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I ’m grateful for your trust in me. I wish it didn’t require a cancer diagnosis to win it.
You are my favorite patient. You’re charming and funny. You proudly tell me you’ve just retired – having built multiple successful businesses from scratch. You were admitted to my service with rapidly progressive respiratory failure. Your CT shows cancer everywhere. You are the same age as my husband.“I’m not getting that vaccine. It’s myRead more …I’m grateful for your trust in me. I wish it didn’t require a cancer diagnosis to win it. originally appeared inKevinMD.com.
Source: Kevin, M.D. - Medical Weblog - October 2, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/cynthia-cooper" rel="tag" > Cynthia Cooper, MD < /a > < /span > Tags: Physician COVID-19 coronavirus Hospital-Based Medicine Infectious Disease Oncology/Hematology Source Type: blogs

Chronic Kidney Disease and an Accelerated Aging of the Immune System
In conclusion, premature thymic involution and chronic inflammation greatly contribute to increased morbidity and mortality in CKD patients. Mechanisms are likely to be multiple and interlinked. Even when the quest to fountain of youth is a pipe dream, there are many scientific opportunities to prevent or to, at least in part, reverse CKD-related immune senescence. Further studies should precisely define most important pathways driving premature immune ageing in CKD patients and best therapeutic options to control them.
Source: Fight Aging! - September 29, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Towards Better Cancer Vaccines via Identification of Important Neoantigens and T Cell Populations
Tumor cells have identifying surface markers that the immune system can in principle attack, but vaccination against those surface markers in order to encourage an anti-tumor immune response has been hit and miss. Researchers here dig deeper into the mechanisms that may explain this variability in response, and thus allow a more viable approach to patient-specific cancer vaccines that will more effectively rouse the immune system to target cancerous cells. When cells begin to turn cancerous, they start producing mutated proteins not seen in healthy cells. These cancerous proteins, also called neoantigens, can aler...
Source: Fight Aging! - September 28, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

An urgent message
I get a lot of strange e-mails, but every once in a while something comes across Your Intertubes that is essential reading. This cannot be ignored.experts and scholars:     The content in the attachment is provided to you by the dean of the World Academy of Sciences, superpowered scientists, the final review member of the Prophet International Union Cult Appraisal Committee ,The double-edged sword in Revelation Bible prophecy --- King Kong Prophet Su Bei Jian, and the Prophet International Union Including " The main reason for global abnormal natural disasters " , " Floods caused by rapid de...
Source: Stayin' Alive - September 10, 2021 Category: American Health Source Type: blogs

Cancer
I sometimes like to open my posts with a joke. But not this time. There isn ' t a joke for this.Mrs. Dalai has cancer.How ' s that for a kick in the ass? I am neither vain nor arrogant enough to think that I could write the ultimate treatise on dealing with a loved one ' s cancer. There are any number of engaging stories out there on Caring Bridge and the like. You don ' t want to read a tear-jerker anyway, nor do you want to endure every last boring and/or gory detail. Mrs. Dalai would be very upset with me if I shared all that. Hell, she ' s probably going to be upset with me for writing this at all. She is a very p...
Source: Dalai's PACS Blog - September 4, 2021 Category: Radiology Source Type: blogs

Sleepless Nights For Evolutionary Biologists: A Greek Tragedy in The Making
By MIKE MAGEE In my Jesuit high school, we were offered only one science course – chemistry. I took it in my Senior year and did pretty well. In contrast, I took four years of Latin, and three years of Greek, as part of the school’s Greek Honors tract. Little did I know that Covid would create a pathologic convergence of sorts six decades later. Let’s review the Covid mutants: Alpha – A variant first detected in Kent, UK with 50% more transmissibility than the original and has spread widely. Beta – Originating in South Africa and the first to show a mutation that partially provided evas...
Source: The Health Care Blog - August 30, 2021 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy evolutionary biology Mike Magee Source Type: blogs

Fight Aging! Newsletter, August 30th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out mo...
Source: Fight Aging! - August 29, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Mindfulness Can Help Us Overcome Our Deepest Fears
Mindfulness is all the rage for multiple reasons. This practice helps you halt future fears and ruminations about an immutable past and live in the present moment. That isn’t the only benefit you can reap, however. Mindfulness allows you to capture what neurologist and Holocaust survivor Victor Frankl describes as freedom — the pause between an external stimulus and your reaction to it. Here’s how you can use this practice to help you overcome your deepest fears. 1. It Helps With Health Procedures Do you feel nervous before you go to the dentist? If so, you aren’t alone. Approximately a third of the popula...
Source: PickTheBrain | Motivation and Self Improvement - August 23, 2021 Category: Consumer Health News Authors: Kara Reynolds Tags: confidence depression featured happiness meditation psychology self-improvement fear mindfulness self improvement success Source Type: blogs

George Halvorson HIMSS Changemaker Lifetime Achievement Award Acceptance Speech, Part 2
Former Kaiser Permanente CEO George Halvorson has written on THCB on and off over the years, most notably last year with his proposal for Medicare Advantage for All post-COVID. This month he was given a lifetime achievement award by HIMSS and we are running his acceptance speech in two parts. We ran part one last week, and here’s part two– Matthew Holt We also initially have an important and continuously improving sense of the epigenetic processes that exist in all of us to develop our own responses to the world we are in at a biological level, and we should be able to use that information to improve ou...
Source: The Health Care Blog - August 23, 2021 Category: Consumer Health News Authors: matthew holt Tags: Health Tech Health Technology Early Childhood Education George Halvorson HIMSS Changemaker Lifetime Achievement Award payment models Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Immune System Should be a High Priority Target in the Development of Rejuvenation Therapies
The immune system has many roles. It doesn't just destroy invading pathogens, but also hunts and kills potentially harmful cells, such as those that have become senescent or potentially cancerous. Further, immune cells are intricately involved in the processes of tissue maintenance. Regeneration from injury is a complicated dance of signals and changed states carried out between stem cells, immune cells, and somatic cells. In the central nervous system, immune cells take on additional responsibilities related to maintaining and changing synaptic connections between neurons. The immune system fails with age. Its fail...
Source: Fight Aging! - August 19, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Yes, Shit
By KIM BELLARD The Conversation had a provocative article by Stanford professor Richard White about how America has a bad pattern of wasting infrastructure spending.  In light of the surprisingly bipartisan $1 trillion infrastructure bill recently passed by the Senate, this seems like something we should be giving some serious thought to.  I’ll posit that we’re doing it again, by not adequately addressing the potential that our excreta, to be polite, offers to detect health issues, including but not limited to COVID-19.  No shit: excrement can be an important tool in public — and personal ...
Source: The Health Care Blog - August 17, 2021 Category: Consumer Health News Authors: Christina Liu Tags: Health Tech Kim Bellard public health wastewater monitoring Source Type: blogs

Fight Aging! Newsletter, August 16th 2021
In conclusion, cancer survivors, especially older individuals, demonstrate greater odds of and accelerated functional decline, suggesting that cancer and/or its treatment may alter aging trajectories. Linking Particulate Air Pollution and Dementia in a Small Region of the US https://www.fightaging.org/archives/2021/08/linking-particulate-air-pollution-and-dementia-in-a-small-region-of-the-us/ It is fairly settled that evident particulate air pollution, such as daily exposure to smoke from wood-fueled cooking fires, has a strongly detrimental effect on long-term health. The mechanisms involved are inflamm...
Source: Fight Aging! - August 15, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

We Live in an Age of Biotechnology, In Which We Could Choose to End the Suffering of Aging
Bringing degenerative aging under medical control, ending the tens of millions of deaths each year, ending the suffering of hundreds of millions more. This is a plausible goal for our era of biotechnology. Yet even as the first rejuvenation therapies have become a reality, in the form of first generation senolytic drugs that clear a sizable fraction of senescent cells from the body, there is little public enthusiasm for - and understanding of - the path ahead to a better world. A world in which people have the choice not to decay in body and mind as they gather wisdom and experience in later life. Change is in the air, but...
Source: Fight Aging! - August 10, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

IBM ’ s Moonshot Ambition In Healthcare
This article is a part of our series Tech Giants In Healthcare. Previous titles included Amazon’s Dive Into Healthcare: A 2021 UpdateIs Apple Going Into Healthcare?Google’s Masterplan for HealthcareMicrosoft Makes a 16-billion Dollar Bet On Healthcare Take a deeper dive into what these companies aim for in medicine with our e-book, Tech Giants In Healthcare. Back in 2015, IBM’s previous CEO, Virginia Rometty famously said that IBM’s “moon shot will be the impact we have on healthcare.” Under the Watson Health banner, the tech company has been leveraging its expertise in cognitive computing to a...
Source: The Medical Futurist - August 9, 2021 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Digital Health Research Future of Medicine Future of Pharma Health Sensors & Trackers Healthcare Design Personalized Medicine Portable Medical Diagnostics IBM ibm watson xprize A.I. quantum compu Source Type: blogs