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Phasic and tonic muscle synergies are different in number, structure and sparseness
This study aims at testing whether phasic and tonic components are generated by distinct phasic and tonic synergies or by the same set of synergies with phasic and tonic activation coefficients. The study also aims at characterizing the differences between the phasic and the tonic synergies. Using a comprehensive mapping of upper-limb point-to-point movements, synergies were extracted from phasic and tonic EMG signal separately, estimating the tonic components with a linear ramp model. The goodness of reconstruction (R2) as a function of the number of synergies was compared, and sets of synergies extracted from each datase...
Source: Human Movement Science - September 14, 2023 Category: Neurology Authors: Cristina Brambilla Marta Russo Andrea d'Avella Alessandro Scano Source Type: research

Signatures of task learning in neural representations
Curr Opin Neurobiol. 2023 Sep 12;83:102759. doi: 10.1016/j.conb.2023.102759. Online ahead of print.ABSTRACTWhile neural plasticity has long been studied as the basis of learning, the growth of large-scale neural recording techniques provides a unique opportunity to study how learning-induced activity changes are coordinated across neurons within the same circuit. These distributed changes can be understood through an evolution of the geometry of neural manifolds and latent dynamics underlying new computations. In parallel, studies of multi-task and continual learning in artificial neural networks hint at a tradeoff between...
Source: Current Opinion in Neurobiology - September 14, 2023 Category: Neurology Authors: Harsha Gurnani N Alex Cayco Gajic Source Type: research

Masked priming under the Bayesian microscope: Exploring the integration of local elements into global shape through Bayesian model comparison
Conscious Cogn. 2023 Sep 12;115:103568. doi: 10.1016/j.concog.2023.103568. Online ahead of print.ABSTRACTTo investigate whether local elements are grouped into global shapes in the absence of awareness, we introduced two different masked priming designs (e.g., the classic dissociation paradigm and a trial-wise probe and prime discrimination task) and collected both objective (i.e., performance based) and subjective (using the perceptual awareness scale [PAS]) awareness measures. Prime visibility was manipulated using three different prime-mask stimulus onset asynchronies (SOAs) and an unmasked condition. Our results showed...
Source: Consciousness and Cognition - September 14, 2023 Category: Neurology Authors: Mikel Jimenez Antonio Prieto Pablo G ómez Jos é Antonio Hinojosa Pedro R Montoro Source Type: research

Aphantasia within the framework of neurodivergence: Some preliminary data and the curse of the confidence gap
Conscious Cogn. 2023 Sep 12;115:103567. doi: 10.1016/j.concog.2023.103567. Online ahead of print.ABSTRACTAphantasia is a neurocognitive phenomenon affecting voluntary visual imagery, such that it is either entirely absent, or markedly impaired. Using both the social and medical models of disability, this article discusses the extent to which aphantasia can be understood as a disorder or just a form of neutral neurodivergence, given that imagery plays a central role in thinking and memory for most other people. Preliminary school performance data are presented, showing that low imagery does not necessarily complicate life, ...
Source: Consciousness and Cognition - September 14, 2023 Category: Neurology Authors: Merlin Monzel Carla Dance Elena Aza ñón Julia Simner Source Type: research

Masked priming under the Bayesian microscope: Exploring the integration of local elements into global shape through Bayesian model comparison
Conscious Cogn. 2023 Sep 12;115:103568. doi: 10.1016/j.concog.2023.103568. Online ahead of print.ABSTRACTTo investigate whether local elements are grouped into global shapes in the absence of awareness, we introduced two different masked priming designs (e.g., the classic dissociation paradigm and a trial-wise probe and prime discrimination task) and collected both objective (i.e., performance based) and subjective (using the perceptual awareness scale [PAS]) awareness measures. Prime visibility was manipulated using three different prime-mask stimulus onset asynchronies (SOAs) and an unmasked condition. Our results showed...
Source: Consciousness and Cognition - September 14, 2023 Category: Neurology Authors: Mikel Jimenez Antonio Prieto Pablo G ómez Jos é Antonio Hinojosa Pedro R Montoro Source Type: research

Aphantasia within the framework of neurodivergence: Some preliminary data and the curse of the confidence gap
Conscious Cogn. 2023 Sep 12;115:103567. doi: 10.1016/j.concog.2023.103567. Online ahead of print.ABSTRACTAphantasia is a neurocognitive phenomenon affecting voluntary visual imagery, such that it is either entirely absent, or markedly impaired. Using both the social and medical models of disability, this article discusses the extent to which aphantasia can be understood as a disorder or just a form of neutral neurodivergence, given that imagery plays a central role in thinking and memory for most other people. Preliminary school performance data are presented, showing that low imagery does not necessarily complicate life, ...
Source: Consciousness and Cognition - September 14, 2023 Category: Neurology Authors: Merlin Monzel Carla Dance Elena Aza ñón Julia Simner Source Type: research

Lumateperone Monotherapy for Treatment-Resistant OCD in an Adolescent
CNS Spectr. 2023 Sep 14:1-6. doi: 10.1017/S1092852923002468. Online ahead of print.NO ABSTRACTPMID:37706369 | DOI:10.1017/S1092852923002468
Source: CNS Spectrums - September 14, 2023 Category: Neurology Authors: Ahmed Naguy Saxby Pridmore Mohamed Y Abuzeid Dalal Elsori Bibi Alamiri Source Type: research

Artificial intelligence is set to transform mental health services
CNS Spectr. 2023 Sep 14:1-7. doi: 10.1017/S1092852923002456. Online ahead of print.NO ABSTRACTPMID:37706366 | DOI:10.1017/S1092852923002456
Source: CNS Spectrums - September 14, 2023 Category: Neurology Authors: Seithikurippu R Pandi-Perumal Meera Narasimhan Mary V Seeman Haitham Jahrami Source Type: research

Response to 'Neurologists should retain diagnostic and therapeutic management of migraines'
Neurol Neurochir Pol. 2023 Sep 14. doi: 10.5603/pjnns.97421. Online ahead of print.NO ABSTRACTPMID:37706669 | DOI:10.5603/pjnns.97421
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Magdalena Boczarska-Jedynak Source Type: research

Differences in diffusion tensor imaging parameters of brain white matter tracts between patients with myotonic dystrophy type 1 and type 2 - a retrospective single-centre study
CONCLUSIONS: Our results indicate diffuse disintegration of white matter pathways in DM patients, especially in the DM1 group. The damage to all types of fibres (association, commissural, and projection) may explain the diversity of clinical symptoms, which were more severe in the DM1 group of patients than in the DM2 group.CLINICAL IMPLICATIONS: DTI in patients with DM may help us to understand the neural mechanisms underlying brain involvement during the disease. In future, it may help to identify biomarkers for disease progression and treatment response.PMID:37706668 | DOI:10.5603/pjnns.95587
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Edyta Maj Tomasz Wolak Joanna de Meulder Katarzyna Janiszewska Miko łaj Wojtaszek Anna Kostera-Pruszczyk Marek Go łębiowski Anna Łusakowska Source Type: research

Signatures of task learning in neural representations
Curr Opin Neurobiol. 2023 Sep 12;83:102759. doi: 10.1016/j.conb.2023.102759. Online ahead of print.ABSTRACTWhile neural plasticity has long been studied as the basis of learning, the growth of large-scale neural recording techniques provides a unique opportunity to study how learning-induced activity changes are coordinated across neurons within the same circuit. These distributed changes can be understood through an evolution of the geometry of neural manifolds and latent dynamics underlying new computations. In parallel, studies of multi-task and continual learning in artificial neural networks hint at a tradeoff between...
Source: Current Opinion in Neurobiology - September 14, 2023 Category: Neurology Authors: Harsha Gurnani N Alex Cayco Gajic Source Type: research

Neurologists should retain diagnostic and therapeutic management of migraines
Neurol Neurochir Pol. 2023 Sep 14. doi: 10.5603/pjnns.96686. Online ahead of print.NO ABSTRACTPMID:37706667 | DOI:10.5603/pjnns.96686
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Josef Finsterer Source Type: research

Phasic and tonic muscle synergies are different in number, structure and sparseness
This study aims at testing whether phasic and tonic components are generated by distinct phasic and tonic synergies or by the same set of synergies with phasic and tonic activation coefficients. The study also aims at characterizing the differences between the phasic and the tonic synergies. Using a comprehensive mapping of upper-limb point-to-point movements, synergies were extracted from phasic and tonic EMG signal separately, estimating the tonic components with a linear ramp model. The goodness of reconstruction (R2) as a function of the number of synergies was compared, and sets of synergies extracted from each datase...
Source: Human Movement Science - September 14, 2023 Category: Neurology Authors: Cristina Brambilla Marta Russo Andrea d'Avella Alessandro Scano Source Type: research

Response to 'Neurologists should retain diagnostic and therapeutic management of migraines'
Neurol Neurochir Pol. 2023 Sep 14. doi: 10.5603/pjnns.97421. Online ahead of print.NO ABSTRACTPMID:37706669 | DOI:10.5603/pjnns.97421
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Magdalena Boczarska-Jedynak Source Type: research