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Hit by Scandal, Petro Can Still Ruin Colombia
Daniel RaisbeckLess than a  year ago, I wrote of the almost certain regret that awaited the prosperous, urban, multiple ‐​degree‐​holding types who voted for Gustavo Petro, Colombia’s Chavista president. They thought they had supported a Nordic‐​style social democrat—failing to notice that they had helped to elect a tropical socialist who, given his past as a guerrilla group member and Hugo Chávez supporter, was also a potential autocrat.Caveat emptor (or rathersuffragator) indeed. But I  never thought that voter’s remorse would set in so quickly. Or so extremely.According to poll data from June 1...
Source: Cato-at-liberty - June 11, 2023 Category: American Health Authors: Daniel Raisbeck Source Type: blogs

Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Video Capsule Navigates the Stomach
Researchers at George Washington University have created a swallowable capsule containing a video camera that can assist in identifying lesions in the stomach. However, unlike similar devices that have been developed previously, this capsule can driv...
Source: Medgadget - June 9, 2023 Category: Medical Devices Authors: Conn Hastings Tags: GI GWToday GWTweets Source Type: blogs

Belong.Life Provides Holistic Online Patient Communities
Patients throng to communities where they can get practical life advice in a depth that only fellow patients can offer. Belong.Life is an online community and app designed to combine many forms of support patients benefit from. According to Irad Deutsch, co-founder and CTO, the average patient engages on the platform 15 times per month, demonstrating its value. The condition for which Belong.Life was created was cancer, but they have branched out into many other conditions. They now allow other organizations, such as pharmaceutical companies and hospitals, create communities there. A patient who receives a diagnosis is oft...
Source: EMR and HIPAA - June 9, 2023 Category: Information Technology Authors: John Lynn Tags: Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Belong.life Cancer Apps Healthcare AI Healthcare Generative AI Healthcare IT Video Interviews HIMSS HIMSS 2023 HIMSS23 Patient Source Type: blogs

How modern lifestyle changes are disrupting our immune systems
In addition to a steep increase in prevalence, in recent decades, we have seen an evolution in the ways our immune system misbehaves: eosinophilic esophagitis, mast cell disorders, and early onset colon cancer, among many others. This data alone should remind us that we are an ever-evolving species. With our rapidly changing lifestyle over the Read more… How modern lifestyle changes are disrupting our immune systems originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - June 9, 2023 Category: General Medicine Authors: Tags: Conditions Allergies & Immunology Source Type: blogs

Intermittent Senolytic Treatment with Dasatinib and Quercetin Produces Benefits in Non-Human Primates
Researchers here report on the outcome of six months of monthly senolytic therapy in cynomolgus macaques. The results are broadly positive, as one might expect from the established human data. Dasatinib is a chemotherapeutic drug, but senolytic dosing is not sustained as is the case in the treatment of cancer, and side-effects are much reduced as a result. It remains to be seen as to what the optimal dose and dose schedule for this treatment will be. Researchers are trying a range of options, and arguably the human trials conducted by the Mayo Clinic are using too low a dose. Time will tell, but there is a need for more cl...
Source: Fight Aging! - June 9, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Diet That Prevents Prostate Cancer And Speeds Recovery
The nutrients that may halt one of the deadliest cancers in men and speed up their recovery after radiotherapy.
Source: PsyBlog | Psychology Blog - June 8, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Cancer Source Type: blogs

Clinical radiology workforce census 2022
The Royal College of Radiologists -This survey secured a 100 per cent response rate with every single cancer centre head and clinical director of radiology departments responding. The report demonstrates the scale of workforce shortages in diagnostic and cancer departments across the country and the devastating impact on cancer patients. It is published alongside theoncology workforce census results.ReportThe Royal College of Radiologists - news
Source: Health Management Specialist Library - June 8, 2023 Category: UK Health Authors: The King ' s Fund Library Tags: Workforce and employment Source Type: blogs

Surveying Laboratory Tests From a Health IT Perspective
We read that “70% of today’s medical decisions depend on laboratory test results,” according to the CDC. This three-part series looks at modern tests from a health IT perspective. How can we make them more accurate and delivery faster results? Which ones can we move into the home? How do we eliminate wasteful, unnecessary tests? This first article offer an overview of tests and their context. Overview of Testing Gerry Miller, founder and CEO of Cloudticity, classifies the value of a test by several factors: How easy is the test to acquire? How complex is the test to administer? How much does it cost? Most im...
Source: EMR and HIPAA - June 7, 2023 Category: Information Technology Authors: Andy Oram Tags: Health IT Company Healthcare IT Interoperability CDC CLIA Cloudicity Direct to Consumer Lab Testing Dr. Yair Lewis Epstein Becker Green Gerry Miller Healthcare Interoperability IVD Laboratories Labs Navina Robert Hearn Sand Source Type: blogs

The Gut Microbiome Differs in Characteristic Ways in Patients with Precancerous Colon Polyps
The gut microbiome changes with age, the relative abundance of microbial populations shifting in ways that appear connected to chronic inflammation and dysfunction of the intestinal epithelium and intestinal barrier function. Cancer of the colon is an important cause of human mortality, and there is some hope that finding ways to prevent or reverse gut microbiome aging, such as via fecal microbiota transplant from young individuals, will go some way to minimizing colon cancer incidence. Colorectal cancer is the second leading cause of cancer-related death in the U.S., and rates of colorectal cancer are rising amon...
Source: Fight Aging! - June 7, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

An Example of In Silico Drug Screening for Senolytic Compounds
The average small molecule drug development program starts with a mechanism, an intended outcome such as inhibition, and then screening of as many molecules as possible from the libraries. Sometimes it is possible to make educated guesses as to what types of molecule are more likely to be useful, but often screening must be very broad and with little direction. In principle, low cost computation makes it possible to dramatically reduce the cost of discovery of useful molecules given a specific target mechanism. This shift from physical to in silico screening has been underway for a while, for example at Insilico Medicine, ...
Source: Fight Aging! - June 5, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Matthew ’s health care tidbits: Hedge Funds that Do Health Care on the Side
Each time I send out the THCB Reader, our newsletter that summarizes the best of THCB (Sign up here!) I include a brief tidbits section. Then I had the brainwave to add them to the blog. They’re short and usually not too sweet! –Matthew Holt Lots of news about bad behavior in health care this week, with real shots about patient & staff safety at home care company Papa, and Grail misinforming 400 people that they had cancer. But the prize for tone deafness this week comes from another very well funded health care provider system being heartless to its poorest patients.  This week it’s Allina, a Minn...
Source: The Health Care Blog - June 5, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt Allina Ascension UPMC Source Type: blogs

SENS Research Foundation ' s Senotherapeutic Screening Project is Now Crowdfunding at Experiment
Experiment is a crowdfunding platform for small scientific projects. It has been running for quite a few years now, one of the few survivors from the first wave of attempts to make crowdfunding platforms to fund scientific research. It is a challenging goal, the motivations and incentives are completely different from those operating in commercial product crowdfunding. SENS Research Foundation is now using Experiment to raise a modest amount of funds for a senotherapeutic screening program. The Foundation does good work, and I donated. That part of the industry presently seeking approaches to clear senescent cells, ...
Source: Fight Aging! - June 5, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, June 5th 2023
In conclusion, higher BMR might reduce lifespan. The underlying pathways linking to major causes of death and relevant interventions warrant further investigation. Betting Against Progress Turns Out Poorly, But Can Work in the Short Term in a Slow Field https://www.fightaging.org/archives/2023/06/betting-against-progress-turns-out-poorly-but-can-work-in-the-short-term-in-a-slow-field/ Setting oneself up as a spokesperson for "we will not achieve this goal", as the fellow noted here is choosing to do, is a bet against technological progress. A glance at any few decade period in the past two hundred year...
Source: Fight Aging! - June 4, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Proposed USPSTF guideline update: Advocating for earlier breast cancer screening at age 40
Pop Quiz: At what age do medical experts recommend women of average risk for breast cancer begin receiving screening mammograms? 40 45 50 All of the above. If you answered “D,” you are correct. Confused? I don’t blame you. Medical societies and independent task forces do not agree on when to begin or end screening Read more… Proposed USPSTF guideline update: Advocating for earlier breast cancer screening at age 40 originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - June 3, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs