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Infectious Disease: HIV AIDS

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Total 15008 results found since Jan 2013.

Nanovesicular-Mediated Intranasal Drug Therapy for Neurodegenerative Disease
In conclusion, the review covers in-depth conclusions on numerous aspects of formulation of drug-loaded vesicular system delivery across BBB, current marketed nasal devices, significant jeopardies, potential therapeutic aids, and current advancements followed by future perspectives.PMID:37658972 | DOI:10.1208/s12249-023-02625-5
Source: AAPS PharmSciTech - September 2, 2023 Category: Drugs & Pharmacology Authors: Shalu Singh Rahul Shukla Source Type: research

A qualitative study assessing the barriers and facilitators to physical activity in adults with hearing loss
CONCLUSIONS: Middle-aged and older adults with hearing loss experience hearing-specific barriers to physical activity, which has a deleterious impact on their overall health and well-being. Interventions and public health programmes need to be tailored to account for these additional barriers. Further research is necessary to test potential behaviour change techniques.PMID:37658583 | DOI:10.1111/bjhp.12689
Source: British Journal of Health Psychology - September 2, 2023 Category: Psychiatry & Psychology Authors: Maria V Goodwin Eef Hogervorst David W Maidment Source Type: research

Nanovesicular-Mediated Intranasal Drug Therapy for Neurodegenerative Disease
In conclusion, the review covers in-depth conclusions on numerous aspects of formulation of drug-loaded vesicular system delivery across BBB, current marketed nasal devices, significant jeopardies, potential therapeutic aids, and current advancements followed by future perspectives.PMID:37658972 | DOI:10.1208/s12249-023-02625-5
Source: AAPS PharmSciTech - September 2, 2023 Category: Drugs & Pharmacology Authors: Shalu Singh Rahul Shukla Source Type: research

A qualitative study assessing the barriers and facilitators to physical activity in adults with hearing loss
CONCLUSIONS: Middle-aged and older adults with hearing loss experience hearing-specific barriers to physical activity, which has a deleterious impact on their overall health and well-being. Interventions and public health programmes need to be tailored to account for these additional barriers. Further research is necessary to test potential behaviour change techniques.PMID:37658583 | DOI:10.1111/bjhp.12689
Source: British Journal of Health Psychology - September 2, 2023 Category: Psychiatry & Psychology Authors: Maria V Goodwin Eef Hogervorst David W Maidment Source Type: research

Inhibition of myeloid-derived suppressor cell (MDSC) activity by redox-modulating agents restores T and B cell proliferative responses in murine AIDS
This study preliminarily explored the role of two redox-modulating compounds in inhibiting the M-MDSC suppressive activity in LP-BM5 infection. The tested molecules were: I-152 consisting in a conjugate of N-acetyl-cysteine (NAC) and S-acetyl-cysteamine (SMEA) and C4-GSH that is the n-butanoyl glutathione (GSH) derivative. The results show that both molecules, tested in a concentration range between 3 and 20 mM, blocked the M-MDSC suppression of activated B and T cells ex vivo and restored their proliferative capacity in vivo. Ex vivo I-152 blockade of M-MDSC suppressiveness was more significant for T cell (about 70%) whil...
Source: International Immunopharmacology - September 2, 2023 Category: Allergy & Immunology Authors: Alessandra Fraternale Kathy A Green Giuditta F Schiavano Michela Bruschi Michele Retini Mauro Magnani William R Green Source Type: research

A qualitative study assessing the barriers and facilitators to physical activity in adults with hearing loss
CONCLUSIONS: Middle-aged and older adults with hearing loss experience hearing-specific barriers to physical activity, which has a deleterious impact on their overall health and well-being. Interventions and public health programmes need to be tailored to account for these additional barriers. Further research is necessary to test potential behaviour change techniques.PMID:37658583 | DOI:10.1111/bjhp.12689
Source: British Journal of Health Psychology - September 2, 2023 Category: Psychiatry & Psychology Authors: Maria V Goodwin Eef Hogervorst David W Maidment Source Type: research

Nanovesicular-Mediated Intranasal Drug Therapy for Neurodegenerative Disease
In conclusion, the review covers in-depth conclusions on numerous aspects of formulation of drug-loaded vesicular system delivery across BBB, current marketed nasal devices, significant jeopardies, potential therapeutic aids, and current advancements followed by future perspectives.PMID:37658972 | DOI:10.1208/s12249-023-02625-5
Source: AAPS PharmSciTech - September 2, 2023 Category: Drugs & Pharmacology Authors: Shalu Singh Rahul Shukla Source Type: research

A qualitative study assessing the barriers and facilitators to physical activity in adults with hearing loss
CONCLUSIONS: Middle-aged and older adults with hearing loss experience hearing-specific barriers to physical activity, which has a deleterious impact on their overall health and well-being. Interventions and public health programmes need to be tailored to account for these additional barriers. Further research is necessary to test potential behaviour change techniques.PMID:37658583 | DOI:10.1111/bjhp.12689
Source: British Journal of Health Psychology - September 2, 2023 Category: Psychiatry & Psychology Authors: Maria V Goodwin Eef Hogervorst David W Maidment Source Type: research