Sensors, Vol. 23, Pages 8000: Development and Analytical Evaluation of a Point-of-Care Electrochemical Biosensor for Rapid and Accurate SARS-CoV-2 Detection
In this study, we present an electrochemical biosensor that offers nearly instantaneous and precise SARS-CoV-2 detection, suitable for point-of-care and environmental monitoring applications. The biosensor employs a stapled hACE-2 N-terminal alpha helix peptide to functionalize an in situ grown polypyrrole conductive polymer on a nitrocellulose membrane backbone through a chemical process. We assessed the biosensor’s analytical performance using heat-inactivated omicron and delta variants of the SARS-CoV-2 virus in artificial saliva (AS) and nasal swab (NS) samples diluted in a strong ionic solution, as well ...
Source: Sensors - September 20, 2023 Category: Biotechnology Authors: Mesfin Meshesha Anik Sardar Ruchi Supekar Lopamudra Bhattacharjee Soumyo Chatterjee Nyancy Halder Kallol Mohanta Tarun Kanti Bhattacharyya Biplab Pal Tags: Article Source Type: research

Viruses, Vol. 15, Pages 1966: Isolation and Characterization of a Novel Recombinant Classical Pseudorabies Virus in the Context of the Variant Strains Pandemic in China
This study provided some valuable information for the study of the evolution of PRV in China.
Source: Viruses - September 20, 2023 Category: Virology Authors: Lian Liu Zhu Sun Yu Deng Li Li Tian Tags: Article Source Type: research

Viruses, Vol. 15, Pages 1961: The Antiviral Factor SERINC5 Impairs the Expression of Non-Self-DNA
th Serra-Moreno SERINC5 is a restriction factor that becomes incorporated into nascent retroviral particles, impairing their ability to infect target cells. In turn, retroviruses have evolved countermeasures against SERINC5. For instance, the primate lentiviruses (HIV and SIV) use Nef, Moloney Murine Leukemia Virus (MLV) uses GlycoGag, and Equine Infectious Anemia Virus (EIAV) uses S2 to remove SERINC5 from the plasma membrane, preventing its incorporation into progeny virions. Recent studies have shown that SERINC5 also restricts other viruses, such as Hepatitis B Virus (HBV) and Classical Swine Fever Virus (CSFV), al...
Source: Viruses - September 20, 2023 Category: Virology Authors: Yuhang Shi Sydney Simpson Shahad K. Ahmed Yuexuan Chen Aidin Tavakoli-Tameh Sanath Kumar Janaka David T. Evans Ruth Serra-Moreno Tags: Article Source Type: research

Variables influencing the prediction of fluid responsiveness: a systematic review and meta-analysis
Prediction of fluid responsiveness in acutely ill patients might be influenced by a number of clinical and technical factors. We aim to identify variables potentially modifying the operative performance of flu...
Source: Critical Care - September 20, 2023 Category: Intensive Care Authors: Jorge Iv án Alvarado Sánchez, Juan Daniel Caicedo Ruiz, Juan José Diaztagle Fernández, Luís Eduardo Cruz Martínez, Fredy Leonardo Carreño Hernández, Carlos Andrés Santacruz Herrera and Gustavo Adolfo Ospina-Tascón Tags: Research Source Type: research

Ask Me Anything with IHS: Flu, RSV, COVID
Sep 28, 2023. . Sponsored by National Indian Health Board
Source: Rural events via the Rural Assistance Center - September 19, 2023 Category: Rural Health Source Type: events

One common virus is still killing thousands of children every year – but new vaccines offer hope | Devi Sridhar
Exciting scientific developments offer solutions to respiratory syncytial virus (RSV). The only barrier is costThe number one cause of infants being hospitalised in the US and Europe is a virus you ’ve probably never heard of:RSV. Most people experience it as a mild infection resembling a cold. But it can be very serious in babies and elderly people. The tell-tale symptoms are abnormally fast breathing, a caving-in of the chest between and under the ribs, and wheezing or crackles – worrying noises caused by the bronchial tubes being inflamed, or the small air sacs in the lungs filling with fluid. The virus makes it har...
Source: Guardian Unlimited Science - September 19, 2023 Category: Science Authors: Devi Sridhar Tags: Vaccines and immunisation Science Health Drugs Children Infant and child mortality Source Type: news

Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research

Geospatial Distribution of Racial Disparities in Influenza Vaccination in Nursing Homes
This study aimed to assess the distribution of racial disparities in influenza vaccination between White and Black short-stay and long-stay nursing home residents among states and hospital referral regions (HRRs).
Source: Journal of the American Medical Directors Association - September 19, 2023 Category: Health Management Authors: Joe B.B. Silva, Chanelle J. Howe, John W. Jackson, Barbara H. Bardenheier, Melissa R. Riester, Robertus van Aalst, Matthew M. Loiacono, Andrew R. Zullo Tags: Original Study Source Type: research

Editorial Note: School-Located Influenza Vaccination Reduces Community Risk for Influenza and Influenza-Like Illness Emergency Care Visits
by The PLOS ONE Editors
Source: PLoS One - September 19, 2023 Category: Biomedical Science Authors: The PLOS ONE Editors Source Type: research

Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
In the course of the SARS-CoV-2 pandemic, multiple vaccines were developed. Little was known about reactogenicity and safety in comparison to established vaccines, e.g. influenza, pneumococcus, or herpes zoste...
Source: BMC Medicine - September 19, 2023 Category: Internal Medicine Authors: Felix Werner, Nikoletta Zeschick, Thomas K ühlein, Philipp Steininger, Klaus Überla, Isabelle Kaiser, Maria Sebastião, Susann Hueber and Lisette Warkentin Tags: Research article Source Type: research

Moderna, Pfizer Stocks Fall With Weak Expected Covid Vaccine Demand
Shares of vaccine makers moved lower Monday after Pfizer's finance chief predicted weaker demand for Covid shots this year. Pfizer CFO David Denton said his company projects a roughly 24% Covid vaccination rate in the U.S. this year. "Keep in mind the flu is probably closer to a 50% vaccination…#pfizer #pfizercfo #daviddenton #jpmorgan
Source: Reuters: Health - September 18, 2023 Category: Consumer Health News Source Type: news

NIH Begins Human Trials of ' Universal ' Flu Vaccine NIH Begins Human Trials of ' Universal ' Flu Vaccine
The National Institutes of Health has begun an early stage study on its experimental vaccine targeting six strains of influenza virus.Reuters Health Information
Source: Medscape Medical News Headlines - September 18, 2023 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Agaricus Bisporus and Influenza Vaccination Response
Condition:   Immune Response Interventions:   Biological: Influenza vaccine;   Dietary Supplement: Agaricus bisporus capsules;   Dietary Supplement: Control capsules Sponsors:   Maastricht University Medical Center;   Scelta Mycofriends B.V.;   CNC Grondstoffen B.V. Not yet recruiting
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

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