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Specialty: Neurology
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Total 80302 results found since Jan 2013.
Metacognition and sense of agency
Cognition. 2023 Sep 14;241:105622. doi: 10.1016/j.cognition.2023.105622. Online ahead of print.ABSTRACTIntelligent agents need to understand how they can change the world, and how they cannot change it, in order to make rational decisions for their forthcoming actions, and to adapt to their current environment. Previous research on the sense of agency, based largely on subjective ratings, failed to dissociate the sensitivity of sense of agency (i.e., the extent to which individual sense of agency tracks actual instrumental control over external events) from judgment criteria (i.e., the extent to which individuals self-attr...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Wen Wen Lucie Charles Patrick Haggard Source Type: research
The value of continuing research on epidemiology of cerebral palsy (CP) - What have we learned?
Eur J Paediatr Neurol. 2023 Sep 9:S1090-3798(23)00137-X. doi: 10.1016/j.ejpn.2023.09.004. Online ahead of print.NO ABSTRACTPMID:37716822 | DOI:10.1016/j.ejpn.2023.09.004
Source: European Journal of Paediatric Neurology - September 16, 2023 Category: Neurology Authors: Antigone S Papavasiliou Dimitrios Zafeiriou Source Type: research
Seizure-related stress and arousal responses mediate a relationship between anxiety trait and state in epilepsy
CONCLUSIONS: These findings elucidate the epilepsy-specific stress and arousal characteristics and their roles in mediating traits and state anxiety. These results may reflect the long-term clinical course and unique emotion recognition tendencies in epilepsy.PMID:37716325 | DOI:10.1016/j.yebeh.2023.109442
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Hironobu Nakamura Genichi Sugihara Keiko Hara Motoki Inaji Masahiro Noha Ichiro Takumi Masako Watanabe Hidehiko Takahashi Taketoshi Maehara Hitoshi Yamamoto Shunsuke Takagi Source Type: research
Prevalence and predictors of vitamin D deficiency among adults with epilepsy: A cross-sectional study
CONCLUSION: Vitamin D deficiency among PWE is prevalent in our local population, suggesting that regular screening should be considered for those at risk. Early identification would allow intervention to reduce the risk of future complications.PMID:37716324 | DOI:10.1016/j.yebeh.2023.109432
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ching Soong Khoo Mohd Fadzli Shukor Juen Kiem Tan Michelle Maryanne Tan Li Ling Yong Siti Zaleha Sahibulddin Siti Hajar Mat Desa Norasyikin A Wahab Rozita Hod Hui Jan Tan Source Type: research
Elevated CRP and TNF- α levels are associated with blunted neural oscillations serving fluid intelligence
DISCUSSION: Elevated inflammatory markers such as CRP and TNF-α were associated with aberrant neural oscillations in regions important for Gf. Linking inflammatory markers with regional neural oscillations may hold promise in identifying mechanisms of cognitive and psychiatric disorders.PMID:37716379 | DOI:10.1016/j.bbi.2023.09.012
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Sarah M Dietz Mikki Schantell Rachel K Spooner Megan E Sandal Amirsalar Mansouri Yasra Arif Hannah J Okelberry Jason A John Ryan Glesinger Pamela E May Elizabeth Heinrichs-Graham Adam J Case Matthew C Zimmerman Tony W Wilson Source Type: research
P2X < sub > 7 < /sub > R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
Brain Behav Immun. 2023 Sep 14:S0889-1591(23)00275-1. doi: 10.1016/j.bbi.2023.09.011. Online ahead of print.ABSTRACTThe purinoceptor P2X7R is a promising therapeutic target for tauopathies, including Alzheimer's disease (AD). Pharmacological inhibition or genetic knockdown of P2X7R ameliorates cognitive deficits and reduces pathological tau burden in mice that model aspects of tauopathy, including mice expressing mutant human frontotemporal dementia (FTD)-causing forms of tau. However, disagreements remain over which glial cell types express P2X7R and therefore the mechanism of action is unresolved. Here, we show that P2X7...
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Paula Beltran-Lobo Martina M Hughes Claire Troakes Cara L Croft Huzefa Rupawala Daniel Jutzi Marc-David Ruepp Maria Jimenez-Sanchez Michael S Perkinton Michael Kassiou Todd E Golde Diane P Hanger Alexei Verkhratsky Beatriz G Perez-Nievas Wendy Noble Source Type: research
Omega-3 polyunsaturated fatty acids and the psychiatric post-acute sequelae of COVID-19: A one-year retrospective cohort analysis of 33,908 patients
CONCLUSION: Omega-3 PUFAs may require re-evaluation as a preventive strategy against adverse mental health outcomes post-COVID-19 in placebo-controlled clinical trials.PMID:37716377 | DOI:10.1016/j.bbi.2023.09.008
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Ting-Hui Liu Chung-Han Ho Daniel Tzu-Li Chen Jheng-Yan Wu Po-Yu Huang Chih-Cheng Lai Kuang-Yang Hsieh Kuan-Pin Su Source Type: research
Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice
Behav Brain Res. 2023 Sep 15;455:114672. doi: 10.1016/j.bbr.2023.114672. Online ahead of print.ABSTRACTSevoflurane commonly adopted for anesthetic in clinical practice, however, its influences on cerebral blood flow and cognitive function remain controversial. Herein, the sevoflurane-induced hypotension on arterial blood pressure, cerebral blood flow, cognitive function, and hippocampal inflammation was investigated in mice. A significant decrease in arterial blood pressure and cerebral blood flow was indicated by the sevoflurane anesthesia treatment. Moreover, sevoflurane-induced hypotension was associated with the impair...
Source: Behavioural Brain Research - September 16, 2023 Category: Neurology Authors: Yuelian Luo Jiayi Liu Yu Hong Shuling Peng Shiyu Meng Source Type: research
Effect of auditory deprivation on adaptive locomotion: Interaction with lower visual field occlusion
This study aimed to investigate whether auditory deprivation affects adaptive locomotion. In particular, we aimed to elucidate the role of the auditory sense in obstacle avoidance by manipulating the visual field, which provides crucial sensory information for movement control. Sixteen participants approached a 15-cm obstacle located 6m away and stepped over it under four different conditions that combined two factors: the hearing condition controlled by wearing earmuffs with and without holes, and the lower visual field condition controlled by carrying opaque white and transparent boards. Spatiotemporal variables during t...
Source: Behavioural Brain Research - September 16, 2023 Category: Neurology Authors: Ryota Sakurai Yuka Miura Kentaro Kodama Masahiro Fujimoto Source Type: research
Nonlinear Neural Patterns Are Revealed In High Frequency Functional Near Infrared Spectroscopy Analysis
Brain Res Bull. 2023 Sep 14:110759. doi: 10.1016/j.brainresbull.2023.110759. Online ahead of print.ABSTRACTFunctional Near Infrared Spectroscopy (fNIRS) is a useful tool for measuring hemoglobin concentration. Linear theory of the hemodynamic response function supports low frequency analysis ( < 0.2 Hz). However, we hypothesized that nonlinearities, arising from the complex neurovascular interactions sustaining vasomotor tone, may be revealed in higher frequency components of fNIRS signals. To test this hypothesis, we simulated nonlinear hemodynamic models to explore how blood flow autoregulation changes may alter evoke...
Source: Brain Research Bulletin - September 16, 2023 Category: Neurology Authors: Ameer Ghouse Diego Candia Rivera Gaetano Valenza Source Type: research
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis
Exp Brain Res. 2023 Sep 16. doi: 10.1007/s00221-023-06702-w. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have been revealed to be involved in the pathology of acute ischemic stroke (AIS). Herein, we aimed to study the role and mechanism of circNCOA4 in ischemic stroke. The neuron-like cell line SK-N-SH of the experiment group was cultured in oxygen-glucose deprivation (OGD) condition. Cell viability and apoptosis were evaluated by cell counting kit-8 and flow cytometry. The oxidative damage and endoplasmic reticulum stress (ERS) were analyzed by measuring the production of reactive oxygen species (ROS), malondia...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Danyang Wang Sai Xiao Xiaoming Li Wenbo Qi Source Type: research
Sevoflurane-induced hypotension causes cognitive dysfunction and hippocampal inflammation in mice
Behav Brain Res. 2023 Sep 15;455:114672. doi: 10.1016/j.bbr.2023.114672. Online ahead of print.ABSTRACTSevoflurane commonly adopted for anesthetic in clinical practice, however, its influences on cerebral blood flow and cognitive function remain controversial. Herein, the sevoflurane-induced hypotension on arterial blood pressure, cerebral blood flow, cognitive function, and hippocampal inflammation was investigated in mice. A significant decrease in arterial blood pressure and cerebral blood flow was indicated by the sevoflurane anesthesia treatment. Moreover, sevoflurane-induced hypotension was associated with the impair...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Yuelian Luo Jiayi Liu Yu Hong Shuling Peng Shiyu Meng Source Type: research
Effect of auditory deprivation on adaptive locomotion: Interaction with lower visual field occlusion
This study aimed to investigate whether auditory deprivation affects adaptive locomotion. In particular, we aimed to elucidate the role of the auditory sense in obstacle avoidance by manipulating the visual field, which provides crucial sensory information for movement control. Sixteen participants approached a 15-cm obstacle located 6m away and stepped over it under four different conditions that combined two factors: the hearing condition controlled by wearing earmuffs with and without holes, and the lower visual field condition controlled by carrying opaque white and transparent boards. Spatiotemporal variables during t...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Ryota Sakurai Yuka Miura Kentaro Kodama Masahiro Fujimoto Source Type: research
Nonlinear Neural Patterns Are Revealed In High Frequency Functional Near Infrared Spectroscopy Analysis
Brain Res Bull. 2023 Sep 14:110759. doi: 10.1016/j.brainresbull.2023.110759. Online ahead of print.ABSTRACTFunctional Near Infrared Spectroscopy (fNIRS) is a useful tool for measuring hemoglobin concentration. Linear theory of the hemodynamic response function supports low frequency analysis ( < 0.2 Hz). However, we hypothesized that nonlinearities, arising from the complex neurovascular interactions sustaining vasomotor tone, may be revealed in higher frequency components of fNIRS signals. To test this hypothesis, we simulated nonlinear hemodynamic models to explore how blood flow autoregulation changes may alter evoke...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Ameer Ghouse Diego Candia Rivera Gaetano Valenza Source Type: research
Chronic memantine disrupts spatial memory and up-regulates Htr1a gene expression in the hippocampus of GPR39 (zinc-sensing receptor) KO male mice
We report: no effects of acute memantine on ELM; a tendency to improve the "where?" component of ELM in both WT and GPR39 KO mice following 12 days of memantine; and, a disruption of SM in GPR39KO mice after 24 days of memantine treatment. The latter result was associated with upregulation of Htr1a hippocampal expression.PMID:37716463 | DOI:10.1016/j.brainres.2023.148577
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Michal Rychlik Joanna Starnowska-Sokol Katarzyna Mlyniec Source Type: research
