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A Systematic Review of Implementation Research on Determinants and Strategies of Effective HIV Interventions for Men Who Have Sex with Men in the United States
Annu Rev Psychol. 2023 Sep 18. doi: 10.1146/annurev-psych-032620-035725. Online ahead of print.ABSTRACTMen who have sex with men (MSM) are disproportionately affected by HIV, accounting for two-thirds of HIV cases in the United States despite representing ∼5% of the adult population. Delivery and use of existing and highly effective HIV prevention and treatment strategies remain suboptimal among MSM. To summarize the state of the science, we systematically review implementation determinants and strategies of HIV-related health interventions using implementation science frameworks. Research on implementation barriers has ...
Source: Annual Review of Psychology - September 18, 2023 Category: Psychiatry & Psychology Authors: Brian Mustanski Artur Queiroz James Merle Alithia Zamantakis Juan Pablo Zapata Dennis H Li Nanette Benbow Maria Pyra Justin D Smith Source Type: research

Impact of Remimazolam versus Sevoflurane Anesthesia on Cerebral Oxygenation and Intracranial Pressure during Gynecological Laparoscopy with Mild Hypercapnia
CONCLUSIONS Remimazolam can provide a favorable hemodynamic profile and attenuate the increase in ONSD during gynecological laparoscopy compared with sevoflurane anesthesia during lung-protective ventilation with mild hypercapnia. Remimazolam can provide faster and better postoperative recovery than sevoflurane anesthesia.PMID:37717140 | DOI:10.12659/MSM.941315
Source: Medical Science Monitor - September 17, 2023 Category: Research Authors: Chun Gon Park Dongchul Lee Wol Seon Jung Dong Seop Kim Youn Yi Jo Hyun Jeong Kwak Source Type: research

A Review of the Role of Tendon Stem Cells in Tendon-Bone Regeneration
Med Sci Monit. 2023 Sep 16;29:e940805. doi: 10.12659/MSM.940805.ABSTRACTTendon-bone injuries are a prevalent health concern associated with sports and other physically demanding activities. These injuries have a limited innate healing ability, often leading to the formation of scar tissue rather than the regeneration of healthy tendon tissue. This scar tissue results from excessive fibrosis during the early healing process and often leads to reduced tendon function and an increased risk of reinjury. Traditionally, surgical reconstruction has been the primary treatment for tendon-bone injuries. However, restoring the natura...
Source: Medical Science Monitor - September 16, 2023 Category: Research Authors: Junjie Chen Chuanfeng Jiang Lu Yin Yingqi Liu Yue He Sen Li Huarui Shen Source Type: research

Helicopter Ambulance Transport to the Emergency Department: Demographic and Clinical Factors Impacting Outcomes in a Turkish Medical Center
CONCLUSIONS Most patients transferred by HA had severe disease. ED physicians dealing with patient transfer by HAs should be prepared for severe cases, both in the HA and in the ED. HAs may be preferred when making the transfer decision for elderly patients, trauma patients, and those with cardiac disease.PMID:37710952 | DOI:10.12659/MSM.941464
Source: Medical Science Monitor - September 15, 2023 Category: Research Authors: Habibe Selmin Özensoy Selahattin G ürü Source Type: research

Evolution of HIV virulence in response to disease-modifying vaccines: A modeling study
Vaccine. 2023 Sep 13:S0264-410X(23)01027-7. doi: 10.1016/j.vaccine.2023.08.071. Online ahead of print.ABSTRACTPathogens face a tradeoff with respect to virulence; while more virulent strains often have higher per-contact transmission rates, they are also more likely to kill their hosts earlier. Because virulence is a heritable trait, there is concern that a disease-modifying vaccine, which reduces the disease severity of an infected vaccinee without changing the underlying pathogen genotype, may result in the evolution of higher pathogen virulence. We explored the potential for such virulence evolution with a disease-modif...
Source: Vaccine - September 15, 2023 Category: Allergy & Immunology Authors: Molly C Reid John E Mittler James T Murphy Sarah E Stansfield Steven M Goodreau Neil Abernethy Joshua T Herbeck Source Type: research

Predicting Survival Outcomes in Post-Cardiac Arrest Syndrome: The Impact of Combined Sequential Organ Failure Assessment Score and Serum Lactate Measurement
CONCLUSIONS Because of the superiority of the combined model of SOFA score and serum lactate level, combining these 2 factors could improve prediction of prognosis and survival outcomes in PCAS.PMID:37705234 | DOI:10.12659/MSM.942119
Source: Medical Science Monitor - September 14, 2023 Category: Research Authors: SooHyun Kim HeeWon Yang BangShill Rhee Hakyoon Song HyukHoon Kim Source Type: research

Cryo-EM captures a unique conformational rearrangement in 23S rRNA helices of the Mycobacterium 50S subunit
Int J Biol Macromol. 2023 Sep 12:126876. doi: 10.1016/j.ijbiomac.2023.126876. Online ahead of print.ABSTRACTStructural investigations of the ribosomes isolated from pathogenic and non-pathogenic Mycobacterium species have identified several mycobacteria-specific structural features of ribosomal RNA and proteins. Here, we report structural evidence of a hitherto unknown conformational switch of mycobacterium 23S rRNA helices (H54a and H67-H71). Cryo-electron microscopy (cryo-EM) structures (~3-4 Å) of the M. smegmatis (Msm) log-phase 50S ribosomal subunit revealed conformational variability in H67-H71 region of the 23S rRN...
Source: International Journal of Biological Macromolecules - September 14, 2023 Category: Biochemistry Authors: Priya Baid Jayati Sengupta Source Type: research

Predicting Survival Outcomes in Post-Cardiac Arrest Syndrome: The Impact of Combined Sequential Organ Failure Assessment Score and Serum Lactate Measurement
CONCLUSIONS Because of the superiority of the combined model of SOFA score and serum lactate level, combining these 2 factors could improve prediction of prognosis and survival outcomes in PCAS.PMID:37705234 | DOI:10.12659/MSM.942119
Source: Medical Science Monitor - September 14, 2023 Category: Research Authors: SooHyun Kim HeeWon Yang BangShill Rhee Hakyoon Song HyukHoon Kim Source Type: research

The Impact of Nasal Staphylococcus aureus Carriage on Surgical-Site Infections after Immediate Breast Reconstruction: Risk Factors and Biofilm Formation Potential
CONCLUSIONS There was no association between nasal carriage of strains of S. aureus and the incidence of SSI. However, further investigations on a larger group of patients and longer observation time are needed to investigate this potential risk factor in detail.PMID:37700508 | DOI:10.12659/MSM.940898
Source: Medical Science Monitor - September 13, 2023 Category: Research Authors: Maria Szymankiewicz Sylwia Jarzynka Anna Koryszewska-Bagi ńska Tomasz Nowikiewicz Source Type: research

Molecules, Vol. 28, Pages 6592: Determination of Calcium in Meat Products by Automatic Titration with 1,2-Diaminocyclohexane-N,N,N & rsquo;,N & rsquo;-tetraacetic Acid
Molecules, Vol. 28, Pages 6592: Determination of Calcium in Meat Products by Automatic Titration with 1,2-Diaminocyclohexane-N,N,N’,N’-tetraacetic Acid Molecules doi: 10.3390/molecules28186592 Authors: Alexander Shyichuk Maria Kowalska Iryna Shyychuk Jan Lamkiewicz Dorota Ziółkowska Mechanically separated meat (MSM) is a by-product of the poultry industry that requires routine quality assessment. Calcium content is an indirect indicator of bone debris in MSM but is difficult to determine by EDTA titration due to the poor solubility of calcium phosphate. Therefore, 1,2-diaminocyclohexan...
Source: Molecules - September 13, 2023 Category: Chemistry Authors: Alexander Shyichuk Maria Kowalska Iryna Shyychuk Jan Lamkiewicz Dorota Zi ółkowska Tags: Article Source Type: research

HCV knowledge and attitudes among HIV-negative MSM and MSM living with HIV in China: results from a cross-sectional online survey
Men who have sex with men (MSM) are at high risk of hepatitis C virus (HCV) infection, especially for those living with human immunodeficiency virus (HIV). Learning about knowledge of and attitudes towards HCV...
Source: BMC Infectious Diseases - September 13, 2023 Category: Infectious Diseases Authors: Wenqian Xu, Peizhen Zhao, Haiyi Li and Cheng Wang Tags: Research Source Type: research

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