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In reply to the Letter to the Editor regarding: Identifying large vessel occlusion using the hyperdense artery sign in patients treated with mechanical thrombectomy
We sincerely thank Drs. Shunji Mugikura and Naoko Mori for the interest and comments in our article, “Identifying large vessel occlusion using the hyperdense artery sign in patients treated with mechanical thrombectomy”.1
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Takuya Saito, Ryo Itabashi, Kazutaka Uchida, Yuichi Kawabata, Shota Igasaki, Kazuhiko Sato, Tomohiro Chiba, Takeshi Morimoto, Yukako Yazawa Tags: Letter to the Editor Source Type: research

Before juvenile stroke can be attributed to MYH11 variants, alternative etiologies and pathophysiologies must be adequately ruled out
We read with interest the article by Raghuram et  al. on a 12 year-old female who developed severe ischemic stroke (NIHSS 16) due to right proximal middle cerebral artery (MCA) occlusion [1]. Despite thrombolysis and thrombectomy, the patient's recovery was incomplete [1]. The cause of the occlusion was attributed to a focal dissection of the MCA due to the variant IVS32G>A in MYH11, which was also found in the maternal grandmother, mother, older sister, and a maternal cousin, two of whom had aortic dissection in the past [1].
Source: Journal of Stroke and Cerebrovascular Diseases - September 20, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

Renal Dysfunction Among Stroke Patients, Hospital Based Cross Sectional Study, Addis Ababa, Ethiopia, 2021
Conclusion: Renal  dysfunction is a frequent comorbidity in patients who are admitted with the diagnosis of acute stroke and had a higher mortality rate  than stroke patients with normal renal function. 
Source: Ethiopian Journal of Health Development - September 20, 2023 Category: African Health Authors: Lissane Seifu, Yonas Gashaye, Melaku Taye Source Type: research

Combined coronary and carotid artery disease: what to operate on first? or both at the same time?
Heart disease and stroke rank amongst the top four leading causes of death in the United States.1 Studies have demonstrated a positive correlation between the two, even suggesting that carotid artery disease may predict the presence of coronary artery disease (CAD).2,3 In fact, some have found that the prevalence of carotid artery stenosis (CAS) in those undergoing coronary artery bypass grafting (CABG) may be as high as 8-14%.4 Despite such co-existence, there remains no clear consensus Guidelines for revascularization in patients with co-existing CAD and CAS.
Source: Journal of Cardiothoracic and Vascular Anesthesia - September 20, 2023 Category: Anesthesiology Authors: Sherman Yu, Mark A. Chaney Tags: Case Conference Source Type: research

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

FXI Inhibitor Cuts Bleeds in Afib; COAPT Extends to Real World; AI Stroke Triage
(MedPage Today) -- People who were prone to needing dentures tended to also be at higher risk of cardiometabolic disease. (European Journal of Preventive Cardiology) Early real-world experience at a Dutch lipid clinic suggests smaller LDL cholesterol...
Source: MedPage Today Cardiovascular - September 19, 2023 Category: Cardiology Source Type: news

De-escalation from ticagrelor to clopidogrel in patients with acute myocardial infarction: the TALOS-AMI HBR substudy
CONCLUSIONS: In stabilised acute myocardial infarction patients, unguided de-escalation from ticagrelor to clopidogrel was associated with a lower rate of net adverse clinical outcomes irrespective of HBR status. The effect of de-escalation of P2Y12 inhibition on reducing haemorrhagic events was greater in patients with HBR.PMID:37724337 | DOI:10.4244/EIJ-D-23-00427
Source: EuroIntervention - September 19, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Min Chul Kim Sung Gyun Ahn Kyung Hoon Cho Doo Sun Sim Young Joon Hong Ju Han Kim Myung Ho Jeong Jun-Won Lee Young-Jin Youn Hee-Yeol Kim Ki-Dong Yoo Doo-Soo Jeon Eun-Seok Shin Young-Hoon Jeong Kiyuk Chang Youngkeun Ahn Source Type: research

A comparison of chronic conditions and health characteristics between cancer survivors and non-cancer survivors
DISCUSSION: These findings can be used by healthcare and public health practitioners to evaluate the programmatic efforts and resources, implement targeted interventions toward cancer survivors, and improve health and quality of life.PMID:37724026 | DOI:10.1177/17423953231180191
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Anjin Singh Michael Shayne Gallaway Addey Rascon Source Type: research

Feasibility of using the Cognitive Orientation to daily Occupational Performance in a population of Danish stroke survivors: Adaptation and study protocol
CONCLUSIONS AND SIGNIFICANCE: The planned feasibility study will contribute to further developing and refining the intervention before performing a possible large-scale effectiveness study.PMID:37726001 | DOI:10.1080/11038128.2023.2258202
Source: Scandinavian Journal of Occupational Therapy - September 19, 2023 Category: Occupational Health Authors: Louise Moeldrup Nielsen Helene Polatajko Mette Brandi Tove Lise Nielsen Source Type: research

Measurement properties of performance-based instruments for assessing mental function during activity and participation in persons with stroke: A systematic review
CONCLUSIONS: Further studies of high methodological quality are needed that evaluate the measurement properties of instruments to allow clinicians and researchers to select the most suitable performance-based measures for purpose.SIGNIFICANCE: Results may be used to select the most suitable performance-based instrument to measure mental function during activity and participation in persons with stroke.TRIAL REGISTRATION NUMBER: PROSPERO CRD42018086744.PMID:37725997 | DOI:10.1080/11038128.2023.2258161
Source: Scandinavian Journal of Occupational Therapy - September 19, 2023 Category: Occupational Health Authors: Lola Qvist Kristensen Maurits W van Tulder Frederik Rosenb æk Marie Almkvist Muren Hanne Kaae Kristensen Lidwine B Mokkink Lisa Gregersen Oestergaard Source Type: research

The hemodynamic interplay between pulmonary ischemia-reperfusion injury and right ventricular function in lung transplantation: A translational porcine model
In conclusion, we demonstrate a delicate balance between development of pulmonary ischemia-reperfusion injury and right ventricular function during lung transplantation. Furthermore, we provide a physiological basis for potential benefit of extracorporeal life support technology.PMID:37724349 | DOI:10.1152/ajplung.00281.2022
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 19, 2023 Category: Cytology Authors: Michaela Orlitov á Tom Verbelen Anna E Frick Arno Vanstapel Dieter Van Beersel Sofie Ordies Jan Van Slambrouck Janne Kaes Jin Xin Walter Coudyzer Stijn E Verleden Geert M Verleden Bart M Vanaudenaerde Dirk E Van Raemdonck Robin Vos Laurens J Ceulemans Pi Source Type: research

Regional differences in the utilization and outcomes of cerebral embolic protection during transcatheter aortic valve replacement: an analysis of the National Inpatient Sample from 2017 through 2019
Conclusion: Within the USA, there are regional differences in the utilization and outcomes of CEP use during TAVR. To prevent regional disparities and ensure consistent quality of care in the USA, further research is needed to determine what variable(s) may be responsible for regional differences in TAVR outcomes, with or without CEP.PMID:37724712 | DOI:10.57264/cer-2023-0010
Source: Journal of Comparative Effectiveness Research - September 19, 2023 Category: General Medicine Authors: Elisa M Amoroso Source Type: research

Long-term outcomes after conservative and EDAS treatment for 111 elderly patients with moyamoya disease: longitudinal and cross-sectional study
CONCLUSIONS: The postoperative long-term stroke rate among elderly patients with MMD was lower in the EDAS group than in the conservative treatment group. Long-term stroke events were associated with advanced age, aneurysm, and initial ischemia after conservative treatment and only initial hemorrhage after EDAS.PMID:37724788 | DOI:10.3171/2023.7.JNS231060
Source: Journal of Neurosurgery - September 19, 2023 Category: Neurosurgery Authors: Jing-Jie Li Xiao-Peng Wang Qian-Nan Wang Xiang-Yang Bao Qing-Bao Guo Zi-Qing Kong Gan Gao Min-Jie Wang Si-Meng Liu He-Guan Fu Qian Zhang Lian Duan Source Type: research

Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research

First-Ever Ischemic Stroke In Covid-19: How Is It Different? - A Stroke Registry-Based Study From South India
Acta Neurol Taiwan. 2023 Dec 30;32(4):190-201.ABSTRACTStroke associated with COVID-19 has been characterised in several multicentre retrospective studies and meta-analyses. However, they did not distinguish first-ever ischemic strokes (F-AIS). Therefore, we aimed to study the incidence, clinical characteristics, and outcomes of a cohort of F-AIS associated with COVID-19 during the first wave of the pandemic and compare this cohort with those of F-AIS without COVID-19, COVID-19 without stroke. We also sought to compare the stroke admissions and mechanisms during the pandemic and immediate prepandemic periods.PMID:37723911
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Muralidhar Reddy Y Jagarlapudi Mk Murthy Sreekanth Reddy Y Abhinay Kumar Gattu Shyam K Jaiswal Lalitha Pidaparthi Subhendu Parida Santhosh Kumar B Syed Osman Shanti Naidu Kamatam Source Type: research