Now the CDC wants to monitor your POOP to track flu outbreaks - after pioneering 'wastewater surveillance' during Covid pandemic
So-called wastewater surveillance was pioneered during the pandemic to track new variants and gave officials early warning of flare-ups in the UK and US.
Source: the Mail online | Health - September 14, 2023 Category: Consumer Health News Source Type: news

Interim Effectiveness Estimates of 2023 Southern Hemisphere Influenza Vaccines in Preventing Influenza-Associated Hospitalizations - REVELAC-i Network, March-July 2023
This report describes flu vaccine effectiveness data from five South American countries during the 2023 Southern Hemisphere flu season.
Source: CDC Morbidity and Mortality Weekly Report - September 14, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news

Wastewater Surveillance Data as a Complement to Emergency Department Visit Data for Tracking Incidence of Influenza A and Respiratory Syncytial Virus - Wisconsin, August 2022-March 2023
This report describes how emergency department visits and wastewater surveillance data were used to track influenza and respiratory syncytial virus activity in Wisconsin.
Source: CDC Morbidity and Mortality Weekly Report - September 14, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news

Immune Response Not Inferior With Coadministration of COVID-19, Flu Shots
THURSDAY, Sept. 14, 2023 -- The immune response and occurrence of adverse events were similar for health care workers receiving coadministration of COVID-19 and influenza vaccines or COVID-19 vaccine alone, according to a study published online...
Source: Drugs.com - Pharma News - September 14, 2023 Category: Pharmaceuticals Source Type: news

Tennessee piano starlet Mathias Uribe, 14, has his hands AND feet AMPUTATED after flu-like illness led to deadly toxic shock syndrome
Mathias Uribe, 14, from Sumer County, became ill with what appeared to be just a regular cold in mid-June but within weeks could barely breathe and was rushed to the ER.
Source: the Mail online | Health - September 14, 2023 Category: Consumer Health News Source Type: news

Ontario proposes letting pharmacists prescribe flu meds, give RSV vaccines
Ontario is planning to allow pharmacists to prescribe flu medication, administer flu shots to babies and administer RSV vaccines, when available, ahead of an expected fall viral surge.
Source: CBC | Health - September 14, 2023 Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news

The Petri Dish: Former bluebird CFO to lead startup, Moderna flu vaccine succeeds in Phase 3
The CFO who left bluebird bio last fall after nearly nine years has found a new roost. Plus other life sciences news you may have missed.
Source: bizjournals.com Health Care:Biotechnology headlines - September 14, 2023 Category: Biotechnology Authors: Rowan Walrath Source Type: news

The long-term safety and tolerability of anifrolumab for patients with systemic lupus erythematosus in Japan: TULIP-LTE subgroup analysis
CONCLUSIONS: Anifrolumab 300 mg showed a favourable benefit-risk profile for the long-term treatment of adult patients with moderate to severe SLE from Japan, with safety, tolerability, and efficacy profiles consistent with the overall population.PMID:37706527 | DOI:10.1093/mr/road092
Source: Herpes - September 14, 2023 Category: Infectious Diseases Authors: Yoshiya Tanaka Tatsuya Atsumi Masato Okada Tomoya Miyamura Tomonori Ishii Susumu Nishiyama Ryutaro Matsumura Atsushi Kawakami Nobuya Hayashi Gabriel Abreu Sule Yavuz Catharina Lindholm Hussein Al-Mossawi Tsutomu Takeuchi Source Type: research

Recommendations to Improve the Influenza Immunization Rates of Respiratory Healthcare Professionals: A Survey Conducted in Puerto Rico
CONCLUSION: This survey among respiratory HC professionals in Puerto Rico demonstrated barriers in knowledge about vaccination, its indications, and its safety. Addressing these barriers provides us with opportunities to improve influenza immunizations rates among HC workers and their patients.PMID:37709677
Source: Puerto Rico Health Sciences Journal - September 14, 2023 Category: International Medicine & Public Health Authors: Giannina Coppola-Fasick Lorena Gonz ález-Sepúlveda Yanira Arce-Ayala Cristina Ramos-Romey Sylvette Nazario Source Type: research

The long-term safety and tolerability of anifrolumab for patients with systemic lupus erythematosus in Japan: TULIP-LTE subgroup analysis
CONCLUSIONS: Anifrolumab 300 mg showed a favourable benefit-risk profile for the long-term treatment of adult patients with moderate to severe SLE from Japan, with safety, tolerability, and efficacy profiles consistent with the overall population.PMID:37706527 | DOI:10.1093/mr/road092
Source: Herpes - September 14, 2023 Category: Infectious Diseases Authors: Yoshiya Tanaka Tatsuya Atsumi Masato Okada Tomoya Miyamura Tomonori Ishii Susumu Nishiyama Ryutaro Matsumura Atsushi Kawakami Nobuya Hayashi Gabriel Abreu Sule Yavuz Catharina Lindholm Hussein Al-Mossawi Tsutomu Takeuchi Source Type: research

Analysis of polygenic selection in purebred and crossbred pig genomes using generation proxy selection mapping
CONCLUSIONS: This work confirms the efficacy and the negligible error rates of the GPSM method in detecting selected loci in commercial pig populations. Our results suggest shared selection objectives and genetic architectures across swine populations. The identified polygenic selection highlights loci that are important to swine production.PMID:37710159 | DOI:10.1186/s12711-023-00836-9
Source: Genet Sel Evol - September 14, 2023 Category: Genetics & Stem Cells Authors: Caleb J Grohmann Caleb M Shull Tamar E Crum Clint Schwab Timothy J Safranski Jared E Decker Source Type: research

Innate immune escape and adaptive immune evasion of African swine fever virus: A review
Virology. 2023 Sep 7;587:109878. doi: 10.1016/j.virol.2023.109878. Online ahead of print.ABSTRACTAfrican swine fever virus (ASFV) causes hemorrhagic fever in domestic and wild pigs. The continued spread of the virus in Africa, Europe and Asia threatens the global pig industry. The lack of an effective vaccine limits disease control. ASFV has evolved a variety of encoded immune escape proteins and can evade host adaptive immunity, inducing cellular inflammation, autophagy, or apoptosis in host cells. Frequent persistent infections hinder the development of a viral vaccine and impose technical barriers. Currently, knowledge ...
Source: Virology - September 14, 2023 Category: Virology Authors: Sai Niu Yilin Guo Xueying Wang Zixuan Wang Limeng Sun Hanchuan Dai Guiqing Peng Source Type: research

Interim Effectiveness Estimates of 2023 Southern Hemisphere Influenza Vaccines in Preventing Influenza-Associated Hospitalizations - REVELAC-i Network, March-July 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 15;72(37):1010-1015. doi: 10.15585/mmwr.mm7237e1.NO ABSTRACTPMID:37708084 | DOI:10.15585/mmwr.mm7237e1
Source: MMWR Morb Mortal Wkl... - September 14, 2023 Category: Epidemiology Authors: Ashley L Fowlkes Francisco Nogareda Annette Regan Sergio Loayza Jose Mendez Mancio Lindsey M Duca Paula Couto Juliana Leite Angel Rodriguez Daniel Salas Eduardo Azziz-Baumgartner REVELAC –i Network Source Type: research

Wastewater Surveillance Data as a Complement to Emergency Department Visit Data for Tracking Incidence of Influenza A and Respiratory Syncytial Virus - Wisconsin, August 2022-March 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 15;72(37):1005-1009. doi: 10.15585/mmwr.mm7237a2.ABSTRACTWastewater surveillance has been used to assist public health authorities in tracking local transmission of SARS-CoV-2. The usefulness of wastewater surveillance to track community spread of other respiratory pathogens, including influenza virus and respiratory syncytial virus (RSV), is less clear. During the 2022-23 respiratory diseases season, concentrations of influenza A virus and RSV in wastewater samples in three major Wisconsin cities were compared with emergency department (ED) visits associated with these pathogens. In all...
Source: MMWR Morb Mortal Wkl... - September 14, 2023 Category: Epidemiology Authors: Peter M DeJonge Carly Adams Ian Pray Melissa K Schussman Rebecca B Fahney Martin Shafer Dagmara S Antkiewicz Ad élaïde Roguet Source Type: research

Nucleic Acid Detection through RNA-Guided Protease Activity in Type III-E CRISPR-Cas Systems
Chembiochem. 2023 Sep 14:e202300401. doi: 10.1002/cbic.202300401. Online ahead of print.ABSTRACTRNA-guided protease activity was recently discovered in the type III-E CRISPR-Cas systems (Craspase), providing a novel platform for engineering a protein probe instead of the commonly used nucleic acid probe in the nucleic acid detection assays. Here, by adapting a fluorescence readout technique using the affinity- and fluorescent protein dual-tagged Csx30 protein substrate, we established an assay monitoring Csx30 cleavage by target ssRNA-activated Craspase. Four Craspase-based nucleic acid detection systems for genes from sev...
Source: Chembiochem - September 14, 2023 Category: Biochemistry Authors: Qiuqiu He Xinlong Lei Yuanjun Liu Xiaoshen Wang Nan Ji Hang Yin Huiping Wang Heng Zhang Guimei Yu Source Type: research

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