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Infectious Disease: Hepatitis
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Total 32760 results found since Jan 2013.
Alzheimer's Disease as A Viral Infectious Disease: Revisiting the Infectious Hypothesis
Ageing Res Rev. 2023 Sep 11:102068. doi: 10.1016/j.arr.2023.102068. Online ahead of print.ABSTRACTAlzheimer's disease (AD) represents the most frequent type of dementia in elderly people. Two major forms of the disease exist: sporadic - the causes of which have not yet been fully understood - and familial - inherited within families from generation to generation, with a clear autosomal dominant transmission of mutations in Presenilin 1 (PSEN1), 2 (PSEN2) or Amyloid Precursors Protein (APP) genes. The main hallmark of AD consists of extracellular deposits of amyloid-beta (Aβ) peptide and intracellular deposits of the hyper...
Source: Ageing Research Reviews - September 13, 2023 Category: Genetics & Stem Cells Authors: Francesco Bruno Paolo Abondio Rossella Bruno Leognano Ceraudo Ersilia Pararazzo Luigi Citrigno Donata Luiselli Amalia C Bruni Giuseppe Passarino Rosanna Colao Raffaele Maletta Alberto Montesanto Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
Autoimmune hepatitis following mRNA COVID-19 vaccine
Therapie. 2023 Aug 29:S0040-5957(23)00109-9. doi: 10.1016/j.therap.2022.12.014. Online ahead of print.NO ABSTRACTPMID:37704459 | DOI:10.1016/j.therap.2022.12.014
Source: Therapie - September 13, 2023 Category: Psychiatry & Psychology Authors: Ahmed Zaiem Khouloud Ferchichi Ghozlane Lakhoua Widd Kaabi Imen Aouinti Sana Rebii Debbiche Sarrah Kastalli Lamia Kallel Ons Charfi Sihem El Aidli Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
Alzheimer's Disease as A Viral Infectious Disease: Revisiting the Infectious Hypothesis
Ageing Res Rev. 2023 Sep 11:102068. doi: 10.1016/j.arr.2023.102068. Online ahead of print.ABSTRACTAlzheimer's disease (AD) represents the most frequent type of dementia in elderly people. Two major forms of the disease exist: sporadic - the causes of which have not yet been fully understood - and familial - inherited within families from generation to generation, with a clear autosomal dominant transmission of mutations in Presenilin 1 (PSEN1), 2 (PSEN2) or Amyloid Precursors Protein (APP) genes. The main hallmark of AD consists of extracellular deposits of amyloid-beta (Aβ) peptide and intracellular deposits of the hyper...
Source: Herpes - September 13, 2023 Category: Infectious Diseases Authors: Francesco Bruno Paolo Abondio Rossella Bruno Leognano Ceraudo Ersilia Pararazzo Luigi Citrigno Donata Luiselli Amalia C Bruni Giuseppe Passarino Rosanna Colao Raffaele Maletta Alberto Montesanto Source Type: research
MicroRNA signature from extracellular vesicles of HCV/HIV co-infected individuals differs from HCV mono-infected
J Mol Med (Berl). 2023 Sep 14. doi: 10.1007/s00109-023-02367-8. Online ahead of print.ABSTRACTHepatitis C virus (HCV) coinfection with human immunodeficiency virus (HIV) has a detrimental impact on disease progression. Increasing evidence points to extracellular vesicles (EVs) as important players of the host-viral cross-talk. The microRNAs (miRNAs), as essential components of EVs cargo, are key regulators of normal cellular processes and also promote viral replication, viral pathogenesis, and disease progression. We aimed to characterize the plasma-derived EVs miRNA signature of chronic HCV infected and HIV coinfected pat...
Source: Molecular Medicine - September 13, 2023 Category: Molecular Biology Authors: Victoria Cairoli Daniel Valle-Millares Mar ía C Terrón-Orellano Daniel Luque Pablo Ryan Lourdes Dominguez Luz Mart ín-Carbonero Ignacio De Los Santos Elena De Matteo Beatriz Ameigeiras Ver ónica Briz Paola Casciato Mar ía Victoria Preciado Pamela Val Source Type: research
Autoimmune hepatitis following mRNA COVID-19 vaccine
Therapie. 2023 Aug 29:S0040-5957(23)00109-9. doi: 10.1016/j.therap.2022.12.014. Online ahead of print.NO ABSTRACTPMID:37704459 | DOI:10.1016/j.therap.2022.12.014
Source: Therapie - September 13, 2023 Category: Psychiatry & Psychology Authors: Ahmed Zaiem Khouloud Ferchichi Ghozlane Lakhoua Widd Kaabi Imen Aouinti Sana Rebii Debbiche Sarrah Kastalli Lamia Kallel Ons Charfi Sihem El Aidli Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research
Serum vitamin D deficiency is associated with increased risk of γδ T cell exhaustion in HBV-infected patients
In this study, we found that the frequency of circulating Vδ2+ T cell and serum levels of vitamin 25(OH)D3 were significantly decreased in patients with HBV. And serum 25(OH)D3 levels in HBV-infected patients were negatively correlated with HBV DNA load and PD-1 expression on γδ T cells. Interestingly, 1α,25(OH)2 D3 alleviated the exhaustion phenotype of Vδ2 T cells in HBV-infected patients and promoted IFN-β expression in human cytotoxic Vδ2 T cells in vitro. Collectively, these findings demonstrate that vitamin D plays a pivotal role in reversing γδ T-cell exhaustion and is highly promising target for ameliorati...
Source: Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Ke Li Eying Lu Qian Wang Ruirong Xu Wenhui Yuan Ruan Wu Ligong Lu Peng Li Source Type: research
Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research
