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Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Discontinuation of Nucleos(t)ide Analog treatment in HBeAg-Negative Non-Cirrhotic Chronic Hepatitis B Patients: Real-Life Data of 20 Years
CONCLUSION: In resource-limited areas where follow-up of HBsAg or other markers is not possible, nucleos(t)ide analog discontinuation can be considered in patients in the early stage, with low baseline hepatitis B virus DNA and ALT levels, after a long consolidation therapy.PMID:37681268 | DOI:10.5152/tjg.2023.22823
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Bilg ül Mete Sibel Y ıldız Kaya Abdurrahman Kaya Ahmet Furkan Kurt Osman Faruk Bayramlar R ıdvan Karaali İlker İnanç Balkan M ücahit Yemişen Re şat Özaras Ne şe Saltoğlu Fehmi Tabak Source Type: research
Risk of Hepatitis B Virus Reactivation in Patients with Resolved Infection on Therapy with Corticosteroids and Conventional Synthesis Immunosuppressants for Kidney Disease: A Single-Center Analysis of 258 Patients
CONCLUSIONS: Among patients with a previously resolved hepatitis B virus infection on therapy with corticosteroids and conventional synthesis immunosuppressants for kidney disease, hepatitis B virus reactivation was not common and severe, suggesting that universal prophylaxis may not be justified or cost-effective in this clinical setting.PMID:37681265 | DOI:10.5152/tjg.2023.22511
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: Pingyang Han Ziqiu Wang Zhaohui Wang Source Type: research
Towards an Improved Suppression of Maladaptive Inflammation
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical intervention.
Source: Fight Aging! - September 7, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Assessment of Disease Burden and Immunization Rates for Vaccine-Preventable Diseases in People Living with HIV: The Korea HIV/AIDS Cohort Study
CONCLUSION: The burden of vaccine-preventable diseases was quite high in HIV-infected patients. Nadir CD4 T-cell counts, peak HIV viral loads, and the number of ART regimen change are significant factors related to vaccination. Considering the low vaccination rates for VPDs, there was a discordance between experts' opinions and real clinical practice in the medical field.PMID:37674339 | DOI:10.3947/ic.2023.0045
Source: Herpes - September 7, 2023 Category: Infectious Diseases Authors: Hye Seong Yunsu Choi Kyoung Hwan Ahn Jun Yong Choi Shin-Woo Kim Sang Il Kim Mee-Kyung Kee Bo Youl Choi Boyoung Park Hak Jun Hyun Jin Gu Yoon Ji Yun Noh Hee Jin Cheong Woo Joo Kim Joon Young Song Source Type: research
Blueprint to hepatitis B elimination in China: A modelling analysis of clinical strategies
CONCLUSIONS: Eliminating HBV will require interventional strategies to improve diagnostic, linkage-to-care, and treatment coverages. Developing novel therapies will be crucial in further reducing HBV-related mortality and removing HBV as a public health threat.IMPACT AND IMPLICATIONS: This study explores the key developments and optimal intervention strategies needed to achieve WHO hepatitis B elimination targets by 2030 in China. It highlights that China can realise the HBV elimination targets in the incidence by 2025, and by upscaling diagnostic, linkage-to-care, and treatment coverages, up to 2 million lives could poten...
Source: Cancer Control - September 7, 2023 Category: Cancer & Oncology Authors: Rui Li Mingwang Shen Jason J Ong Fuqiang Cui Wenyi Hu Polin Chan Zhuoru Zou Shu Su Hangting Liu Lei Zhang Wai-Kay Seto William C W Wong Source Type: research
