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Total 1589675 results found since Jan 2013.

Aggressive variant prostate cancer: A case report and literature review
CONCLUSION: We should reach consensus definitions of the AVPC and other androgen receptor-independent subtypes of PCA and develop new biomarkers to identify groups of high-risk variants. It is crucial to complete a puncture biopsy of the tumor or metastatic lesion as soon as possible in patients with advanced PCA who exhibit clinical features such as low Prostate-specific antigen levels, high carcinoembryonic antigen levels, and insensitivity to hormones to determine the pathological histological type and to create a more aggressive monitoring and treatment regimens.PMID:37731555 | PMC:PMC10507546 | DOI:10.12998/wjcc.v11.i26.6213
Source: Clinical Prostate Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Xiang-Tao Weng Wen-Li Lin Qi-Man Pan Tao-Fen Chen Si-Yi Li Chi-Ming Gu Source Type: research

Artificial intelligence for telemedicine diabetic retinopathy screening: a review
CONCLUSIONS: Telemedicine and AI hold great promise for augmenting decision-making in medical care, expanding patient access and enhancing cost-effectiveness. Economic studies and social science analysis are crucial to support the implementation of AI in teleophthalmology screening programs. Promoting fairness and generalizability in automated systems combined with telemedicine screening programs is not straightforward. Improving data representativeness, reducing biases and promoting equity in deployment and post-deployment studies are all critical steps in model development.PMID:37734417 | DOI:10.1080/07853890.2023.2258149
Source: Annals of Medicine - September 21, 2023 Category: Internal Medicine Authors: Luis Filipe Nakayama Lucas Zago Ribeiro Frederico Novaes Isabele Ayumi Miyawaki Andresa Emy Miyawaki Juliana Ang élica Estevão de Oliveira Talita Oliveira Fernando Korn Malerbi Caio Vinicius Saito Regatieri Leo Anthony Celi Paolo S Silva Source Type: research

Development of a nomogram for the prediction of acute kidney injury after liver transplantation: a model based on clinical parameters and postoperative cystatin C level
CONCLUSION: The model based on combinations of clinical parameters and postoperative cystatin C levels had a higher predictive performance for post-LT AKI than the model based on clinical parameters or postoperative cystatin C level alone. Additionally, we developed an easy-to-use nomogram based on the final model, which could aid in the early detection of AKI and improve the prognosis of patients after LT.PMID:37734410 | DOI:10.1080/07853890.2023.2259410
Source: Annals of Medicine - September 21, 2023 Category: Internal Medicine Authors: Zhipeng Wu Yi Wang Li He Boxun Jin Qinwei Yao Guangming Li Xin Wang Yingmin Ma Source Type: research

Comparison of binocular visual quality in six treatment protocols for bilateral cataract surgery with presbyopia correction: a prospective two-center single-blinded cohort study
CONCLUSIONS: The trifocal protocol showed the best performance, and the monovision protocol presented the worst performance in most perspectives of binocular visual quality for presbyopia correction. The refractive bifocal, mixed, or EROV protocols can provide an approximate performance as a trifocal protocol. Ophthalmologists can customize therapies using different protocols.PMID:37734409 | DOI:10.1080/07853890.2023.2258894
Source: Annals of Medicine - September 21, 2023 Category: Internal Medicine Authors: Qianqian Lan Fan Xu Tong Sun Siming Zeng Yiyun Liu Tingting Yang Yaxin Li Gang Yao Baikai Ma Liyuan Tao Boping Ma Xin Xiao Min Li Hong Qi Source Type: research

Association between COVID-19 and sexual health: an umbrella review
CONCLUSION: Our findings highlight the importance of sexual health among COVID-19 patients and people affected due to COVID-19. Further critical studies should investigate the mechanism underlying the association between COVID-19 and sexual health.PMID:37733015 | DOI:10.1080/07853890.2023.2258902
Source: Annals of Medicine - September 21, 2023 Category: Internal Medicine Authors: Wen-Yi Liu Zhu Liduzi Jiesisibieke Ching-Wen Chien Tao-Hsin Tung Source Type: research

Management of eyelids' primary malignancies
Conclusion: The anatomical and functional features of the eyelids require a good reconstruction of the transfixion eyelid defect. Many reconstruction methods are available, allowing extensive and complex palpebral repairs. Oncologic prognosis is conditioned by the surgical quality.PMID:37731362 | DOI:10.1080/19932820.2023.2258668
Source: Libyan Journal of Medicine - September 21, 2023 Category: General Medicine Authors: Hsouna Zgolli Racem Choura Hamad K H Elzarrug Chiraz Abdelhedi Amel Chebbi Source Type: research

Prediction of cytology-histology discrepancy when Bethesda cytology reports benign results for thyroid nodules in women: with special emphasis on pregnancy
Conclusions: Risk of malignancy in a presumably benign thyroid disease should not be ignored. Radiology-cytology correlation by an experienced dedicated team may help in decreasing sampling errors. Physiologic changes caused by pregnancy may shade malignant transformation in thyrocytes, and it would be appropriate to be cautious about benign FNA taken during this period.PMID:37731357 | DOI:10.1080/19932820.2023.2258670
Source: Libyan Journal of Medicine - September 21, 2023 Category: General Medicine Authors: Aysun Firat Ethem Unal Source Type: research

Patient-doctor interactions around alternative and complementary medicine in the context of oncology care in a Latin American country
CONCLUSIONS: The low frequency of communication contrasts to the increasing use of CAM. Divergent perspectives between doctors and patients could limit shared decision-making on the use of CAM. Enhanced knowledge and education on CAM for both actors is fundamental to improve their interaction and to move away from paternalistic and confrontational communication, particularly in a world region with cultural backgrounds that influence the use of CAM.PMID:37734425 | DOI:10.1016/j.ctim.2023.102986
Source: Complementary Therapies in Medicine - September 21, 2023 Category: Complementary Medicine Authors: Pilar Garc ía-Padilla Dennys Garc ía-Padilla Maria Fernanda Ram írez-Castro Paula Pulido-Rinc ón Ra úl Murillo Source Type: research

Research Progress and New Perspectives of Anticancer Effects of Emodin
In conclusion, emodin represents a promising natural compound with potent anticancer properties, and its potential as a therapeutic agent for cancer treatment warrants further investigation. This review provides a comprehensive overview of the current research progress and new perspectives on emodin's anticancer effects, which may facilitate the development of novel therapeutic strategies for cancer treatment.PMID:37732372 | DOI:10.1142/S0192415X23500787
Source: The American Journal of Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Wu Liu Eskandar Qaed Yuelin Zhu Wenzhang Tian Yizhen Wang Le Kang Xiaodong Ma Zeyao Tang Source Type: research

Understanding Head Injury Risks During Car-to-Pedestrian Collisions Using Realistic Vehicle and Detailed Human Body Models
Stapp Car Crash J. 2022 Nov;66:175-205. doi: 10.4271/2022-22-0006.ABSTRACTTraumatic brain injury (TBI) is the leading cause of death and long-term disability in road traffic accidents (RTAs). Researchers have examined the effect of vehicle front shape and pedestrian body size on the risk of pedestrian head injury. On the other hand, the relationship between vehicle front shape parameters and pedestrian TBI risks involving a diverse population with varying body sizes has yet to be investigated. Thus, the purpose of this study was to comprehensively study the effect of vehicle front shape parameters and various pedestrian bo...
Source: Stapp Car Crash Journal - September 21, 2023 Category: Accident Prevention Authors: Kalish Gunasekaran Sakib Ul Islam Haojie Mao Source Type: research

Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: Methods of Information in Medicine - September 21, 2023 Category: Information Technology Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research

Immunohistochemical expression of NRF2 is correlated with the magnitude of inflammation and fibrosis in chronic liver disease
ConclusionsNuclear translocation of NRF2 was correlated with the magnitude of liver inflammation and fibrosis in chronic liver disease. These results suggest that NRF2 plays a protective role in the development of chronic liver diseases such as NASH and CHc.
Source: Cancer Medicine - September 21, 2023 Category: Cancer & Oncology Authors: Keii To, Kosuke Okada, Takahisa Watahiki, Hideo Suzuki, Kiichiro Tsuchiya, Katsutoshi Tokushige, Masakazu Yamamoto, Shun ‐ichi Ariizumi, Junichi Shoda Tags: RESEARCH ARTICLE Source Type: research

How should extra ‐large Lugol‐unstained lesions of the esophagus be treated? Results from a population‐based cohort study
ConclusionsResults from this study suggest physician –patient shared decision-making regarding clinical treatment or intensive surveillance should be carried out for LULs>20  mm in the esophagus, regardless of the histologic diagnosis. For those with LULs of 16–20 mm, intensive surveillance would also best be considered.
Source: Cancer Medicine - September 21, 2023 Category: Cancer & Oncology Authors: Mengfei Liu, Zifan Qi, Ren Zhou, Chuanhai Guo, Anxiang Liu, Haijun Yang, Fenglei Li, Liping Duan, Lin Shen, Qi Wu, Zhen Liu, Yaqi Pan, Fangfang Liu, Ying Liu, Hong Cai, Zhonghu He, Yang Ke Tags: RESEARCH ARTICLE Source Type: research

The 2024 Jaguar F-Type is a traditional sports car in all the right ways
With a supercharged V8 under the hood and modern amenities in the cabin, the 2024 Jaguar F-Type is a modern interpretation of a traditional luxury sports car. Pricing starts at $77,900. As a faithful spiritual successor to the iconic E-Type, the Jaguar F-Type is old-school in all the right ways.…#v8 #jaguarftype
Source: Reuters: Health - September 21, 2023 Category: Consumer Health News Source Type: news

Perspectives for immunotherapy of EBV ‐associated GLELC: A relatively “hot” tumor microenvironment
ConclusionCompared with GAC, EBVaGLELC revealed higher T cell infiltration and less intense of angiogenesis. It displays relatively “hot” TME that may provide the rationality to treat with immunotherapy in EBV-related GLELC.
Source: Cancer Medicine - September 21, 2023 Category: Cancer & Oncology Authors: Yanna Lei, Peng Cao, Xiufeng Zheng, Jing Wei, Mo Cheng, Ming Liu Tags: RESEARCH ARTICLE Source Type: research