Clinical Outcomes of Hospitalized Patients with SARS-CoV-2 Omicron Variant vs. Influenza A During Influenza Season 2021 to 2022: A Retrospective Observational Study
CONCLUSIONS: Patients diagnosed with Omicron had higher mortality than patients diagnosed with seasonal influenza. This finding could be due to differences in co-morbidities, the virus pathogenicity, and host responses to infection.PMID:37698307
Source: The Israel Medical Association Journal - September 12, 2023 Category: General Medicine Authors: Alaa Atamna Evgeny Berkov Genady Drozdinsky Tzippy Shochat Haim Ben Zvi Noa Eliakim-Raz Jihad Bishara Avishay Elis Source Type: research

Is Treosulfan-Based Conditioning Attractive as a Reduced-Intensity Conditioning Regimen in Korea?
CONCLUSION: This study suggests that Treo/Flu conditioning may be an alternative to Bu/Flu regimen in elderly patients with high-risk who are not suitable for standard conditioning.PMID:37698206 | PMC:PMC10497350 | DOI:10.3346/jkms.2023.38.e281
Source: Journal of Korean Medical Science - September 12, 2023 Category: Biomedical Science Authors: Se Hyung Kim Young Sok Ji Jina Yun Seong Hyeok Choi Sung Hee Lim Chan Kyu Kim Seong Kyu Park Source Type: research

Clinical Outcomes of Hospitalized Patients with SARS-CoV-2 Omicron Variant vs. Influenza A During Influenza Season 2021 to 2022: A Retrospective Observational Study
CONCLUSIONS: Patients diagnosed with Omicron had higher mortality than patients diagnosed with seasonal influenza. This finding could be due to differences in co-morbidities, the virus pathogenicity, and host responses to infection.PMID:37698307
Source: The Israel Medical Association Journal - September 12, 2023 Category: General Medicine Authors: Alaa Atamna Evgeny Berkov Genady Drozdinsky Tzippy Shochat Haim Ben Zvi Noa Eliakim-Raz Jihad Bishara Avishay Elis Source Type: research

Is Treosulfan-Based Conditioning Attractive as a Reduced-Intensity Conditioning Regimen in Korea?
CONCLUSION: This study suggests that Treo/Flu conditioning may be an alternative to Bu/Flu regimen in elderly patients with high-risk who are not suitable for standard conditioning.PMID:37698206 | PMC:PMC10497350 | DOI:10.3346/jkms.2023.38.e281
Source: J Korean Med Sci - September 12, 2023 Category: General Medicine Authors: Se Hyung Kim Young Sok Ji Jina Yun Seong Hyeok Choi Sung Hee Lim Chan Kyu Kim Seong Kyu Park Source Type: research

Clinical Outcomes of Hospitalized Patients with SARS-CoV-2 Omicron Variant vs. Influenza A During Influenza Season 2021 to 2022: A Retrospective Observational Study
CONCLUSIONS: Patients diagnosed with Omicron had higher mortality than patients diagnosed with seasonal influenza. This finding could be due to differences in co-morbidities, the virus pathogenicity, and host responses to infection.PMID:37698307
Source: The Israel Medical Association Journal - September 12, 2023 Category: General Medicine Authors: Alaa Atamna Evgeny Berkov Genady Drozdinsky Tzippy Shochat Haim Ben Zvi Noa Eliakim-Raz Jihad Bishara Avishay Elis Source Type: research

DAYQUIL AND NYQUIL SEVERE PLUS VICKS VAPOCOOL COLD AND FLU (acetaminophen, phenylephrine hydrochloride, and doxylamine succinate) kit The Procter & Gamble Manufacturing Company
Updated Date: Tue, 12 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 12, 2023 Category: Drugs & Pharmacology Source Type: alerts

VICKS DAYQUIL AND VICKS NYQUIL COLD AND FLU (acetaminophen, dextromethorphan hydrobromide, phenylephrine hydrochloride, and doxylamine succinate) kit The Procter & Gamble Manufacturing Company
Updated Date: Tue, 12 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 12, 2023 Category: Drugs & Pharmacology Source Type: alerts

Comparative effectiveness of mRNA-1273 and BNT162b2 COVID-19 vaccines in immunocompromised individuals: a systematic review and meta-analysis using the GRADE framework
ConclusionThis GRADE meta-analysis based on a large number of consistent observational studies showed that the mRNA-1273 COVID-19 vaccine is associated with improved clinical effectiveness in IC populations compared with BNT162b2.
Source: Frontiers in Immunology - September 12, 2023 Category: Allergy & Immunology Source Type: research

Viruses, Vol. 15, Pages 1909: Different Outcomes of Chicken Infection with UK-Origin H5N1-2020 and H5N8-2020 High-Pathogenicity Avian Influenza Viruses (Clade 2.3.4.4b)
Marek J. Slomka Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) of the “goose/Guangdong” lineage have caused a series of European epizootics since 2014. During autumn/winter 2020–2021, several H5Nx subtypes were detected in the UK, with H5N8 being the dominant subtype in wild birds and poultry. Despite the greater subtype diversity (due to viral neuraminidase gene reassortment) reported in wild birds, only H5N8 and H5N1 subtypes caused clade 2.3.4.4 UK HPAIV poultry outbreaks during this period. The direct inoculation of layer chickens showed that H5N8-2...
Source: Viruses - September 12, 2023 Category: Virology Authors: Amanda H. Seekings Caroline J. Warren Saumya S. Thomas Fabian Z. X. Lean David Selden Benjamin C. Mollett Pauline M. van Diemen Ashley C. Banyard Marek J. Slomka Tags: Article Source Type: research

Potential for transmission of naturally mutated H10N1 avian influenza virus to mammalian hosts and causing severe pulmonary disease
Subtype H10 avian influenza viruses (AIV) are distributed worldwide in wild aquatic birds, and can infect humans and several other mammalian species. In the present study, we investigated the naturally mutated PB2 gene in A/aquatic bird/South Korea/SW1/2018 (A/SW1/18, H10N1), isolated from wild birds during the 2018–2019 winter season. This virus was originally found in South Korea, and is similar to isolates from mainland China and Mongolia. It had low pathogenicity, lacked a multi-basic cleavage site, and showed a binding preference for α2,3-linked sialic acids. However, it can infect mice, causing severe disease and ...
Source: Frontiers in Microbiology - September 12, 2023 Category: Microbiology Source Type: research

Flu advice in the U.S. news media changed during the COVID-19 pandemic but not the evidence
Source: European Journal of Epidemiology - September 12, 2023 Category: Epidemiology Source Type: research

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