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Total 38806 results found since Jan 2013.
Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease
CONCLUSION: Our findings reveal that the topological features of brain networks and cortical thickness are altered in PD patients with cognitive deficits. The above change, accompanied by the serum GDNF, may have merit as a diagnosis marker for PD and, arguably, cognition status.PMID:37718594 | DOI:10.1111/cns.14461
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Chuanxi Tang Ruiao Sun Ke Xue Mengying Wang Sijie Liang Piniel Alphayo Kambey Mingyu Shi Changyu Wu Gang Chen Dianshuai Gao Source Type: research
Bone marrow edema at ligament insertion is an accurate MRI sign of deltoid ligament injury
CONCLUSION: BMELI can reliably indicate concomitant injury to the DL in CAI patients. Using BMELI as a sign of chronic DL injury when ALMC is unclear may reduce the risk of a false negative diagnosis.PMID:37722764 | DOI:10.1177/02841851231197508
Source: Acta Radiologica - September 18, 2023 Category: Radiology Authors: Jiahui Tong Hong Li Hongyun Li Yinghui Hua Source Type: research
mpMRI-targeted biopsy of the prostate in men ≥ 75 years. 7-year report from a high-volume referral center
CONCLUSION: After evaluation of a large patient cohort, we show that age≥75 years represents a significant risk factor for the detection of clinically significant prostate cancer. Further studies on mid- and long term outcome are necessary to draw conclusions for clinical decision making in this patient cohort.PMID:37718788 | DOI:10.3233/CH-238101
Source: Clinical Hemorheology and Microcirculation - September 18, 2023 Category: Hematology Authors: Michael Chaloupka Nikolaos Pyrgidis Benedikt Ebner Paulo Pfitzinger Yannic Volz Elena Berg Benazir Abrarova Michael Atzler Troya Ivanova Paulo Pfitzinger Christian G Stief Maria Apfelbeck Dirk-Andr é Clevert Source Type: research
Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research
Baseline prostate health index risk category and risk category changes during active surveillance predict grade reclassification
CONCLUSIONS: Baseline PHI risk category and PHI changes over time were both independent predictors of GR after confirmatory biopsy, but the added benefit over PSAD seemed modest. However, baseline PHI and PHI risk category changes provided clinically useful risk stratification for time to GR, so further evaluation of PHI's ability to help reduce the frequency of mpMRI and/or surveillance biopsies with more PHI data points over time may be warranted.PMID:37722985 | DOI:10.1016/j.urolonc.2023.08.011
Source: Urologic Oncology - September 18, 2023 Category: Urology & Nephrology Authors: Claire M de la Calle Yuezhou Jing Mufaddal M Mamawala Patricia Landis Katarzyna J Macura Bruce J Trock Jonathan I Epstein Lori J Sokoll Christian P Pavlovich Source Type: research
Probability of Cavitation in a Custom Iron-Based Coupling Medium for Transcranial Magnetic Resonance-Guided Focused Ultrasound Procedures
A coupling bath of circulating, chilled, degassed water is essential to safe and precise acoustic transmittance during transcranial magnetic resonance-guided focused ultrasound (tMRgFUS) procedures, but the circulating water impairs the critical real-time magnetic resonance imaging (MRI). An iron-based coupling medium (IBCM) using iron oxide nanoparticles previously developed by our group increased the relaxivity of the coupling bath such that it appears to be invisible on MRI compared with degassed water.
Source: Ultrasound in Medicine and Biology - September 18, 2023 Category: Radiology Authors: Connor Edsall, Austin Fergusson, Richey M. Davis, Craig H. Meyer, Steven P. Allen, Eli Vlaisavljevich Tags: Original Contribution Source Type: research
White Noise-Is Anxiety in Late-Life Associated With White Matter Hyperintensity Burden?
CONCLUSION: Longitudinal studies are needed in order to clarify the complex interactions between anxiety phenotypes, WMH, and EF.PMID:37718134 | DOI:10.1016/j.jagp.2023.08.014
Source: Am J Geriatr Psychia... - September 17, 2023 Category: Geriatrics Authors: Andrew R Gerlach Helmet T Karim Soyoung Lee Antonija Kolobaric Dana L Tudorascu Meryl A Butters Carmen Andreescu Source Type: research
Multimodal imaging of microstructural cerebral alterations and loss of synaptic density in Alzheimer's disease
Neurobiol Aging. 2023 Aug 9;132:24-35. doi: 10.1016/j.neurobiolaging.2023.08.001. Online ahead of print.ABSTRACTMultiple neuropathological events are involved in Alzheimer's disease (AD). The current study investigated the concurrence of neurodegeneration, increased iron content, atrophy, and demyelination in AD. Quantitative multiparameter magnetic resonance imaging (MRI) maps providing neuroimaging biomarkers for myelination and iron content along with synaptic density measurements using [18F] UCB-H PET were acquired in 24 AD and 19 Healthy controls (19 males). The whole brain voxel-wise group comparison revealed demyeli...
Source: Neurobiology of Aging - September 17, 2023 Category: Geriatrics Authors: Soodeh Moallemian Eric Salmon Mohamed Ali Bahri Nikita Beliy Emma Delhaye Evelyne Balteau Christian Degueldre Christophe Phillips Christine Bastin Source Type: research
White Noise-Is Anxiety in Late-Life Associated With White Matter Hyperintensity Burden?
CONCLUSION: Longitudinal studies are needed in order to clarify the complex interactions between anxiety phenotypes, WMH, and EF.PMID:37718134 | DOI:10.1016/j.jagp.2023.08.014
Source: Am J Geriatr Psychia... - September 17, 2023 Category: Geriatrics Authors: Andrew R Gerlach Helmet T Karim Soyoung Lee Antonija Kolobaric Dana L Tudorascu Meryl A Butters Carmen Andreescu Source Type: research
Multimodal imaging of microstructural cerebral alterations and loss of synaptic density in Alzheimer's disease
Neurobiol Aging. 2023 Aug 9;132:24-35. doi: 10.1016/j.neurobiolaging.2023.08.001. Online ahead of print.ABSTRACTMultiple neuropathological events are involved in Alzheimer's disease (AD). The current study investigated the concurrence of neurodegeneration, increased iron content, atrophy, and demyelination in AD. Quantitative multiparameter magnetic resonance imaging (MRI) maps providing neuroimaging biomarkers for myelination and iron content along with synaptic density measurements using [18F] UCB-H PET were acquired in 24 AD and 19 Healthy controls (19 males). The whole brain voxel-wise group comparison revealed demyeli...
Source: Neurobiology of Aging - September 17, 2023 Category: Geriatrics Authors: Soodeh Moallemian Eric Salmon Mohamed Ali Bahri Nikita Beliy Emma Delhaye Evelyne Balteau Christian Degueldre Christophe Phillips Christine Bastin Source Type: research
White Noise-Is Anxiety in Late-Life Associated With White Matter Hyperintensity Burden?
CONCLUSION: Longitudinal studies are needed in order to clarify the complex interactions between anxiety phenotypes, WMH, and EF.PMID:37718134 | DOI:10.1016/j.jagp.2023.08.014
Source: Am J Geriatr Psychia... - September 17, 2023 Category: Geriatrics Authors: Andrew R Gerlach Helmet T Karim Soyoung Lee Antonija Kolobaric Dana L Tudorascu Meryl A Butters Carmen Andreescu Source Type: research
Multimodal imaging of microstructural cerebral alterations and loss of synaptic density in Alzheimer's disease
Neurobiol Aging. 2023 Aug 9;132:24-35. doi: 10.1016/j.neurobiolaging.2023.08.001. Online ahead of print.ABSTRACTMultiple neuropathological events are involved in Alzheimer's disease (AD). The current study investigated the concurrence of neurodegeneration, increased iron content, atrophy, and demyelination in AD. Quantitative multiparameter magnetic resonance imaging (MRI) maps providing neuroimaging biomarkers for myelination and iron content along with synaptic density measurements using [18F] UCB-H PET were acquired in 24 AD and 19 Healthy controls (19 males). The whole brain voxel-wise group comparison revealed demyeli...
Source: Neurobiology of Aging - September 17, 2023 Category: Geriatrics Authors: Soodeh Moallemian Eric Salmon Mohamed Ali Bahri Nikita Beliy Emma Delhaye Evelyne Balteau Christian Degueldre Christophe Phillips Christine Bastin Source Type: research
Patterned edge-illuminated display for clinical examination of visual evoked potentials using simultaneous magnetic resonance imaging
CONCLUSIONS: The presented PEID device meets all the required standards and can be easily installed in various types of commercial magnetic resonance imaging scanners.PMID:37716181 | DOI:10.1016/j.advms.2023.09.005
Source: Advances in Medical Sciences - September 16, 2023 Category: Biomedical Science Authors: Łukasz Lisowski Łukasz Łabieniec Jolanta Lisowska Wojciech Obr ębski Joanna Konopi ńska Krzysztof Szyma ński Source Type: research
Dynamics of γ-aminobutyric acid concentration in the human brain in response to short visual stimulation
CONCLUSION: The quick response of the observed GABA concentration to the short stimulus is most likely due to a release of GABA from vesicles followed by its packaging back into vesicles.PMID:37715877 | DOI:10.1007/s10334-023-01118-7
Source: Magma - September 16, 2023 Category: Radiology Authors: Alexey Yakovlev Alexandra Gritskova Andrei Manzhurtsev Maxim Ublinskiy Petr Menshchikov Anatoly Vanin Dmitriy Kupriyanov Tolib Akhadov Natalia Semenova Source Type: research
Simultaneous quantification of Gadoxetic acid and Cisplatin in hepatocellular carcinomas using laser ablation-inductively coupled plasma-mass spectrometry
Metallomics. 2023 Sep 15:mfad052. doi: 10.1093/mtomcs/mfad052. Online ahead of print.ABSTRACTThe gadolinium-based contrast agent Gadoxetic acid and the platinum-based anti-tumor agent Cisplatin were quantitatively imaged in liver and liver cancer (hepatocellular carcinoma, HCC) tissue of rats by means of laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). HCC bearing rats simultaneously received a tail vein injection of the hepatocyte-specific magnetic resonance imaging contrast agent Gadoxetic acid and a transarterial injection of Cisplatin 15 min before sacrifice and liver removal. Resecting HCC with...
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Katharina Kronenberg Julia Werner Peter Bohrer Katja Steiger Rebecca Buchholz Maximilian von Bremen-K ühne Matthias Elinkmann Philipp M Paprottka Rickmer F Braren Fabian K Loh öfer Uwe Karst Source Type: research
