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Fight Aging! Newsletter, April 13th 2020
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training.
From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - April 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Businesses Combat Covid ‐19
Chris EdwardsThe economics news is dismal with reports every day of shutdowns, layoffs, and furloughs. More than 16 million Americans have been thrown out of work so far, and we have entered the worst downturn since the Great Depression of the 1930s.Yet amid the gloom there are frequent reports of businesses and entrepreneurs making advances in the battle against Covid ‐19. The private sector is racing to produce vaccines, treatments, tests, and medical supplies to defeat the pandemic.Here are some recent developments:Formlabs ischurning out Covid ‐19 test swabs with 3‑D printing, going from prototype to produc...
Source: Cato-at-liberty - April 10, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs
Businesses Combat COVID-19
Chris EdwardsThe economics news is dismal with reports every day of shutdowns, layoffs, and furloughs. More than 16 million Americans have been thrown out of work so far, and we have entered the worst downturn since the Great Depression of the 1930s.Yet amid the gloom there are frequent reports of businesses and entrepreneurs making advances in the battle against Covid ‐19. The private sector is racing to produce vaccines, treatments, tests, and medical supplies to defeat the pandemic.Here are some recent developments:Formlabs ischurning out COVID-19 test swabs with 3-D printing, going from prototype to production in ...
Source: Cato-at-liberty - April 10, 2020 Category: American Health Authors: Chris Edwards Source Type: blogs
Rejuvenation of Immune Function is One of the More Important Outcomes to Engineer through the Treatment of Aging
One would hope that it does not require an ongoing pandemic and related hysteria to point out that old people have poorly functioning immune systems, and thus suffer disproportionately the burden of infectious disease. But perhaps it does. The 2017-2018 seasonal influenza, a modestly more severe occurrence of something that happens every year, killed something like 60,000 people in the US alone, with little notice or comment. There is nothing so terrible that it won't be accepted - ignored, even - if it is normal.
Floodgates of funding for infectious disease research and development have been opened in response to C...
Source: Fight Aging! - April 6, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Thought experiment
Please don ' t get me wrong. I ' ve seen other people try to put our present crisis in context, or discuss the costs vs. the benefits of certain actions, and be widely condemned for insensitivity or even sociopathy. I remember after the 9/11 attack, when people who tried to explain the motivations or sociological origins of Al Qaeda and similar movements faced the same sort of criticism. You weren ' t allowed to think about the problem, people weren ' t ready for any sort of moral confusion. In what I am about to say, I am not arguing against saving lives, on the contrary. I ' m just trying to explain something about where...
Source: Stayin' Alive - April 1, 2020 Category: American Health Source Type: blogs
Is it safe to see the pediatrician for vaccines and medical visits?
We’re tackling a few urgent questions from parents in this time of coronavirus and COVID-19. Are you wondering if babies and children should continue to have vaccines on schedule? Thinking about how to manage regular medical appointments, and which situations require in-person visits to a pediatric practice? Read on.
Should parents take babies for initial vaccines right now? What about toddlers and older children who are due for vaccines?
The answer to this question is going to depend on many factors, including what your doctor’s office is offering. As with all health care decisions, it comes down to weighing risks and...
Source: Harvard Health Blog - March 31, 2020 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Children's Health Health care Parenting Vaccines Source Type: blogs
OK, boomer: You ’re not the only one who needs testing for hepatitis C
It turns out that many more people than just boomers can benefit from testing for hepatitis C, a viral infection of the liver that often causes no symptoms. If you’re a member of the baby-boom generation (born between 1946 and 1964), your doctor may have already recommended the test. But those born before or after those years may not have known about the test unless they had a risk factor for hepatitis C, such as a history of intravenous drug use. A new guideline is changing this approach.
Why the different recommendations for baby boomers?
In 2012–2013, the CDC and the US Preventive Services Task Force (USPSTF) establ...
Source: Harvard Health Blog - March 31, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Digestive Disorders Health Infectious diseases Men's Health Sexual Conditions Women's Health Source Type: blogs
Time to Move on the Economy vs. Public Health Debate
Ryan BourneHuman life is highly valuable. Basic economic reasoning therefore suggests that, given the risks of COVID-19 to vulnerable populations, we should be willing to withstand large economic costs to prevent the risk of substantial numbers of deaths. This is particularly true if most of those economic costs are temporary.In response to Donald Trump ’stweet last week suggesting “WE CANNOT LET THE CURE BE WORSE THAN THE PROBLEM ITSELF,”many economists have indeed been makingthese points.They highlight estimates suggesting that the estimated value of a statistical life (commonly around $9.3 million) and a ...
Source: Cato-at-liberty - March 27, 2020 Category: American Health Authors: Ryan Bourne Source Type: blogs
Top Ten Ways I've Survived Social Distancing
Sequestered away and worried about COVID–19? It ’s good to take this crisis seriously, but social distancing doesn’t have to be as dire as people online make it seem. Here are the top ten ways I’ve kept my attitude upbeat while isolated from others.As I’ve written before, I’ve been sick and social distancing since September 2019. I have asthmatic bronchitis, rhinitis, and chronic respiratory inflammation. Consequently, my body has been so busy struggling to breathe, it hasn’t had much oomph left to fight off every cold& virus in Utah. At first, I just thought I was getting a lot of colds f...
Source: The Splintered Mind by Douglas Cootey - March 19, 2020 Category: Psychiatry Tags: Depression Family Goodreads Journaling Source Type: blogs
Top Ten Ways I ' ve Survived Social Distancing
Sequestered away and worried about COVID–19? It ’s good to take this crisis seriously, but social distancing doesn’t have to be as dire as people online make it seem. Here are the top ten ways I’ve kept my attitude upbeat while isolated from others.As I’ve written before, I’ve been sick and social distancing since September 2019. I have asthmatic bronchitis, rhinitis, and chronic respiratory inflammation. Consequently, my body has been so busy struggling to breathe, it hasn’t had much oomph left to fight off every cold& virus in Utah. At first, I just thought I was getting a lot of colds f...
Source: The Splintered Mind by Douglas Cootey - March 19, 2020 Category: Psychiatry Tags: Depression Family Goodreads Journaling Source Type: blogs
Reasons to chill and reasons not to chill
Okay, I ' m not an epidemiologist or a virologist. But I do know something about those subjects, I ' m a public health professor, and I am an expert in clinical communication and risk communication. So I ' m going to offer some observations that I hope will help people keep this public health scare in proper perspective and maybe be of practical use.There are two important parameters we need to understand the risk caused by any communicable disease. I ' m going to broadly say transmissibility, and the probability that exposure will lead to serious disease.We often see transmissibility represented as a single number, called...
Source: Stayin' Alive - February 26, 2020 Category: American Health Source Type: blogs
Fight Aging! Newsletter, February 24th 2020
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve.
A Comparison of Biological Age Measurement Approaches
https://www.fightaging.org/archives/2020/02/a-comparison-of-biological-age-measurement-approaches/
Researchers here assess the performance of a range of approaches to measuring biological...
Source: Fight Aging! - February 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Interview with Lewis Gruber of SIWA Therapeutics
SIWA Therapeutics is one of the few senolytics biotech companies founded prior to the past few years, invigorated with new funding now that the clearance of senescent cells as a basis for rejuvenation is an area of intense interest for the research and development community. The company is also, I believe, running the only senolytics program based the use of monoclonal antibodies. This is a way to encourage the immune system to destroy cells bearing specific surface markers, in this case a form of advanced glycation endproduct that is found on cancerous, senescent, and otherwise dysfunctional cells.
Many of our re...
Source: Fight Aging! - February 19, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, February 17th 2020
Discussion of the Evolutionary Genetics of Aging
Thymic Involution Contributes to Immunosenescence and Inflammaging
The Potential for Exosome Therapies to Treat Sarcopenia
Correlations of Mitochondrial DNA Copy Number and Epigenetic Age Measures
Evidence for PASK Deficiency to Reduce the Impact of Aging in Mice
The Aging Retina, a Mirror of the Aging Brain
Evidence for Loss of Capillary Density to be Important in Heart Disease
Aspects of Immune System Aging Proceed More Rapidly in Men
Deacetylation of the NLRP3 Inflammasome as a Way to Control Chronic Inflammation
Transplantation of Senescent Cells is an ...
Source: Fight Aging! - February 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Podcast: Managing Coronavirus Outbreak Anxiety
Does the new coronavirus from China make you a little anxious? How concerned should we be? Is it a real threat or mostly hype? In today’s podcast, Dr. John Grohol, founder and editor-in-chief of PsychCentral.com, explains what the coronavirus is, how it compares to the flu and why it seems to have hit the panic button in a lot of people. He offers tips to avoid getting sick in general, and importantly, gives advice on how to keep our anxiety levels in check when it comes to new disease outbreaks, especially in how we seek information from the media.
If you’d like to learn more about the coronavirus and how to deal wi...
Source: World of Psychology - February 13, 2020 Category: Psychiatry & Psychology Authors: The Psych Central Podcast Tags: Anxiety and Panic Disorders General Health-related Interview Podcast The Psych Central Show Source Type: blogs
