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Total 178978 results found since Jan 2013.
Attenuation of celecoxib cardiac toxicity using Poly( δ-decalactone) based nanoemulsion via oral route
Eur J Pharm Sci. 2023 Sep 15:106585. doi: 10.1016/j.ejps.2023.106585. Online ahead of print.ABSTRACTCelecoxib (CLX), a poorly soluble anti-inflammatory drug, requires administration in higher concentrations to produce therapeutic effects, oftentimes resulting in cardiac toxicity. Therefore, in this study, we employed a nanoemulsion technology to improve the solubility of CLX using poly(δ-decalactone) (PDL) polymer as an oil and mPEG-b-PDL as a surfactant. The nanoemulsion (NE) was successfully prepared via the nanoprecipitation method. In vitro characterization was performed for size, drug release, and stability. In vivo ...
Source: European Journal of Pharmaceutical Sciences - September 17, 2023 Category: Drugs & Pharmacology Authors: Saurabh Maru Jyoti Verma Carl-Eric Wilen Jessica M Rosenholm Kuldeep K Bansal Source Type: research
Superwettable cellulose acetate-based nanofiber membrane with spider-web structure for highly efficient oily water purification
This study provides a novel strategy for the construction of the high-performance oil/water separation membrane.PMID:37717870 | DOI:10.1016/j.ijbiomac.2023.126865
Source: International Journal of Biological Macromolecules - September 17, 2023 Category: Biochemistry Authors: Doudou Ning Zhaoqing Lu Cuiyu Tian Ning Yan Fan Xie Nan Li Li Hua Source Type: research
Phytotoxicity of weathered petroleum hydrocarbons in soil to boreal plant species
This study indicates that natural weathering of Fraction 2- and Fraction 3-concentrated soil did not eliminate phytotoxicity to boreal plant species. Furthermore, it builds on the limited existing literature for toxicity of PHCs on boreal plants and supports site remediation to existing Canadian provincial PHC guidelines.PMID:37717802 | DOI:10.1016/j.envres.2023.117136
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Prama Roy Allison Rutter Amy Gainer Elizabeth Haack Barbara A Zeeb Source Type: research
Efficiency of Optimal Fluoroscopic Projection Angle defined by Computed Tomography Angiography for Left Atrial Appendage Closure
CONCLUSION: By unfolding the LAA depth and orifice diameter to a better view, OPA demonstrated the potential to optimize LAAC procedural efficiency, although further larger-scale studies are required to confirm this.PMID:37717695 | DOI:10.1016/j.hjc.2023.09.009
Source: Hellenic Journal of Cardiology - September 17, 2023 Category: Cardiology Authors: Xu Lu Xinyan Wang Qingsong Wang Tingting Song Ge Liu Ao Liu Xiangmin Shi Jun Guo Tao Chen Source Type: research
Efficient biotransformation of docosahexaenoic acid-rich oils into the lipid mediator resolvin D5 by cells expressing 15S-lipoxygenase using a bioreactor
This study will contribute to the large-scale production of SPMs from oils.PMID:37717704 | DOI:10.1016/j.biortech.2023.129750
Source: Bioresource Technology - September 17, 2023 Category: Biotechnology Authors: Jin Lee Hyun-Ah Park Kyung-Chul Shin Jin-Byung Park Deok-Kun Oh Source Type: research
Production of extracellular superoxide radical in microorganisms and its environmental implications: A review
Environ Pollut. 2023 Sep 15:122563. doi: 10.1016/j.envpol.2023.122563. Online ahead of print.ABSTRACTExtracellular superoxide radical (O2•-) is ubiquitous in microbial environments and has significant implications for pollutant transformation. Microbial extracellular O2•- can be produced through multiple pathways, including electron leakage from the respiratory electron transport chain (ETC), NADPH oxidation by the transmembrane NADPH oxidase (NOX), and extracellular reactions. Extracellular O2•- significantly influences the geochemical processes of various substances, including toxic metals and refractory organic po...
Source: Environmental Pollution - September 17, 2023 Category: Environmental Health Authors: Zhanfei He Qunqun Li Yao Xu Daoyong Zhang Xiangliang Pan Source Type: research
Efficiency of Optimal Fluoroscopic Projection Angle defined by Computed Tomography Angiography for Left Atrial Appendage Closure
CONCLUSION: By unfolding the LAA depth and orifice diameter to a better view, OPA demonstrated the potential to optimize LAAC procedural efficiency, although further larger-scale studies are required to confirm this.PMID:37717695 | DOI:10.1016/j.hjc.2023.09.009
Source: Hellenic Journal of Cardiology - September 17, 2023 Category: Cardiology Authors: Xu Lu Xinyan Wang Qingsong Wang Tingting Song Ge Liu Ao Liu Xiangmin Shi Jun Guo Tao Chen Source Type: research
Risky driving behaviors and employer motor vehicle safety policies among U.S. oil and gas extraction workers
CONCLUSIONS: Workers whose employers lacked motor vehicle safety policies were more likely to engage in risky driving behaviors.PRACTICAL APPLICATIONS: Results of this survey support the implementation of motor vehicle safety interventions such as bans on texting and handheld and hands-free cell phone use, speed management, and in-vehicle monitoring systems by OGE employers as well as research focusing on the effectiveness of these interventions in OGE. Additional research could examine worker driving behaviors through self-reported data in combination with objective measures.PMID:37718039 | PMC:PMC10505701 | DOI:10.1016/j.jsr.2023.05.015
Source: Cell Research - September 17, 2023 Category: Cytology Authors: Kaitlin C Wingate Stephanie Pratt Alejandra Ramirez-Cardenas Kyla Hagan-Haynes Source Type: research
Attenuation of celecoxib cardiac toxicity using Poly( δ-decalactone) based nanoemulsion via oral route
Eur J Pharm Sci. 2023 Sep 15:106585. doi: 10.1016/j.ejps.2023.106585. Online ahead of print.ABSTRACTCelecoxib (CLX), a poorly soluble anti-inflammatory drug, requires administration in higher concentrations to produce therapeutic effects, oftentimes resulting in cardiac toxicity. Therefore, in this study, we employed a nanoemulsion technology to improve the solubility of CLX using poly(δ-decalactone) (PDL) polymer as an oil and mPEG-b-PDL as a surfactant. The nanoemulsion (NE) was successfully prepared via the nanoprecipitation method. In vitro characterization was performed for size, drug release, and stability. In vivo ...
Source: European Journal of Pharmaceutical Sciences - September 17, 2023 Category: Drugs & Pharmacology Authors: Saurabh Maru Jyoti Verma Carl-Eric Wilen Jessica M Rosenholm Kuldeep K Bansal Source Type: research
Exploring the bioremediation capability of petroleum-contaminated soils for enhanced environmental sustainability and minimization of ecotoxicological concerns
Environ Sci Pollut Res Int. 2023 Sep 18. doi: 10.1007/s11356-023-29801-1. Online ahead of print.ABSTRACTThe bioremediation of soils contaminated with petroleum hydrocarbons (PHCs) has emerged as a promising approach, with its effectiveness contingent upon various types of PHCs, i.e., crude oil, diesel, gasoline, and other petroleum products. Strategies like genetically modified microorganisms, nanotechnology, and bioaugmentation hold potential for enhancing remediation of polycyclic aromatic hydrocarbon (PAH) contamination. The effectiveness of bioremediation relies on factors such as metabolite toxicity, microbial competi...
Source: Environmental Science and Pollution Research International - September 17, 2023 Category: Environmental Health Authors: Rida Zainab Maria Hasnain Faraz Ali Daniel Anthony Dias Ali El-Keblawy Zainul Abideen Source Type: research
Attenuation of celecoxib cardiac toxicity using Poly( δ-decalactone) based nanoemulsion via oral route
Eur J Pharm Sci. 2023 Sep 15:106585. doi: 10.1016/j.ejps.2023.106585. Online ahead of print.ABSTRACTCelecoxib (CLX), a poorly soluble anti-inflammatory drug, requires administration in higher concentrations to produce therapeutic effects, oftentimes resulting in cardiac toxicity. Therefore, in this study, we employed a nanoemulsion technology to improve the solubility of CLX using poly(δ-decalactone) (PDL) polymer as an oil and mPEG-b-PDL as a surfactant. The nanoemulsion (NE) was successfully prepared via the nanoprecipitation method. In vitro characterization was performed for size, drug release, and stability. In vivo ...
Source: European Journal of Pharmaceutical Sciences - September 17, 2023 Category: Drugs & Pharmacology Authors: Saurabh Maru Jyoti Verma Carl-Eric Wilen Jessica M Rosenholm Kuldeep K Bansal Source Type: research
Cocaine is about surpass oil as Colombia ' s top export as revenues near $20 billion
None Cocaine is set to become Colombia's top export this year, edging out oil products, according to a note from Bloomberg Economics. • None Revenue derived from Colombia's cocaine business is nearing $20 billion, ahead of the country's $19.1 billion in 2022 oil exports. • None Cocaine production…#nonecocaine #colombia #bloombergeconomics #nonerevenue #colombian #gustavopetro #felpihernandez #hernandez
Source: Reuters: Health - September 17, 2023 Category: Consumer Health News Source Type: news
A cross talk based critical analysis of solvent free microwave extraction to accentuate it as the new normal for extraction of essential oil: an attempt to overhaul the science of distillation through a comprehensive tutelage
Source: Critical Reviews in Food Science and Nutrition - September 17, 2023 Category: Nutrition Authors: Mukherjee, Souvik Chouhan, Kavi Bhushan Singh Chandrakar, Monika Gupta, Pragya Lal, Kajal Mandal, Vivekananda Source Type: research
California sues oil companies claiming they downplayed the risk of fossil fuels
California has filed a lawsuit against some of the world’s largest oil and gas companies, claiming they deceived the public and downplayed the risks posed by fossil fuels. The civil lawsuit filed in state Superior Court in San Francisco also seeks creation of a fund – financed by the companies –…#superiorcourt #gavinnewsom #exxonmobil #chevron #conocophillips #bp #bigoil #newsom #ryanmeyers #kathymulvey
Source: Reuters: Health - September 17, 2023 Category: Consumer Health News Source Type: news
