSTRACTThe Stimulator of Interferon Genes (STING) is predominantly expressed in immune cells, including macrophages, natural killer cells, dendritic cells, and T cells, functioning as a pattern recognition receptor. STING activation upon detecting cytosolic DNA released from damaged cells initiates downstream pathways, leading to the production of inflammatory cytokines such as IFNs, IL-6, and TNF-α. Dysregulated STING activation has been implicated in inflammatory and metabolic diseases. Ischemia/reperfusion injury (I/R...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 12, 2023 Category: Drugs & Pharmacology Authors: Juan Lv Xuanxuan Zhu Chunlei Xing Yuhong Chen Huihui Bian Heng Yin Xiaofeng Gu Li Su Source Type: research
