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A cross-comparative analysis of in vivo versus ex vivo MRI indices in a mouse model of concussion
CONCLUSION: Our findings call for caution in extrapolating translational capabilities obtained ex vivo to physiological measurements in vivo. The divergent findings may reflect fixation artefacts and the contribution of the glymphatic system changes.PMID:37673379 | DOI:10.1016/j.brainres.2023.148562
Source: Brain Research - September 6, 2023 Category: Neurology Authors: Xuan Vinh To Nyoman D Kurniawan Paul Cummingc Fatima A Nasrallah Source Type: research

Imaging of dysthyroid optic neuropathy
This article summarises the definition, prevalence, and utility of these radiological findings in the diagnosis of DON.PMID:37671438 | DOI:10.1177/11206721231199367
Source: European Journal of Ophthalmology - September 6, 2023 Category: Opthalmology Authors: Khizar Rana Devanshu Garg Sandy Patel Dinesh Selva Source Type: research

Continuous time-resolved estimated synthetic 4D-CTs for dose reconstruction of lung tumor treatments at a 0.35 T MR-linac
Phys Med Biol. 2023 Sep 5. doi: 10.1088/1361-6560/acf6f0. Online ahead of print.ABSTRACTTo experimentally validate a method to create continuous time-resolved estimated synthetic 4D-computed tomography datasets (tresCTs) based on orthogonal cine MRI data for lung cancer treatments at a magnetic resonance imaging (MRI)-guided linear accelerator (MR-linac).
Approach. A breathing porcine lung phantom was scanned at a CT scanner and 0.35 T MR-linac. Orthogonal cine MRI series (sagittal/coronal orientation) at 7.3 Hz, intersecting tumor-mimicking gelatin nodules, were deformably registered to mid-exhale 3D-CT and 3D-MRI...
Source: Physics in Medicine and Biology - September 5, 2023 Category: Physics Authors: Moritz Rabe Chiara Paganelli Henning Peter Schmitz Giorgia Meschini Marco Riboldi Jan Hofmaier Lukas Nierer-Kohlhase Julien Dinkel Michael Reiner Katia Parodi Claus Belka Guillaume Landry Christopher Kurz Florian Kamp Source Type: research

Functional assessment in endometrial and cervical cancer: diffusion and perfusion, two captivating tools for radiologists
Eur Rev Med Pharmacol Sci. 2023 Aug;27(16):7793-7810. doi: 10.26355/eurrev_202308_33435.ABSTRACTUterine cervical and endometrial cancers are two major gynecological malignancies, affecting women's health worldwide. Magnetic resonance imaging (MRI) is appropriate for evaluating malignant disease, thanks to the excellent soft tissue contrast and multiplanar imaging ability. Recently, functional MR techniques, namely diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE), have proved to be a precious support not only in cancer diagnosis but also in disease staging, in the therapy planning, in monitoring ...
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: F De Muzio R Fusco I Simonetti F Grassi R Grassi M C Brunese L Ravo N Maggialetti R D'Aniello F Greco M Gabelloni V Granata Source Type: research

Continuous time-resolved estimated synthetic 4D-CTs for dose reconstruction of lung tumor treatments at a 0.35 T MR-linac
Phys Med Biol. 2023 Sep 5. doi: 10.1088/1361-6560/acf6f0. Online ahead of print.ABSTRACTTo experimentally validate a method to create continuous time-resolved estimated synthetic 4D-computed tomography datasets (tresCTs) based on orthogonal cine MRI data for lung cancer treatments at a magnetic resonance imaging (MRI)-guided linear accelerator (MR-linac).
Approach. A breathing porcine lung phantom was scanned at a CT scanner and 0.35 T MR-linac. Orthogonal cine MRI series (sagittal/coronal orientation) at 7.3 Hz, intersecting tumor-mimicking gelatin nodules, were deformably registered to mid-exhale 3D-CT and 3D-MRI...
Source: Physics in Medicine and Biology - September 5, 2023 Category: Physics Authors: Moritz Rabe Chiara Paganelli Henning Peter Schmitz Giorgia Meschini Marco Riboldi Jan Hofmaier Lukas Nierer-Kohlhase Julien Dinkel Michael Reiner Katia Parodi Claus Belka Guillaume Landry Christopher Kurz Florian Kamp Source Type: research

Functional assessment in endometrial and cervical cancer: diffusion and perfusion, two captivating tools for radiologists
Eur Rev Med Pharmacol Sci. 2023 Aug;27(16):7793-7810. doi: 10.26355/eurrev_202308_33435.ABSTRACTUterine cervical and endometrial cancers are two major gynecological malignancies, affecting women's health worldwide. Magnetic resonance imaging (MRI) is appropriate for evaluating malignant disease, thanks to the excellent soft tissue contrast and multiplanar imaging ability. Recently, functional MR techniques, namely diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE), have proved to be a precious support not only in cancer diagnosis but also in disease staging, in the therapy planning, in monitoring ...
Source: Pharmacological Reviews - September 5, 2023 Category: Drugs & Pharmacology Authors: F De Muzio R Fusco I Simonetti F Grassi R Grassi M C Brunese L Ravo N Maggialetti R D'Aniello F Greco M Gabelloni V Granata Source Type: research

GAN-based metal artifacts region inpainting in brain MRI imaging with reflective registration
CONCLUSIONS: By leveraging the quasi-symmetry of brain MRI images, MARINet can directly and effectively inpaint the metal artifacts in MRI images in the image domain, restoring the tooth contour and detail, thereby enhancing the image quality.PMID:37665773 | DOI:10.1002/mp.16724
Source: Health Physics - September 4, 2023 Category: Physics Authors: Kai Xie Liugang Gao Heng Zhang Sai Zhang Qianyi Xi Fan Zhang Jiawei Sun Tao Lin Jianfeng Sui Xinye Ni Source Type: research

A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology : The Turkish Society of Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research

Diagnostic value of MRI radiomics in differentiating high ‑grade glioma from low‑grade glioma: A meta‑analysis
Oncol Lett. 2023 Aug 23;26(4):436. doi: 10.3892/ol.2023.14023. eCollection 2023 Oct.ABSTRACTNo clear conclusions have yet been reached regarding the accuracy of magnetic resonance imaging (MRI) radiomics in distinguishing high-grade glioma (HGG) from low-grade glioma (LGG). In the present study, a meta-analysis was conducted to determine the diagnostic value of MRI radiomics in differentiating between HGG and LGG, in order to guide their clinical diagnosis. PubMed, Embase and the Cochrane Library databases were searched up to November 2022. The search included studies in which true positive, false positive, true negative a...
Source: Oncology Letters - September 4, 2023 Category: Cancer & Oncology Authors: Jiefang Wang Zhichao Chen Jieyun Chen Source Type: research

Anti-SOX-1 Antibody-Positive Paraneoplastic Limbic Encephalitis Diagnosed During Small Cell Lung Cancer Treatment
We present a case of anti-Sry-like high mobility group box 1 (SOX-1) antibody-positive PNS diagnosed during the treatment of small-cell lung cancer (SCLC). A 65-year-old woman with a history of smoking and SCLC (T3N1M0) was hospitalized to receive chemo-radiation therapy. On day 14, the course was complicated by left mastitis associated with febrile neutropenia. Drainage was performed for the left mastitis, and cefepime was initiated. The fever subsided within a few days, but the patient became agitated accompanied by logorrhea. With the exception of mental status, her neurological examination was unremarkable. Due to mild...
Source: Herpes - September 4, 2023 Category: Infectious Diseases Authors: Toru Yoshino Ryuta Yamamoto Yoji Hoshina Tomohiko Ishimine Source Type: research

Intratumoral heterogeneity after targeted therapy in murine cancer models with differing degrees of malignancy
In conclusion, mp MRI enables to assess dedicated therapy-related intratumoral changes and may serve as a biomarker for treatment response assessment.PMID:37666208 | DOI:10.1016/j.tranon.2023.101773
Source: Translational Oncology - September 4, 2023 Category: Cancer & Oncology Authors: M Gerwing E Hoffmann C Geyer A Helfen B Maus R Schinner L Wachsmuth W Heindel M Eisenblaetter C Faber M Wildgruber Source Type: research

Diagnostic value of MRI radiomics in differentiating high ‑grade glioma from low‑grade glioma: A meta‑analysis
Oncol Lett. 2023 Aug 23;26(4):436. doi: 10.3892/ol.2023.14023. eCollection 2023 Oct.ABSTRACTNo clear conclusions have yet been reached regarding the accuracy of magnetic resonance imaging (MRI) radiomics in distinguishing high-grade glioma (HGG) from low-grade glioma (LGG). In the present study, a meta-analysis was conducted to determine the diagnostic value of MRI radiomics in differentiating between HGG and LGG, in order to guide their clinical diagnosis. PubMed, Embase and the Cochrane Library databases were searched up to November 2022. The search included studies in which true positive, false positive, true negative a...
Source: Oncology Letters - September 4, 2023 Category: Cancer & Oncology Authors: Jiefang Wang Zhichao Chen Jieyun Chen Source Type: research

A model incorporating clinicopathologic and liver imaging reporting and data system-based magnetic resonance imaging features to identify hepatocellular carcinoma in LR-M observations
CONCLUSION: The combined model incorporating clinicopathologic and MRI features demonstrated a satisfactory prediction result for LR-M HCC.PMID:37665140 | DOI:10.4274/dir.2023.232215
Source: Diagnostic and Interventional Radiology - September 4, 2023 Category: Radiology Authors: Xin-Xing Hu Dong Bai Zhen-Lei Wang Yi Zhang Jue Zhao Mei-Ling Li Jia Yang Lei Zhang Source Type: research

The value of multimodal functional magnetic resonance imaging in differentiating p53abn from p53wt endometrial carcinoma
CONCLUSION: APTw, mDIXON-Quant and DWI techniques can be usedfor quantitative identification of p53abn and p53wt EC. The multimodal MRI provides a new way for preoperative quantitative evaluation of EC molecular typing, which has certain clinical application value.PMID:37661630 | DOI:10.1177/02841851231198911
Source: Acta Radiologica - September 4, 2023 Category: Radiology Authors: Tian Shifeng Wang Yue Zhu Wen Chen Lihua Wang Nan Lin Liangjie Liu Ailian Source Type: research

Anti-SOX-1 Antibody-Positive Paraneoplastic Limbic Encephalitis Diagnosed During Small Cell Lung Cancer Treatment
We present a case of anti-Sry-like high mobility group box 1 (SOX-1) antibody-positive PNS diagnosed during the treatment of small-cell lung cancer (SCLC). A 65-year-old woman with a history of smoking and SCLC (T3N1M0) was hospitalized to receive chemo-radiation therapy. On day 14, the course was complicated by left mastitis associated with febrile neutropenia. Drainage was performed for the left mastitis, and cefepime was initiated. The fever subsided within a few days, but the patient became agitated accompanied by logorrhea. With the exception of mental status, her neurological examination was unremarkable. Due to mild...
Source: Herpes - September 4, 2023 Category: Infectious Diseases Authors: Toru Yoshino Ryuta Yamamoto Yoji Hoshina Tomohiko Ishimine Source Type: research