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Total 293778 results found since Jan 2013.

Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants
CONCLUSIONS: The ENDS usage appears to be associated with a higher risk of stroke compared to non-use, whereas there was no association between former ENDS use and the risk of stroke.PMID:37732043 | PMC:PMC10507757 | DOI:10.5114/aoms/171473
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Kamal Awad Maged Mohammed Seth S Martin Maciej Banach Source Type: research

The effects of cycling on walking outcomes in adults with stroke: a systematic review
CONCLUSION: Considerable heterogeneity was observed across cycling protocols with respect to intensity, frequency, exercise duration and protocol duration. However, none of the studies reported declines in walking outcomes and improvements were measured in the absence of task-specific gait training. Cycling interventions employing moderate- to high-intensity aerobic training and 24 sessions or more may be optimal in improving gait velocity and walking capacity.PMID:37732513 | DOI:10.1080/10749357.2023.2259167
Source: Topics in Stroke Rehabilitation - September 21, 2023 Category: Neurology Authors: Madeeha Khan Logan M Maag Mary Pat Harnegie Susan M Linder Source Type: research

Oral Anticoagulation Use and Left Atrial Appendage Occlusion in LAAOS III
CONCLUSIONS: The benefit of LAA occlusion was consistent whether patients were receiving OACs or not. LAA occlusion provides thromboembolism reduction in patients independent of OAC use.PMID:37732457 | DOI:10.1161/CIRCULATIONAHA.122.060315
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Stuart J Connolly Jeff S Healey Emilie P Belley-Cote Kumar Balasubramanian Domenico Paparella Katheryn Brady Wilko Reents Bernhard C Danner P J Devereaux Mukul Sharma Chinthanie Ramasundarahettige Salim Yusuf Richard P Whitlock Source Type: research

A comparative study of thoracoscopic left atrial appendage clipping versus stapled resection
CONCLUSIONS: The clipping group demonstrated a higher rate of complete LAA closure compared to the stapled resection group. Close monitoring of patients with residual LAA stumps is essential. Further research with larger cohorts is needed to elucidate impact of residual LAA stump on thromboembolic events.PMID:37734642 | DOI:10.1016/j.athoracsur.2023.09.010
Source: The Annals of Thoracic Surgery - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Suk Kyung Lim Chu Hyun Kim Ki Hong Choi Joong Hyun Ahn Young Keun On Sung Mok Kim Dong Seop Jeong Source Type: research

Prevalence of atrial septal defects and patent foramen ovale in a cohort of sudden cardiac death patients undergoing autopsy
CONCLUSIONS: The combined rate of PFO and ASD in a cohort of 517 patients undergoing autopsy was 7.9 %. None of these patients had experienced a cerebrovascular accident. This rate of PFOs appears lower than earlier reports and raises the possibility that the relative risk of an associated stroke could be higher than previously estimated.PMID:37734655 | DOI:10.1016/j.jjcc.2023.09.006
Source: Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Louise Fahy Stephanie Rowe Ziad Nehme Dion Stub Dominica Zentner Paul James Andreas Pflaumer Vanessa Connell Christopher Semsarian Jodie Ingles Andre La Gerche Elizabeth D Paratz Source Type: research

French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research

A cardiovascular polypill for secondary stroke prevention in a tertiary centre in Ghana (SMAART): a phase 2 randomised clinical trial
Lancet Glob Health. 2023 Oct;11(10):e1619-e1628. doi: 10.1016/S2214-109X(23)00347-9.ABSTRACTBACKGROUND: A cardiovascular polypill containing generic drugs might facilitate sustained implementation of and adherence to evidence-based treatments, especially in resource-limited settings. However, the impact of a cardiovascular polypill in mitigating atherosclerotic risk among stroke survivors has not been assessed. We aimed to compare a polypill regimen with usual care on carotid intima-media thickness (CIMT) regression after ischaemic stroke.METHODS: In SMAART, a phase 2 parallel, open-label, assessor-masked, randomised clini...
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Fred Stephen Sarfo Jenifer Voeks Sheila Adamu Benedict Apaw Agyei Manolo Agbenorku Nyantakyi Adu-Darko Mercy Adomah Oteng Vida Obese Rexford Adu Gyamfi Nathaniel Adusei Mensah Raelle Tagge Michael Ampofo Samuel Amoabeng Kontoh Samuel Blay Nguah Bruce Ovbi Source Type: research

Particulate matter air pollution is a significant risk factor for cardiovascular disease
This article discusses PM2.5 effects on the cardiovascular and pulmonary systems, specific PM2.5 pathophysiologic mechanisms contributing to cardiopulmonary disease, and preventive measures to limit the cardiovascular and pulmonary effects of PM2.5.PMID:37734693 | DOI:10.1016/j.cpcardiol.2023.102094
Source: Atherosclerosis - September 21, 2023 Category: Cardiology Authors: Robert J Henning Source Type: research

French National Diagnostic and Care Protocol for antiphospholipid syndrome in adults and children
Rev Med Interne. 2023 Sep 19:S0248-8663(23)00711-7. doi: 10.1016/j.revmed.2023.08.004. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic autoimmune disease involving vascular thrombosis and/or obstetric morbidity and persistent antibodies to phospholipids or certain phospholipid-associated proteins. It is a rare condition in adults and even rarer in children. The diagnosis of APS can be facilitated by the use of classification criteria based on a combination of clinical and biological features. APS may be rapidly progressive with multiple, often synchronous thromboses, resulting in life-threatening...
Source: Revue de Medecine Interne - September 21, 2023 Category: Internal Medicine Authors: Z Amoura B Bader-Meunier C Bal Dit Sollier A Belot Y Benhamou H Bezanahary F Cohen N Costedoat-Chalumeau L Darnige L Drouet E Elefant A Harroche M Lambert T Martin I Martin-Toutain A Mathian A Mekinian M Pineton De Chambrun L de Pontual D Wahl C Yelnik S Source Type: research

Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Poststroke Memory Disorder: A Meta-Analysis and Systematic Review
CONCLUSIONS: rTMS may improve memory function, global cognition, and the ability to perform ADL in patients with PSMD. LF-rTMS and HF-rTMS may have equal efficacy for treatment of PSMD. Future studies should consider extending the follow-up period to explore the safety and long-term efficacy of rTMS for treatment of PSMD and the appropriate choice of placebo for clinical trials of this treatment.PMID:37735134 | DOI:10.31083/j.jin2205131
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Haihua Xie Shiyang Luo Dan Xiong Pan Zhu Jie Chen Xin Tang Jie Tan Ning Zhao Source Type: research

Single-Cell RNA-Seq Reveals Changes in Cell Subsets in the Cortical Microenvironment during Acute Phase of Ischemic Stroke Rats
CONCLUSIONS: ScRNA-seq revealed the diversity of cell differentiation and the unique information of cell subpopulations in the cortex of rats with acute ischemic stroke, providing novel insight into the pathological process and drug discovery in stroke.PMID:37735120 | DOI:10.31083/j.jin2205128
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Yijin Zhao Chongwu Xiao Hui Chen Rui Zhu Meimei Zhang Haining Liu Xiaofeng Zhang Qing Zeng Guozhi Huang Source Type: research

Substance Abuse Greatly Raises Odds of Heart Attack, Stroke During Pregnancy
THURSDAY, Sept. 21, 2023 -- Substance abuse and pregnancy may be a dangerous combination. New research finds that pregnant women with a history of substance abuse had a dramatically increased risk of death from heart attack and stroke during...
Source: Drugs.com - Daily MedNews - September 21, 2023 Category: General Medicine Source Type: news

How Could Digital Technology Make An Impact On Primary Care?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail how primary care should be carried out in the future! Digital health should become an organic part of primary care in the future I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions by optimising my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests....
Source: The Medical Futurist - September 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research Healthcare Innovation technology wearables GP primary care general practitioner Source Type: blogs

Noncardiac comorbidities and intensive up ‐titration of oral treatment in patients recently hospitalized for heart failure: insights from the STRONG‐HF trial
ConclusionsIn the STRONG-HF trial, non-cardiac comorbidities neither limited the rapid up-titration of HF-therapies, nor attenuated the benefit of HIC on primary endpoint.In the context of a clinical trial, the benefit-risk ratio favors the rapid up-titration of HF-therapies even in patients with multiple NCCsThis article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - September 21, 2023 Category: Cardiology Authors: Ovidiu Chioncel, Beth Davison, Marianna Adamo, Laura E Antohi, Mattia Arrigo, Marianela Barros, Jan Biegus, Kamil ė Čerlinskaitė‐Bajorė, Jelena Celutkiene, Alain Cohen‐Solal, Albertino Damasceno, Rafael Diaz, Christopher Edwards, Gera Tags: Research Article Source Type: research

Cardiorespiratory coupling in the bottlenose dolphin (Tursiops truncatus)
Discussion: These data provide improved understanding of the cardiorespiratory coupling in dolphins, and show how both exhalation and inhalation alters ifH.
Source: Frontiers in Physiology - September 21, 2023 Category: Physiology Source Type: research