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Total 4677907 results found since Jan 2013.

Phase II Trial of the Sigma-1 Receptor Agonist Cutamesine (SA4503) for Recovery Enhancement After Acute Ischemic Stroke Clinical Sciences
Conclusions— Cutamesine was safe and well tolerated at both dosage levels. Although no significant effects on functional end points were seen in the population as a whole, greater improvement in National Institutes of Health Stroke Scale scores among patients with greater pretreatment deficits seen in post hoc analysis warrants further investigation. Additional studies should focus on the patient population with moderate-to-severe stroke. Clinical Trial Registration— URL: http://www.clinicaltrials.gov/show/NCT00639249. Unique identifier: NCT00639249. The EudraCT number is 2007-004840-60 (https://www.clinicaltr...
Source: Stroke - October 27, 2014 Category: Neurology Authors: Urfer, R., Moebius, H. J., Skoloudik, D., Santamarina, E., Sato, W., Mita, S., Muir, K. W., for the Cutamesine Stroke Recovery Study Group Tags: Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Stroke Unit Care Benefits Patients With Intracerebral Hemorrhage: Systematic Review and Meta-analysis Clinical Sciences
Conclusions— Patients with intracerebral hemorrhage seem to benefit at least as much as patients with ischemic stroke from organized inpatient (stroke unit) care.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Langhorne, P., Fearon, P., Ronning, O. M., Kaste, M., Palomaki, H., Vemmos, K., Kalra, L., Indredavik, B., Blomstrand, C., Rodgers, H., Dennis, M. S., Salman, R. A.-S., on behalf of the Stroke Unit Trialists' Collaboration, The following collaborators pro Tags: Other Treatment, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Atrial Fibrillation in Ischemic Stroke: Predicting Response to Thrombolysis and Clinical Outcomes Original Contributions
Conclusions— Stroke patients with AF have higher mortality, greater risk of intracerebral hemorrhage, and a similar response trend to thrombolysis compared with non-AF patients.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Saposnik, G., Gladstone, D., Raptis, R., Zhou, L., Hart, R. G., on behalf of the Investigators of the Registry of the Canadian Stroke Network (RCSN) and the Stroke Outcomes Research Canada (SORCan) Working Group Tags: Acute Cerebral Infarction, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research

Effects of Candesartan in Acute Stroke on Cognitive Function and Quality of Life: Results From the Scandinavian Candesartan Acute Stroke Trial Brief Reports
Conclusions— Candesartan did not improve cognitive function or quality of life. Rather, there were signs of harmful effects. These findings support the conclusion from our previous report that there is no indication for routine blood pressure–lowering treatment with candesartan in the acute phase of stroke. Clinical Trial Registration— URL: www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Hornslien, A. G., Sandset, E. C., Bath, P. M., Wyller, T. B., Berge, E., on Behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cardiovascular Pharmacology, Cerebrovascular disease/stroke, Acute Stroke Syndromes, Other Stroke Treatment - Medical Brief Reports Source Type: research

Factors Associated With 28-Day Hospital Readmission After Stroke in Australia Clinical Sciences
Conclusions— This is the first study to comprehensively evaluate factors associated with 28-day readmission after stroke. The factors associated with 28-day readmission are diverse and include potentially modifiable and nonmodifiable factors.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Kilkenny, M. F., Longworth, M., Pollack, M., Levi, C., Cadilhac, D. A., on behalf of New South Wales Stroke Services Coordinating Committee and the Agency for Clinical Innovation Tags: Health policy and outcome research, Cerebrovascular disease/stroke, Other Stroke Clinical Sciences Source Type: research

Review, Historical Context, and Clarifications of the NINDS rt-PA Stroke Trials Exclusion Criteria: Part 1: Rapidly Improving Stroke Symptoms Clinical Sciences
Conclusions— A structured framework and quantitative approach toward defining RISS emerged through expert opinion and consensus. The term, RISS, should be reserved for those who improve to a mild deficit, specifically one which is perceived to be nondisabling. This is recommended to guide decision making on intravenous tPA eligibility going forward, including the design of future studies. An additional study of patients with rapid improvement to nonmild deficits is not justified because these patients should be treated.
Source: Stroke - August 26, 2013 Category: Neurology Authors: The Re-examining Acute Eligibility for Thrombolysis (TREAT) Task Force:, Levine, S. R., Khatri, P., Broderick, J. P., Grotta, J. C., Kasner, S. E., Kim, D., Meyer, B. C., Panagos, P., Romano, J., Scott, P., NINDS rt-PA Stroke Trial Investigators* Tags: Acute Cerebral Infarction, Acute Stroke Syndromes, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Very Low Quality of Life After Acute Stroke: Data From the Efficacy of Nitric Oxide in Stroke Trial Clinical Sciences
Conclusions— Very low health-related quality of life is relatively common after stroke, particularly in patients with mobility problems or who are dependent on help for usual activities, and is related to poor functional outcome measures. Clinical Trial Registration— URL: http://www.controlled-trials.com/. Unique identifier: ISRCTN99414122.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Sprigg, N., Selby, J., Fox, L., Berge, E., Whynes, D., Bath, P. M. W., for the Efficacy of Nitric Oxide in Stroke Investigators Tags: Other Stroke Clinical Sciences Source Type: research

Australian Public's Awareness of Stroke Warning Signs Improves After National Multimedia Campaigns Brief Reports
Conclusions— The Australian public’s awareness of stroke warning signs has improved since commencement of the NSF campaigns commensurate with greater awareness of stroke advertising. Public education efforts are worthwhile, and future efforts should focus on groups identified with low awareness or those at high risk of stroke.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Bray, J. E., Johnson, R., Trobbiani, K., Mosley, I., Lalor, E., Cadilhac, D., on behalf of the National Stroke Foundation Tags: Acute Stroke Syndromes Brief Reports Source Type: research

Urgent Carotid Surgery and Stenting May Be Safe After Systemic Thrombolysis for Stroke Clinical Sciences
Conclusions— Urgent carotid endarterectomy or carotid artery stenting after thrombolysis for stroke may be safe without increased risk of serious complications.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Koraen-Smith, L., Troeng, T., Bjorck, M., Kragsterman, B., Wahlgren, C.-M., on behalf of the Swedish Vascular Registry and the Riks-Stroke Collaboration, This work was supported by the Steering Committee of the Swedish Vascular Registry (Swedvasc):, Krags Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

Impaired Glucose Regulation Predicted 1-Year Mortality of Chinese Patients With Ischemic Stroke: Data From Abnormal Glucose Regulation in Patients With Acute Stroke Across China Brief Reports
Conclusions— IGR was an independent predictor for the mortality of patients with ischemic stroke. IGR should be highlighted and intervened actively in the patients with ischemic stroke.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Jia, Q., Liu, G., Zheng, H., Zhao, X., Wang, C., Wang, Y., Liu, L., Wang, Y., on behalf of the Investigators for the Survey on Abnormal Glucose Regulation in Patients With Acute Stroke Across China Tags: Cerebrovascular disease/stroke, Glucose intolerance, Risk Factors for Stroke Brief Reports Source Type: research

Geomagnetic Storms Can Trigger Stroke: Evidence From 6 Large Population-Based Studies in Europe and Australasia Clinical Sciences
Conclusions— Geomagnetic storms are associated with increased risk of stroke and should be considered along with other established risk factors. Our findings provide a framework to advance stroke prevention through future investigation of the contribution of geomagnetic factors to the risk of stroke occurrence and pathogenesis.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Feigin, V. L., Parmar, P. G., Barker-Collo, S., Bennett, D. A., Anderson, C. S., Thrift, A. G., Stegmayr, B., Rothwell, P. M., Giroud, M., Bejot, Y., Carvil, P., Krishnamurthi, R., Kasabov, N., for the International Stroke Incidence Studies Data Pooling P Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Effects of Stroke Education of Junior High School Students on Stroke Knowledge of Their Parents: Tochigi Project Brief Reports
Conclusions— Improvement of stroke knowledge immediately after the stroke lesson was observed in parents as well as their children, which indicated that our teaching materials using the Manga was effective in delivering the stroke knowledge to parents through their children.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Matsuzono, K., Yokota, C., Takekawa, H., Okamura, T., Miyamatsu, N., Nakayama, H., Nishimura, K., Ohyama, S., Ishigami, A., Okumura, K., Toyoda, K., Miyamoto, Y., Minematsu, K., on behalf of the Tochigi Junior High School Stroke Education Group, Participa Tags: Behavioral Changes and Stroke Brief Reports Source Type: research

Implementing a Simple Care Bundle Is Associated With Improved Outcomes in a National Cohort of Patients With Ischemic Stroke Clinical Sciences
Conclusions— Achieving a care bundle for ischemic stroke is associated with reduced mortality at 30 days and 6 months and increased likelihood of discharge to usual residence at 6 months.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Turner, M., Barber, M., Dodds, H., Murphy, D., Dennis, M., Langhorne, P., Macleod, M.-J., on behalf of the Scottish Stroke Care Audit Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Mechanical Thrombectomy in and Outside the REVASCAT Trial: Insights From a Concurrent Population-Based Stroke Registry Clinical Sciences
Conclusions— REVASCAT enrolled nearly all eligible patients representing one third of all patients treated with EVT. Patients treated with EVT within and outside REVASCAT had similar outcomes, reinforcing the therapeutic value of EVT. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01692379.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Urra, X., Abilleira, S., Dorado, L., Ribo, M., Cardona, P., Millan, M., Chamorro, A., Molina, C., Cobo, E., Davalos, A., Jovin, T. G., Gallofre, M., Catalan Stroke Code and Reperfusion Consortium, Catalan Stroke Code and Reperfusion Consortium Stroke Prog Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research