Oral adverse events following COVID-19 and influenza vaccination in Australia
This study evaluates these AEs using the Australian Database of Adverse Event Notifications (DAEN). A secondary analysis of DAEN data was conducted, with the analysis period commencing from the start of the COVID-19 vaccination rollout in February 2021 and the inception of the influenza vaccine database in 1971, both through until December 2022. The focus of the analysis was on oral AEs related to COVID-19 and influenza vaccines. Reports were extracted according to a predefined schema and then stratified by vaccine type, sex, and age. Oral paresthesia was the most common oral AE after COVID-19 vaccination (75.28 per 10,000...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Abanoub Riad Julien Issa Sameh Attia Ladislav Du Å¡ek Miloslav Klugar Source Type: research

A CRISPR-Cas12a-based platform facilitates the detection and serotyping of Streptococcus suis serotype 2
In this study, we developed a high-fidelity detection and serotyping platform for S. suis serotype 2 based on recombinase polymerase amplification (RPA) and a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas12a system called Cards-SSJ/K. Cards-SSJ had a detection limit of 10 CFU, takes <60 min, and no cross-reaction was found with other S. suis serotypes, closely related Streptococcus spp., or common pig pathogens, and Cards-SSK could differentiate serotype 2 from serotype 1/2. Results from Cards-SSJ and qPCR were equivalent in detecting S. suis serotype 2 in tissue samples. Analysis indicated that ...
Source: Talanta - September 21, 2023 Category: Chemistry Authors: Lu Wang Jing Sun Jiyu Zhao Jieyu Bai Yueling Zhang Yao Zhu Wanjiang Zhang Chunlai Wang Paul R Langford Siguo Liu Gang Li Source Type: research

In Situ Spectroscopic Detection of Large-Scale Reorientations of Transmembrane Helices During Influenza A M2 Channel Opening
Angew Chem Int Ed Engl. 2023 Sep 21:e202309069. doi: 10.1002/anie.202309069. Online ahead of print.ABSTRACTViroporins are small ion channels in membranes of enveloped viruses that play key roles during viral life cycles. To use viroporins as drug targets against viral infection requires in-depth mechanistic understanding and, with that, methods that enable investigations under in situ conditions. Here, we apply surface-enhanced infrared absorption (SEIRA) spectroscopy to Influenza A M2 reconstituted within a solid-supported membrane, to shed light on the mechanics of its viroporin function. M2 is a paradigm of pH-activated...
Source: Angewandte Chemie - September 21, 2023 Category: Chemistry Authors: Ronja Rabea Paschke Swantje Mohr Sascha Lange Adam Lange Jacek Kozuch Source Type: research

Review: Factors influencing parents' decisions to vaccinate children against COVID-19
CONCLUSION: This review identified critical factors affecting parents' vaccination behavior for their children. Awareness of these factors may reduce parents' COVID-19 vaccine refusal for their children and guide future planning and development of public health studies.PMID:37735055 | DOI:10.1016/j.vaccine.2023.09.020
Source: Vaccine - September 21, 2023 Category: Allergy & Immunology Authors: Haifa S Alharbi Source Type: research

Identification of γ-Fagarine as a novel antiviral agent against respiratory virus (hMPV) infection
In this study, we aim to investigate the effect of γ-Fagarine on hMPV infection and explore its underlying molecular mechanisms. Vero-E6 and 16HBE cells were used as cell models. Virus replication and microcosm character were explored in Vero-E6 cells. Then, the antiviral activities were investigated by quantitative real-time PCR (RT-qPCR), western blotting (WB), and indirect immunofluorescence assays (IFAs) in Vero-E6 and 16HBE. Potential mechanisms of γ-Fagarine related to HSPG and lysosome pH were assessed in 16HBE cells. Lastly, a virus-infected mouse model was established and antiviral assay in vivo was conducted. Î...
Source: Virus Research - September 21, 2023 Category: Virology Authors: Jinhua Li Yao Zhao Ying Dai Junning Zhao Source Type: research

GSE243629 A single-cell atlas of the peripheral immune response in patients with influenza A virus infection
Contributors : Yin Zhang ; Lu Zong ; Ying Huang ; Yuanhong XuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensInfluenza A virus (IAV) continues to be a critical global health problem, especially for vulnerable populations such as children and pregnant women. While certain circulating cell subsets are thought to differentially modulate the immune response to IAV infection, the nature and function of these subsets is unclear. Our findings provide a comprehensive understanding of the cellular subtypes and molecular characteristics of PBMCs across different populations with IAV infection. ...
Source: GEO: Gene Expression Omnibus - September 21, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Student's 'freshers' flu' turned out to be meningitis
A student who ignored the symptoms of meningitis urges others to be aware of the signs.
Source: BBC News | Health | UK Edition - September 21, 2023 Category: Consumer Health News Source Type: news

COLD AND FLU DAYTIME SEVERE, 24/7 LIFE (acetaminophen, dextromethorphan hbr, guaifenesin, phenylephrine hcl tablet) tablet, film coated Lil' Drug Store Products, Inc.
Updated Date: Thu, 21 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 21, 2023 Category: Drugs & Pharmacology Source Type: alerts

Effects of Message Framing and Narrative Format on Promoting Persuasive Conversations with Others About the Flu Vaccine
.
Source: Health Communication - September 21, 2023 Category: Health Management Authors: Nehama LewisErga Atada Department of Communication, University of Haifab Lauder School of Government, Diplomacy and Strategy, Reichman University Source Type: research

Recovery of Extracorporeal Lungs Using Cross-Circulation with Injured Recipient Swine
Lung transplantation remains limited by the shortage of healthy organs. Cross-circulation with a healthy swine recipient provides a durable physiologic environment to recover injured donor lungs. In a clinical application, a recipient awaiting lung transplantation could be placed on cross-circulation to recover damaged donor lungs, enabling eventual transplantation. Our objective was to assess the ability of recipient swine with respiratory compromise to tolerate cross-circulation and support recovery of donor lungs subjected to extended cold ischemia.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Panpan Chen, Julie Van Hassel, Meghan R. Pinezich, Mohamed Diane, Maria R. Hudock, Sarah R. Kaslow, Olimpia P. Gavaudan, Kenmond Fung, Mandy L. Kain, Hermogenes Lopez, Anjali Saqi, Brandon A. Guenthart, Ahmed E. Hozain, Alexander Romanov, Matthew Bacchett Source Type: research

Oral adverse events following COVID-19 and influenza vaccination in Australia
Volume 19, Issue 2, August 2023 .
Source: Human Vaccines and Immunotherapeutics - September 21, 2023 Category: Allergy & Immunology Authors: Abanoub RiadJulien IssaSameh AttiaLadislav Du Å¡ekMiloslav Klugara Institute of Health Information and Statistics of the Czech Republic (IHIS-CR), Prague, Czech Republicb Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochr Source Type: research

Population structure and genetic diversity of Streptococcus suis isolates obtained from the United States
This study applied whole genome sequencing and cgMLST-based typing to evaluate the population structure and genetic relatedness among S. suis isolates obtained within the U.S. The established high-resolution phylogenomic framework revealed extensive genomic variation and diversity among the sampled S. suis isolates, with isolates from the U.S. and from countries outside the U.S. found interspersed in the phylogeny. S. suis isolates obtained within the U.S. did not cluster by state or geographic location, however, isolates with similar serotypes, both obtained from within and outside the U.S., generally clustered together. ...
Source: Frontiers in Microbiology - September 21, 2023 Category: Microbiology Source Type: research

Challenges to delivering evidence-based management for long COVID
Early on in the COVID-19 pandemic, scientists forewarned of a potential medium to long-term post-acute sequelae in patients infected with SARS-CoV-2, similar to that documented in bacterial,1 protozoan and viral infections including Epstein-Barr virus,2 Ebola virus,3 dengue virus,4 Chikunguña virus,5 going far back to the influenza pandemic in 1918.6 These varied symptoms following acute SARS-CoV-2 infection is now termed as long COVID and is also known as long-haulers syndrome, post COVID-19 condition (PCC),7 ‘post-acute sequelae of SARS-CoV-2 infection (PASC)’,7 ‘chronic COVID’ and many oth...
Source: Evidence-Based Medicine - September 21, 2023 Category: Internal Medicine Authors: Peiris, S., Izcovich, A., Ordunez, P., Luciani, S., Martinez, C., Aldighieri, S., Reveiz, L. Tags: Open access, COVID-19 Analysis Source Type: research

Untap Health wants to help offices and care homes track risk from bugs like flu and COVID-19
Ever since the pandemic we’ve been told we’ll need to learn to live with COVID-19, while also being warned it won’t be the last pandemic to hit us. Yet health risks aren’t equal in their impacts, so finding ways to intelligently manage risks around illness and infectious disease is critical work.…#untaphealth #disruptsfbattlefield #healthsafety #untap #clairetrant #jaybullen #entrepreneurfirst #phd #trant #dfid
Source: Reuters: Health - September 20, 2023 Category: Consumer Health News Source Type: news

Pages: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20