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Infectious Disease: Hepatitis

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Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Autoimmune hepatitis following mRNA COVID-19 vaccine
Therapie. 2023 Aug 29:S0040-5957(23)00109-9. doi: 10.1016/j.therap.2022.12.014. Online ahead of print.NO ABSTRACTPMID:37704459 | DOI:10.1016/j.therap.2022.12.014
Source: Therapie - September 13, 2023 Category: Psychiatry & Psychology Authors: Ahmed Zaiem Khouloud Ferchichi Ghozlane Lakhoua Widd Kaabi Imen Aouinti Sana Rebii Debbiche Sarrah Kastalli Lamia Kallel Ons Charfi Sihem El Aidli Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Autoimmune hepatitis following mRNA COVID-19 vaccine
Therapie. 2023 Aug 29:S0040-5957(23)00109-9. doi: 10.1016/j.therap.2022.12.014. Online ahead of print.NO ABSTRACTPMID:37704459 | DOI:10.1016/j.therap.2022.12.014
Source: Therapie - September 13, 2023 Category: Psychiatry & Psychology Authors: Ahmed Zaiem Khouloud Ferchichi Ghozlane Lakhoua Widd Kaabi Imen Aouinti Sana Rebii Debbiche Sarrah Kastalli Lamia Kallel Ons Charfi Sihem El Aidli Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research

Hepatitis B virus infection in patients with Wilson disease: A large retrospective study
CONCLUSION: The total prevalence of current HBV infection in patients with WD was 2.1%. The diagnosis of WD in CHB patients is usually missed. HBV infection is an independent risk factor for severe liver disease in WD patients. The diagnosis of WD should be ruled out in some patients with CHB infection.PMID:37701133 | PMC:PMC10494763 | DOI:10.3748/wjg.v29.i32.4900
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Hua-Ying Zhou Xu Yang Kai-Zhong Luo Yong-Fang Jiang Wen-Long Wang Jun Liang Ming-Ming Li Hong-Yu Luo Source Type: research

Autoimmune hepatitis following mRNA COVID-19 vaccine
Therapie. 2023 Aug 29:S0040-5957(23)00109-9. doi: 10.1016/j.therap.2022.12.014. Online ahead of print.NO ABSTRACTPMID:37704459 | DOI:10.1016/j.therap.2022.12.014
Source: Therapie - September 13, 2023 Category: Psychiatry & Psychology Authors: Ahmed Zaiem Khouloud Ferchichi Ghozlane Lakhoua Widd Kaabi Imen Aouinti Sana Rebii Debbiche Sarrah Kastalli Lamia Kallel Ons Charfi Sihem El Aidli Source Type: research

Maternal A90V mutation in the PreS1 gene of sub-genotype C2 hepatitis B virus is associated with intrauterine transmission
Rev Inst Med Trop Sao Paulo. 2023 Sep 8;65:e46. doi: 10.1590/S1678-9946202365046. eCollection 2023.ABSTRACTPreS/S gene mutations could impact virus secretion, infection and immune evasion. However, the relationship between PreS/S mutations and intrauterine transmission has not yet been clarified. Thus, we aimed to explore the associations between PreS/S gene mutations of HBV isolated from mothers and intrauterine transmission. We analyzed the mutations of PreS/S regions of the HBV genome in mothers with HBV DNA levels ≥ 106 IU/mL whose neonates experienced HBV intrauterine transmission (transmission group, GT) and those ...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - September 13, 2023 Category: Tropical Medicine Authors: Linzhu Yi Jiaxin Wu Zhiqing Yang Yandi Li Jia Lian Tian Yao Shuying Feng Bo Wang Yongliang Feng Suping Wang Source Type: research

Association of giant cell hepatitis and autoimmune hemolytic anemia in infancy
Orv Hetil. 2023 Sep 10;164(36):1432-1436. doi: 10.1556/650.2023.32848. Print 2023 Sep 10.ABSTRACTGiant cell hepatitis associated with autoimmune hemolytic anemia (GCH-AIHA) is a rare disorder with unfavorable prognosis, affecting infants and young children. The mortality rate is high, complications of acute liver failure, sepsis, or liver transplantation can be responsible for fatal outcomes. An 18-month-old child who was diagnosed previously with autoimmune hemolytic anemia, developed acute hepatitis and acute liver failure concomitant to the relapse of the disease. GCH-AIHA is characterized by Coombs positive hemolytic a...
Source: Orvosi Hetilap - September 11, 2023 Category: General Medicine Authors: Katalin Csernus Alexandra T észás G ábor Ottóffy Antal Dezs őfi-Gottl Andr ás Tárnok Source Type: research

The hepatitis B virus pre-core protein p22 suppresses TNF α-induced apoptosis by regulating the NF-κB pathway
CONCLUSIONS: Collectively, HBV-p22, whereby the mechanism contributing to anti-apoptotic effect was regulation of the NF-κB pathway via enhancing the phosphorylation of IKKα.PMID:37692946 | PMC:PMC10492049
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Zhihong Diao Huan Luo Ying Li Zhenli Ma Fangmei Tang Buqing Cao Yuqing Feng Zhongsong Mo Hongjun Gao Source Type: research