Diverse roles of lung macrophages in the immune response to influenza A virus
Influenza viruses are one of the major causes of human respiratory infections and the newly emerging and re-emerging strains of influenza virus are the cause of seasonal epidemics and occasional pandemics, resulting in a huge threat to global public health systems. As one of the early immune cells can rapidly recognize and respond to influenza viruses in the respiratory, lung macrophages play an important role in controlling the severity of influenza disease by limiting viral replication, modulating the local inflammatory response, and initiating subsequent adaptive immune responses. However, influenza virus reproduction i...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

Archaeome structure and function of the intestinal tract in healthy and H1N1 infected swine
Conclusions/Take home messageFinally, this study provides the first multi-omics analysis and high-resolution insights into the structure and function of the porcine intestinal tract archaeome during a non-lethal Influenza A virus infection of the respiratory tract, demonstrating significant alterations in archaeal community composition and central metabolic functions.
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

The oxidative stress response of Streptococcus pneumoniae: its contribution to both extracellular and intracellular survival
Streptococcus pneumoniae is a gram-positive, aerotolerant bacterium that naturally colonizes the human nasopharynx, but also causes invasive infections and is a major cause of morbidity and mortality worldwide. This pathogen produces high levels of H2O2 to eliminate other microorganisms that belong to the microbiota of the respiratory tract. However, it also induces an oxidative stress response to survive under this stressful condition. Furthermore, this self-defense mechanism is advantageous in tolerating oxidative stress imposed by the host’s immune response. This review provides a comprehensive overview of the strateg...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

Influenza viruses circulation in a tertiary care children hospital in Rome: a comparison between 2022 and the previous 5 years
Influenza surveillance aims to determine onset, duration and intensity of the seasonal Influence-like Illness (ILI); data collection begins in the week 42 of a year and ends in the week 17 of the following yea...
Source: Italian Journal of Pediatrics - September 13, 2023 Category: Pediatrics Authors: Stefania Ranno, Luana Coltella, Giulia Linardos, Velia Chiara Di Maio, Luna Colagrossi, Leonarda Gentile, Eugenia Galeno, Marta Luisa Ciofi degli Atti, Sebastian Cristaldi, Alberto Villani, Massimiliano Raponi, Carlo Federico Perno and Cristina Russo Tags: Research Source Type: research

Genomic classification and antimicrobial resistance profiling of Streptococcus pneumoniae and Haemophilus influenza isolates associated with paediatric otitis media and upper respiratory infection
Acute otitis media (AOM) is the most common childhood bacterial infectious disease requiring antimicrobial therapy. Most cases of AOM are caused by translocation of Streptococcus pneumoniae or Haemophilus influen...
Source: BMC Infectious Diseases - September 13, 2023 Category: Infectious Diseases Authors: Briallen Lobb, Matthew C. Lee, Christi L. McElheny, Yohei Doi, Kristin Yahner, Alejandro Hoberman, Judith M. Martin, Jeremy A. Hirota, Andrew C. Doxey and Nader Shaikh Tags: Research Source Type: research

High-dimensional analysis reveals an immune atlas and novel neutrophil clusters in the lungs of model animals with Actinobacillus pleuropneumoniae-induced pneumonia
AbstractDue to the increase in bacterial resistance, improving the anti-infectious immunity of the host is rapidly becoming a new strategy for the prevention and treatment of bacterial pneumonia. However, the specific lung immune responses and key immune cell subsets involved in bacterial infection are obscure.Actinobacillus pleuropneumoniae (APP) can cause porcine pleuropneumonia, a highly contagious respiratory disease that has caused severe economic losses in the swine industry. Here, using high-dimensional mass cytometry, the major immune cell repertoire in the lungs of mice with APP infection was profiled. Various phe...
Source: Veterinary Research - September 13, 2023 Category: Veterinary Research Source Type: research

Influenza viruses circulation in a tertiary care children hospital in Rome: a comparison between 2022 and the previous 5 years
ConclusionsWhen compared with pre SARS-CoV-2 pandemic years, our data show a significant increase in Influenza cases during weeks 18 –41/2022 and reveal an unexpected summer circulation of these viruses: just weeks 26–30 showed to be influenza virus free. A national year-round Flu surveillance could be useful to understand if changing in influenza epidemiology is transitional or likely to persist in the following years.
Source: Italian Journal of Pediatrics - September 13, 2023 Category: Pediatrics Source Type: research

C.D.C. Recommends New Covid Vaccines for All Americans
Everyone aged 6 months and older should get at least one dose, the agency said.
Source: NYT Health - September 12, 2023 Category: Consumer Health News Authors: Apoorva Mandavilli Tags: your-feed-science Drugs (Pharmaceuticals) Vaccination and Immunization Coronavirus (2019-nCoV) Influenza Centers for Disease Control and Prevention Moderna Inc Pfizer Inc Source Type: news

DHS Calls on Wisconsinites to Make a Plan to Protect Against Respiratory Illnesses This Fall
The Wisconsin Department of Health Services (DHS) is calling on Wisconsinites to make a plan to get vaccinated against respiratory illnesses this fall. The reminder comes as the updated COVID-19 vaccine has received federal regulatory approval, a new annual flu vaccine is available, and a vaccine and antibody to prevent respiratory syncytial virus (RSV) is on the market. With cooler temperatures, the risk of respiratory illnesses rises, but there are now more tools available to keep people...(see release)Elizabeth.GoodsittSeptember 12, 2023
Source: Wisconsin DHFS Press Releases - September 12, 2023 Category: Hospital Management Authors: Elizabeth.Goodsitt Source Type: news

C.D.C. Advisers Recommend New Covid Vaccines for All Americans
Everyone aged 6 months and older should get at least one dose, the panel said.
Source: NYT Health - September 12, 2023 Category: Consumer Health News Authors: Apoorva Mandavilli Tags: your-feed-science Drugs (Pharmaceuticals) Vaccination and Immunization Coronavirus (2019-nCoV) Influenza Centers for Disease Control and Prevention Moderna Inc Pfizer Inc Source Type: news

Decongestant in Cold Medicines Doesn ’t Work, Panel Says
The agency now must decide whether products containing the ingredient, like some Sudafed and NyQuil products, should no longer be sold.
Source: NYT Health - September 12, 2023 Category: Consumer Health News Authors: Christina Jewett Tags: Drugs (Pharmaceuticals) Colds Drugstores Influenza Food and Drug Administration Consumer Healthcare Products Assn your-feed-healthcare Source Type: news

Covid-19, flu, RSV: Here are the vaccine recommendations for fall
Here's what you should know about each vaccine as we prepare for a possible " tripledemic " this fall and winter. "The third is the RSV (respiratory syncytial virus) vaccine. It's the newest, in many ways, it's the most exciting because we haven't been able to do anything about protecting either…#rsv #pavia #andrewpavia #universityofutah #cdc #icu #omicron #fda #acip #medicare
Source: Reuters: Health - September 12, 2023 Category: Consumer Health News Source Type: news

Flu Vaccine Cut Hospitalizations In South America —Here’s What That Means For The U.S.
The vaccine reduced the risk of hospitalization by 52% in five different countries.
Source: Forbes.com Healthcare News - September 12, 2023 Category: Pharmaceuticals Authors: Arianna Johnson, Forbes Staff Tags: Innovation /innovation Healthcare /healthcare Breaking breaking-news Trending Explainer Trending-Explainer topline Source Type: news

Fury over 'chaotic' start to Covid and flu autumn jab rollouts: Pharmacies and GPs hit out at health chiefs as jab deliveries fail to show up
EXCLUSIVE: Industry leaders today slammed the 'chaotic decision making' by NHS England, with pharmacy teams reporting 'very patchy and disorganised' jab distribution.
Source: the Mail online | Health - September 12, 2023 Category: Consumer Health News Source Type: news

Should You Get the Flu Shot and COVID Booster at the Same Time?
(MedPage Today) -- An annual flu shot for all. An annual COVID shot for some. (Or many? Or most? Or all? We don't know just yet.) That seems to be where we are headed. While there's a reasonable debate about whether everyone needs an annual COVID...
Source: MedPage Today Public Health - September 12, 2023 Category: American Health Source Type: news

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