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Individualizing Breast Cancer Risk Assessment in Clinical Practice
Surg Oncol Clin N Am. 2023 Oct;32(4):647-661. doi: 10.1016/j.soc.2023.05.013. Epub 2023 Jul 6.ABSTRACTMultiple tools exist to assess a patient's breast cancer risk. The choice of risk model depends on the patient's risk factors and how the calculation will impact care. High-risk patients-those with a lifetime breast cancer risk of ≥20%-are, for instance, eligible for supplemental screening with breast magnetic resonance imaging. Those with an elevated short-term breast cancer risk (frequently defined as a 5-year risk ≥1.66%) should be offered endocrine prophylaxis. High-risk patients should also receive guidance on mod...
Source: Clinical Breast Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Amy E Cyr Kaitlyn Kennard Source Type: research
Tumoral and peritumoral vascularization of brain tumours: a study comparing an intraoperative ultrasensitive Doppler and a preoperative first-pass perfusion MRI
CONCLUSION: There was a good correlation between a tumor FMBV obtained by a USD intraoperatively and rCCBV on a preoperative MRI validating the reliability of USD for intraoperative analyses of tumor microvascularization in gliomas.PMID:37714376 | DOI:10.1016/j.neuchi.2023.101493
Source: Neuro-Chirurgie - September 15, 2023 Category: Neurosurgery Authors: Camille Courtin Guillaume Lacoin Jean-Pierre Remenieras C écilia Denis Rousselot Paul-Armand Dujardin Ilyess Zemmoura Jean-Philippe Cottier Source Type: research
ANGPTL3 Deficiency and Risk of Hepatic Steatosis
CONCLUSIONS: ANGPTL3 deficiency related to LoF mutations in ANGPTL3, as well as genetically determined reduction of plasma ANGPTL3 levels, is not associated with hepatic steatosis. Therapeutic approaches to inhibit ANGPTL3 production in hepatocytes are not necessarily expected to result in the increased risk for hepatic steatosis that was observed with vupanorsen.PMID:37712257 | DOI:10.1161/CIRCULATIONAHA.123.065866
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Laura D'Erasmo Michele Di Martino Thomas Neufeld Tyler J Fraum Chul Joo Kang Kendall H Burks Alessia Di Costanzo Ilenia Minicocci Simone Bini Marianna Maranghi Giovanni Pigna Giancarlo Labbadia Jie Zheng Davide Fierro Anna Montali Fabrizio Ceci Carlo Cata Source Type: research
Physical model-based cascaded generative adversarial networks for accelerating quantitative multi-parametric magnetic resonance imaging
CONCLUSION: Compared with other existing methods, the physical model-based cascaded generative adversarial networks can reconstruct more image details and features, thus improving the quality and accuracy of the reconstructed images.PMID:37712278 | PMC:PMC10505569 | DOI:10.12122/j.issn.1673-4254.2023.08.18
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Liu Z Chu Y Zhang Source Type: research
Individualizing Breast Cancer Risk Assessment in Clinical Practice
Surg Oncol Clin N Am. 2023 Oct;32(4):647-661. doi: 10.1016/j.soc.2023.05.013. Epub 2023 Jul 6.ABSTRACTMultiple tools exist to assess a patient's breast cancer risk. The choice of risk model depends on the patient's risk factors and how the calculation will impact care. High-risk patients-those with a lifetime breast cancer risk of ≥20%-are, for instance, eligible for supplemental screening with breast magnetic resonance imaging. Those with an elevated short-term breast cancer risk (frequently defined as a 5-year risk ≥1.66%) should be offered endocrine prophylaxis. High-risk patients should also receive guidance on mod...
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Amy E Cyr Kaitlyn Kennard Source Type: research
Effect of dominant vertebral artery angle on basilar artery curvature and plaque
CONCLUSIONS: The dominant VA angle was independently associated with BA plaque, and a dominant VA angle greater than 80° may be a marker for a high risk of posterior circulation atherosclerosis.PMID:37711832 | PMC:PMC10498226 | DOI:10.21037/qims-23-74
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Yangchen Li Runcai Guo Xuebing Zhang Yang Yang Yuchun Yan Xinyu Yuan Ce Wang Sheng Xie Source Type: research
Safety, accuracy, and prediction of prognosis in patients with end-stage chronic kidney disease undergoing dobutamine stress cardiac magnetic resonance imaging
DISCUSSION: Dobutamine stress CMR is a safe and accurate diagnostic imaging technique in patients at advanced stages of chronic kidney disease. A reduced ejection fraction and the inability to reach the target heart rate are independent predictors of a poor outcome.PMID:37711564 | PMC:PMC10498284 | DOI:10.3389/fcvm.2023.1228691
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Lukas D Weberling Sebastian Seitz Janek Salatzki Andreas Ochs Ail ís C Haney Deborah Siry Jannick Heins Henning Steen Norbert Frey Florian Andr é Source Type: research
Value of Echocardiography and Cardiac Magnetic resonance in assessing left ventricular function in breast and gastric cancer patients after Anthracycline Chemotherapy
CONCLUSION: Breast and gastric cancer patients exhibited elevated levels of hs-cTnT after 6 cycles of chemotherapy, indicating potential cardiotoxicity. Additionally, cardiac MRI and 2-dimensional ECHO showed good agreement in assessing left ventricular function, with ECHO tending to underestimate volume measurements compared to MRI.PMID:37715125 | PMC:PMC10504696 | DOI:10.1186/s12872-023-03495-2
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Chao-Long Jin Xue-Gong Shi Ting-Ting Wang Hong-Wen Li Ding-Xin Zhang Zhe Sheng Jie Xiao Yong-Qiang Yu Source Type: research
Physical model-based cascaded generative adversarial networks for accelerating quantitative multi-parametric magnetic resonance imaging
CONCLUSION: Compared with other existing methods, the physical model-based cascaded generative adversarial networks can reconstruct more image details and features, thus improving the quality and accuracy of the reconstructed images.PMID:37712278 | PMC:PMC10505569 | DOI:10.12122/j.issn.1673-4254.2023.08.18
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Liu Z Chu Y Zhang Source Type: research
A Dual-Aware deep learning framework for identification of glioma isocitrate dehydrogenase genotype using magnetic resonance amide proton transfer modalities
CONCLUSION: The proposed deep learning algorithm model constructed based on the image characteristics of the APT modality is effective for glioma IDH genotyping and identification task and may potentially replace the commonly used T1CE modality to avoid contrast agent injection and achieve non- invasive IDH genotyping.PMID:37712275 | PMC:PMC10505564 | DOI:10.12122/j.issn.1673-4254.2023.08.15
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chu Y Qu T Zhong S Liang Z Wen Y Zhang Source Type: research
Physical model-based cascaded generative adversarial networks for accelerating quantitative multi-parametric magnetic resonance imaging
CONCLUSION: Compared with other existing methods, the physical model-based cascaded generative adversarial networks can reconstruct more image details and features, thus improving the quality and accuracy of the reconstructed images.PMID:37712278 | DOI:10.12122/j.issn.1673-4254.2023.08.18
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Liu Z Chu Y Zhang Source Type: research
A Dual-Aware deep learning framework for identification of glioma isocitrate dehydrogenase genotype using magnetic resonance amide proton transfer modalities
CONCLUSION: The proposed deep learning algorithm model constructed based on the image characteristics of the APT modality is effective for glioma IDH genotyping and identification task and may potentially replace the commonly used T1CE modality to avoid contrast agent injection and achieve non- invasive IDH genotyping.PMID:37712275 | DOI:10.12122/j.issn.1673-4254.2023.08.15
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chu Y Qu T Zhong S Liang Z Wen Y Zhang Source Type: research
Tumoral and peritumoral vascularization of brain tumours: a study comparing an intraoperative ultrasensitive Doppler and a preoperative first-pass perfusion MRI
CONCLUSION: There was a good correlation between a tumor FMBV obtained by a USD intraoperatively and rCCBV on a preoperative MRI validating the reliability of USD for intraoperative analyses of tumor microvascularization in gliomas.PMID:37714376 | DOI:10.1016/j.neuchi.2023.101493
Source: Neuro-Chirurgie - September 15, 2023 Category: Neurosurgery Authors: Camille Courtin Guillaume Lacoin Jean-Pierre Remenieras C écilia Denis Rousselot Paul-Armand Dujardin Ilyess Zemmoura Jean-Philippe Cottier Source Type: research
Individualizing Breast Cancer Risk Assessment in Clinical Practice
Surg Oncol Clin N Am. 2023 Oct;32(4):647-661. doi: 10.1016/j.soc.2023.05.013. Epub 2023 Jul 6.ABSTRACTMultiple tools exist to assess a patient's breast cancer risk. The choice of risk model depends on the patient's risk factors and how the calculation will impact care. High-risk patients-those with a lifetime breast cancer risk of ≥20%-are, for instance, eligible for supplemental screening with breast magnetic resonance imaging. Those with an elevated short-term breast cancer risk (frequently defined as a 5-year risk ≥1.66%) should be offered endocrine prophylaxis. High-risk patients should also receive guidance on mod...
Source: Clinical Genitourinary Cancer - September 15, 2023 Category: Cancer & Oncology Authors: Amy E Cyr Kaitlyn Kennard Source Type: research
ANGPTL3 Deficiency and Risk of Hepatic Steatosis
CONCLUSIONS: ANGPTL3 deficiency related to LoF mutations in ANGPTL3, as well as genetically determined reduction of plasma ANGPTL3 levels, is not associated with hepatic steatosis. Therapeutic approaches to inhibit ANGPTL3 production in hepatocytes are not necessarily expected to result in the increased risk for hepatic steatosis that was observed with vupanorsen.PMID:37712257 | DOI:10.1161/CIRCULATIONAHA.123.065866
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Laura D'Erasmo Michele Di Martino Thomas Neufeld Tyler J Fraum Chul Joo Kang Kendall H Burks Alessia Di Costanzo Ilenia Minicocci Simone Bini Marianna Maranghi Giovanni Pigna Giancarlo Labbadia Jie Zheng Davide Fierro Anna Montali Fabrizio Ceci Carlo Cata Source Type: research
