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Therapeutic potential of rWnt5A in curbing Leishmania donovani infection
Infection and Immunity, Ahead of Print.
Source: Infection and Immunity - September 19, 2023 Category: Infectious Diseases Authors: Shreyasi Maity Soham Sengupta Malini Sen 1 Division of Cancer Biology & Inflammatory Disorder, CSIR-Indian Institute of Chemical Biology , Kolkata, West Bengal, India Sunny Shin Source Type: research

Tangeretin Attenuates Cerebral Ischemia –Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2
In conclusion, TANG attenuates cerebral I/R-induced neuronal pyroptosis by inhibiting AIM2 inflammasome activation via regulating NRF2. These findings indicate TANG is a potential therapeutic agent for cerebral I/R injury.
Source: Inflammation - September 19, 2023 Category: Allergy & Immunology Source Type: research

Biomass yield, quality, nutrient composition, and feeding value of oat (Avena sativa) silage subjected to different wilting durations and/or inoculant application
In conclusion, inoculant may not affect the quality, composition and feeding values of ensiled oat grown without irrigation whereas, wilting at different durations may negatively affect the pH, smell, CP, ADF, and feeding values of ensiled oats.
Source: Tropical Animal Health and Production - September 19, 2023 Category: Veterinary Research Source Type: research

Effects of temporal and spatial scales on soil yeast communities in the peach orchard
Shihezi Reclamation Area is located at the southern edge of the Junggar Basin, with natural, soil, and climatic conditions unique to the production of peaches. In turn, peach orchards have accumulated rich microbial resources. As an important taxon of soil fungi, the diversity and community structure changes of yeast in the soil of peach orchards on spatial and temporal scales are still unknown. Here, we aimed to investigate the changes in yeast diversity and community structure in non-rhizosphere and rhizosphere soils of peach trees of different ages in the peach orchard and the factors affecting them, as well as the chan...
Source: Frontiers in Microbiology - September 19, 2023 Category: Microbiology Source Type: research

Radio Frequency Based Sensor for Adulteration Measurement in a Continuous Two Phase-Flow of Alcoholic Beverages
AbstractThe adulteration in alcoholic beverage has costed thousands of lives and malnutrition ’s specifically in developing countries. The existing characterization methods such as Gas Chromatography (GC) and Bioassay and Spectroscopy (NMR) offer insights into the chemical composition but the techniques are costlier and bulkier, hence the testing is evitable in a limited number of cases. T his paper discloses the novel radio frequency (RF) technology based sensors and integrated into a device to detect the presence of ethanol in beverages. The proposed sensor is two phase flow sensor as the liquid can continuously move w...
Source: Sensing and Imaging - September 19, 2023 Category: Biomedical Engineering Source Type: research

Exploring the leishmanicidal potential of terpenoids: a comprehensive review on mechanisms of cell death
Leishmaniasis is a neglected tropical disease with a wide spectrum of clinical manifestations, ranging from visceral to cutaneous, with millions of new cases and thousands of deaths reported each year. The species of Leishmania and the immune response of the host determine the severity of the disease. Leishmaniasis remains challenging to diagnose and treat, and there is no vaccine available. Several studies have been conducted on the use of herbal medicines for the treatment of leishmaniasis. Natural products can provide an inexhaustible source of chemical diversity with therapeutic potential. Terpenes are a class of natur...
Source: Frontiers in cellular and infection microbiology - September 19, 2023 Category: Microbiology Source Type: research

The best peel and stick wallpaper and tiles of 2023
Staring at bare white walls when you first move into a new apartment can almost feel like looking at an empty canvas. Should you repaint, invest in wallpaper or just hang up a large tapestry? If you’re just as indecisive as I am, something like peel and stick wallpaper or peel and stick tile might…#diy #jenniferhunter #newyorkcity #ny #select #nbcselect #nikkibrown #zoemalin #malin #spoonflower
Source: Reuters: Health - September 18, 2023 Category: Consumer Health News Source Type: news

High-Density Surface EMG Decomposition by Combining Iterative Convolution Kernel Compensation With an Energy-Specific Peel-off Strategy
Conclusion- The high yield and accuracy of MUs decomposed from simulated and experimental HD-sEMG signals demonstrate the superiority of the proposed framework in decomposing low-energy MUs compared to existing methods for HD-sEMG signal decomposition. Significance- The proposed framework enables us to construct a more representative motor unit pool, consequently enhancing our understanding pertaining to various neuropathological conditions and providing invaluable information for the diagnosis and treatment of neuromuscular disorders and motor neuron diseases.
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 18, 2023 Category: Neuroscience Source Type: research

Noncovalent interactions of aromatic heterocycles: rotational spectroscopy and theoretical calculations of the thiazole –CF4 and thiazole–SF6 complexes
Phys. Chem. Chem. Phys., 2023, Advance Article DOI: 10.1039/D3CP02363J, PaperTingting Yang, Yugao Xu, Zhen Wang, Chunmei Feng, Gang Feng The non-covalent bonding features of the complexes of thiazole with CF4 and SF6 were investigated by means of high-resolution rotational spectroscopy and quantum chemical calculations. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 18, 2023 Category: Chemistry Authors: Tingting Yang Source Type: research

A reactive matrix for in-situ chemical derivatization and specific detection of cis-diol compounds by matrix-assisted laser desorption/ionization mass spectrometry
Analyst, 2023, Accepted Manuscript DOI: 10.1039/D3AN01400B, PaperJiajing Chen, huan Huang, Dan Ouyang, Jiali Lin, Zhuling Chen, Zongwei Cai, Zian Lin Analysis of cis-diol compounds is essential, because it play important roles in cosmetics, food, pharmaceuticals, and living organism. Herein, we developed a matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) method to... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - September 18, 2023 Category: Chemistry Authors: Jiajing Chen Source Type: research

Exceptional peroxidase-like activity of an iron and copper based organic framework nanosheet for consecutive colorimetric biosensing of glucose and kanamycin in real food samples
Analyst, 2023, Advance Article DOI: 10.1039/D3AN01242E, PaperRajakumari Jesuraj, Arunjegan Amalraj, Vinoth Kumar Vaidyanathan, Panneerselvam Perumal Two-dimensional metal –organic framework nanosheets are attractive as peroxidase mimicking nanocatalysts due to their rich chemical functional groups, large surface area, high porosity, and accessible active sites. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - September 18, 2023 Category: Chemistry Authors: Rajakumari Jesuraj Source Type: research

Advances in urinary biomarker research of synthetic cannabinoids - Wang Z, Leow EYQ, Moy HY, Chan ECY.
New psychoactive substances (NPS) are chemical compounds designed to mimic the action of existing illicit recreational drugs. Synthetic cannabinoids (SCs) are a subclass of NPS which bind to the cannabinoid receptors, CB1 and CB2, and mimic the action of c...
Source: SafetyLit - September 18, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Skin wound healing effects of (+)-syringaresinol from ginseng berry
CONCLUSION: Collectively, we demonstrated that (+)-SYR from ginseng berry, can enhance the wound healing effect by accelerating cell proliferation and skin regeneration, suggesting the potential utility of (+)-SYR for skin wound repair.PMID:37720576 | PMC:PMC10499580 | DOI:10.1016/j.jgr.2023.04.003
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Jee-Hyun Hwang Yeonsoo Kang Heui-Jin Park Seolyeong Kim Su-Hyun Lee Hangun Kim Sang-Jip Nam Kyung-Min Lim Source Type: research

Modeling Gut Neuro-Epithelial Connections in a Novel Microfluidic Device
We describe the development of a two-compartment microfluidic device for modeling neuro-epithelial interactions, and apply it to form the gut's neuro-epithelial connections. The device contains epithelial and neuronal compartments connected by microgrooves. The epithelial compartment was designed for cell seeding via injection and confinement of intestinal epithelial cells derived from human intestinal organoids. We demonstrated that organoids planarized effectively and retained epithelial phenotype for over a week. In the second chamber we dissociated and cultured intestinal myenteric neurons including intrinsic primary a...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Manolo De Hoyos Xi Yu Alan Gonzalez-Suarez Arnaldo Mercado-Perez Eugene Krueger Jeric Hernandez Brooke Druliner David R Linden Arthur Beyder Sisi Chen Yaroslav Fedyshyn Alexander Revzin Source Type: research

Polysaccharide-Based Double-Network Hydrogels: Polysaccharide Effect, Strengthening Mechanisms, and Applications
Biomacromolecules. 2023 Sep 17. doi: 10.1021/acs.biomac.3c00765. Online ahead of print.ABSTRACTPolysaccharides are carbohydrate polymers that are major components of plants, animals, and microorganisms, with unique properties. Biological hydrogels are polymeric networks that imbibe and retain large amounts of water and are the major components of living organisms. The mechanical properties of hydrogels are critical for their functionality and applications. Since synthetic polymeric double-network (DN) hydrogels possess unique network structures with high and tunable mechanical properties, many natural functional polysaccha...
Source: Biomacromolecules - September 18, 2023 Category: Biochemistry Authors: Pengguang Wang Qingyu Liao Hongbin Zhang Source Type: research